General Information
Version
1.01
Revision date
2025-11-17
Product name
pyrimethamine
Substance name
Pyrimethamine
CAS No.
58-14-0
1.2.1 Relevant identified uses
Laboratory use
supplier name
British Pharmacopoeia Commission
Emergency telephone
+44 (0)20 3080 6561
Icons in SDS
Company Information
company name
British Pharmacopoeia Commission
e-mail address of the competent person responsible for the Safety Data Sheet
bpcrs@mhra.gov.uk
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H302, H319, H341, H360D, H362, H373, H411
Hazard statements
Code
Statements
H302
Harmful if swallowed
Section 2
SECTION 2: Hazards identification
Regulation (EC) No. 1272/2008 [CLP]] Classification of the substance or mixture Classification according to
Contains
Pyrimethamine
Signal word
Danger
Hazard statements
H302 - Harmful if swallowed. H319 - Causes serious eye irritation. H341 - Suspected of causing genetic defects. H360D - May damage the unborn child. H362 - May cause harm to breast-fed children. H373 - May cause damage to organs through prolonged or repeated exposure. H411 - Toxic to aquatic life with long lasting effects.
Precautionary statements
P201 - Obtain special instructions before use P260 - Do not breathe dust, fume, gas, mist, vapors and spray P263 - Avoid contact during pregnancy and while nursing P273 - Avoid release to the environment P280 - Wear protective gloves, protective clothing, eye protection and face protection P308 + P313 - IF exposed or concerned: Get medical advice/attention P391 - Collect spillage P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P337 + P313 - If eye irritation persists: Get medical advice/attention
2.3 Other hazards
Toxic to aquatic life.
PBT Substances
& vPvB This substance does not meet the PBT/vPvB criteria of REACH, annex XIII. Endocrine Disruptor Information This product does not contain any known or suspected endocrine disruptors. Chemical name
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No. 1272/2008 [CLP] Acute toxicity - Oral Category 4 - (H302) Eye irritation Category 2 - (H319) Germ cell mutagenicity Category 2 - (H341) Reproductive toxicity Category 1B - (H360D) Effects on or via lactation Yes - (H362) Specific target organ toxicity (repeated exposure) Category 2 - (H373) Hazardous to the aquatic environment - chronic Category 2 - (H411)