General Information
Version
1.0, 29.10.2021
Revision date
2021-10-29
Product name
Fedratinib hydrochloride (USAN)
Product Synonyms
BMS-847943-02; Inrebic; N-tert-butyl-3-[(5-methyl-2-{[4-(2-pyrrolidin-1- BMS-847943-02; Inrebic; N-tert-butyl-3-[(5-methyl-2-{[4-(2-pyrrolidin-1- ylethoxy)phenyl]amino}pyrimidin-4-yl)amino]benzenesulfonamide dihydrochloride monohydrate; SAR302503A (dihydrochloride monohydrate salt) - formerly TG101348; SAR302503 (free base) C17051538-B; TG101568
Chemical name
Benzenesulfonamide, N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1- pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]-, hydrochloride, hydrate (1 2 1)
CAS No.
1374744-69-0
1.2.1 Relevant identified uses
This material is the active pharmaceutical ingredient (API) in a drug product. It is used in the treatment of cancer
Emergency telephone
353-1813-9456
Icons in SDS
Company Information
company name
Bristol-Myers Squibb Company
e-mail address of the competent person responsible for the Safety Data Sheet
MG-GBS-MSDS-Request@bms.com
GHS Information
Signal word
Danger
Section 2
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Toxic To Reproduction - Developmental Toxicity - Category 2 Specific Target Organ Systemic Toxicity (Repeated Exposure) - Category 1 Hazardous To The Aquatic Environment - Acute Hazard - Category 1 Hazardous To The Aquatic Environment - Chronic Hazard - Category 1
Signal word
Danger
Hazard statements
Suspected of damaging the unborn child (developmental toxicity) . Causes damage to organs (hematopoietic system, gastrointestinal tract, liver, kidney, central nervous system, cardiovascular system) through prolonged or repeated exposure. Very toxic to aquatic life. Very toxic to aquatic life with long lasting effects.
Precautionary statements
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Use personal protective equipment as required. Do not breathe dust. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Avoid release to the environment. Collect spillage.
