Crete

Hazard statements (CLP)

H303, H314, H331, H335

Code

Statements

H303

May be harmful if swallowed

SECTION 2: Hazards identification

Classification of the substance or mixture

Health hazards

Acute Toxicity (Oral), Category 4 Acute Toxicity (Inhalation), Category 3 Skin Irritation, Category 1B Serious Eye Damage, Category 1

2.2 Label elements

Corrosion

Environmental hazards

Skull and crossbones

Signal word

DANGER

Hazard statements

H314: Causes severe skin burns and eye damage. H303: May be harmful if swallowed. H331: Toxic if inhaled. H335: May cause respiratory irritation.

Prevention

P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P280: Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338 IF IN EYES Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P262: Do not get in eyes, on skin, or on clothing. P301+P310 IF SWALLOWED Immediately call a POISON CENTER/doctor/ P302+P352 IF ON SKIN Wash with plenty of water/ P304+P312 IF INHALED Call a POISON CENTER/doctor/...if you feel unwell P330: Rinse mouth. P331: Do NOT induce vomiting. P361: Take off immediately all contaminated clothing. P363: Wash contaminated clothing before reuse.

Potential health effects

Eye: Vapor or solution rapidly causes severe irritation of the eyes and eye lids. If not removed by thorough irrigation with water, there may be prolonged or permanent visual impairment or total loss of sight. Page 2 of 5 Skin: Contact causes severe burns unless immediately washed off. Repeat contact with dilute solutions may lead to dermatitis and photosensitization. Exposure to the concentrated vapor may result in burns or dermatitis. Chronic exposure to low concentrations causes erosion of the teeth, skin tenderness, and bleeding of the nose and gums. Dermal LD (50)(rabbit): >5010 mg/kg. Practically non-toxic. Ingestion: If swallowed causes severe burns of the mucous membrane of the mouth, esophagus and stomach. G.I. tract may perforate in extreme cases. Asphyxia may occur from edema or the larynx. The lips and mouth usually turn white, and later, brown. There is pain in the throat and stomach, difficulty in swalloing, intense thirst, nausea, and vomiting, followed by diarrhea, respiratory distress, kidney inflammation, and in severe cases, collapse and death. Oral LD (50)(rat): 700 mg/kg. Slightly toxic. Inhalation: Inhalation of excessive concentrations of gas mist vapor immediately produces severe irritation of the upper respiratory tract, resulting in coughing, burning of the throat, headaches, rapid heartbeat and a choking sensation. Inflammation, destruction of nasal passages and breathing difficulties can occur with higher concentrations and may be delayed in onset. 1000-2000 ppm can be fatal. LC (50)(rat) 3127 ppm/1 hour. Vapor has such a sharp penetrating odor that inhalation of toxic quantities is unlikely unless victim is trapped.

Principle Routes of Exposure

Inhalation, Skin Target organ statement: Eyes, Skin, Upper respiratory tract, throat, stomach Comments Chronic Toxicity exposure of 100 ppm for 6 hours a day for 50 days caused only slight unrest and irritation to the eyes and nose of rabbits, guinea pigs and pigeaons. The hemoglobin contact of the blood was also slightly diminished. Monkeys receiving twenty exposures of 33 ppm for 6 hours did not display any adverse effects. Higher exposures (unspecified) have caused weight loss which paralleled the severity of exposure. In humans, long term overexposure has been associated with erosion of the teeth.

2.1 Classification of the substance or mixture

Health hazards: Acute Toxicity (Oral), Category 4 Acute Toxicity (Inhalation), Category 3 Skin Irritation, Category 1B Serious Eye Damage, Category 1