Kenalog Ointments (0.025%, 0.1%, 0.5%)

SECTION 2: Hazards identification

Emergency Overview: Kenalog Ointments contain the potent glucocorticoid, triamcinolone acetonide. This drug may be absorbed through the skin. See Health Effects section for additional information. Applies to All Ingredients

Principle Routes of Exposure

Inhalation: Exposure to this material by inhalation is not expected to occur. Skin Contact: Exposure may occur via skin contact if gloves and protective clothing are not worn. Triamcinolone acetonide, which is a glucocorticoid, may be well absorbed after skin contact. Ingestion: Ingestion of large quantities of this material in an occupational setting would not be expected to occur. Ingestion of trace amounts of the material might occur if material contacts hands and hands are not washed prior to eating, drinking, or smoking. Triamcinolone acetonide may be absorbed after ingestion.

Potential health effects

Eye Contact: Acute: Material contains heavy mineral oil, which is a mild eye irritant. Signs associated with eye irritation may include redness, tearing, swelling, pain. Skin Contact: Acute: Toxic: Material contains a highly potent drug which is known to be absorbed through the skin. If there is sufficient and repeated skin contact with this material, some of the systemic effects described under acute ingestion and under chronic effects may be possible, particularly if material contacts large areas of the body, when the exposure period is prolonged and when contact area is covered by an occlusive dressing or material. Irritation: Dermatological effects, including burning, itching, irritation, drying, cracking, or tightening of the skin; thinning of the skin; acneiformeruption; erythema; folliculitis; hypertrichosis; allergic contact dermatitis and other 2 skin disorders are reported infrequently when topical corticosteroids are used therapeutically. These reactions may occur more frequently if contact area is covered by an occlusive material. Inhalation: Acute: Inhalation is not expected to occur due to physical form of the product. Ingestion: Acute: The active drug, triamcinolone acetonide has low toxicity after acute ingestion. Inadvertent ingestion of trace amounts of this ointment would not be expected to result in harmful effects. Repeated ingestion of high doses might result in symptoms such as headache, dizziness, fatigue, faintness and endocrine symptoms.

Potential chronic health

Exposure (by ingestion or skin contact) to high doses for prolonged periods might result in effects such as: muscle weakness and fatigue, changes in the matrix of the bones, headache, vertigo, other nervous system effects, skin changes, hyperglycemia, peptic ulcer, cataract development, menstrual difficulties, fluid and electrolyte disturbances and adrenal suppression. Carcinogenicity

TOXICOLOGICAL INFORMATION

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