Transglutaminase Activity Assay Kit (Colorimetric)

Hazard statements (CLP)

H290, H302, H302+H312, H303, H312, H314, H315, H317, H318, H319, H335, H351, H373, H400, H402, H410

Code

Statements

H290

May be corrosive to metals

SECTION 2: Hazards identification

OSHA Hazards Component Description Volume Safety Information TG Assay Buffer Proprietary buffer 12 ml No hazards Homogenization Buffer (10x) Proprietary buffer (EDTA) 10 ml See Below 1M DTT

Contains

DTT 125 µl See Below Donor Substrate Lyophilized 1 vial No hazards Acceptor Substrate Hydroxylamine HCl 2 vials See Below Hydroxamate Standard Lyophilized 1 vial No hazards Stop Solution Liquid (contains TCA & Iron chloride) 5 ml See below Positive Control Lyophilized 1 vial No hazards Plate Sealer -- 1 No hazards EDTA: Emergency Overview

2.1 Classification of the substance or mixture

Eye irritation (Category 2A), H319 Short-term (acute) aquatic hazard (Category 3), H402 Acute toxicity, Oral (Category 5) Skin irritation (Category 2) Eye irritation (Category 2A) Corrosive to metals (Category 1), H290 Acute toxicity, Oral (Category 4), H302 Acute toxicity, Dermal (Category 4), H312 Skin irritation (Category 2), H315 Eye irritation (Category 2A), H319 Skin sensitisation (Category 1), H317 Carcinogenicity (Category 2), H351 Specific target organ toxicity - repeated exposure, Oral (Category 2), spleen, H373 Short-term (acute) aquatic hazard (Category 1), H400

Signal word

Warning Warning Warning Danger Danger

Hazard statements

H319: Causes serious eye irritation. H402 Harmful to aquatic life. H303 May be harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H290 May be corrosive to metals. H302 + H312 Harmful if swallowed or in contact with skin. H315 Causes skin irritation. H317 May cause an allergic skin reaction. H319 Causes serious eye irritation. H351 Suspected of causing cancer. H373 May cause damage to organs (spleen) through prolonged or repeated exposure if swallowed. H400 Very toxic to aquatic life. H314 Causes severe skin burns and eye damage. H335 May cause respiratory irritation. H410 Very toxic to aquatic life with long lasting effects. H290 May be corrosive to metals. H302 Harmful if swallowed. H315 Causes skin irritation. H318 Causes serious eye damage.

Precautionary statements

P264 Wash skin thoroughly after handling P273 Avoid release to the environment. P280 Wear eye protection/ face protection. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 If eye irritation persists: Get medical advice/ attention. P501 Dispose of contents/ container to an approved waste disposal plant. P305+P351+P338 IF IN EYES Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P201 Obtain special instructions before use P202 Do not handle until all safety precautions have been read and understood. P234 Keep only in original container. P260 Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P272 Contaminated work clothing must not be allowed out of the workplace. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P312 + P330 IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P302 + P352 + P312 IF ON SKIN: Wash with plenty of water. Call a POISON CENTER/doctor if you feel unwell. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P333 + P313 If skin irritation or rash occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. P390 Absorb spillage to prevent material damage. P391 Collect spillage. P405 Store locked up. P406 Store in corrosive resistant container with a resistant inner liner. P501 Dispose of contents/ container to an approved waste disposal plant. P260 Do not breathe dust or mist P264 Wash skin thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P330 + P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 + P310 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. P363 Wash contaminated clothing before reuse. P391 Collect spillage. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plan P234 Keep only in original container P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/ eye protection/ face protection. P301 + P312 + P330 IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. Rinse mouth. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P305 + P351 + P338 + P310 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/ doctor. P332 + P313 If skin irritation occurs: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. P390 Absorb spillage to prevent material damage. P406 Store in corrosive resistant container with a resistant inner liner. P501 Dispose of contents/ container to an approved waste disposal plant

Health hazards

1 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0 2 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0 3 Flammability: 0 3 Fire: 0 Reactivity Hazard: 0 2 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0 Iron(III) chloride: Emergency overview 2 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0

Physical hazards

0 0 0 0 0

Potential health effects

Inhalation: May be harmful if inhaled. Causes respiratory tract irritation. Skin: May be harmful if absorbed through skin. Causes skin irritation. Eyes: Causes eye irritation. Ingestion: Toxic if swallowed. DTT: Emergency Overview Inhalation: May be harmful if inhaled. Causes respiratory tract irritation. Skin: May be harmful if absorbed through skin. Causes skin irritation. Eyes: Causes eye irritation. Ingestion: Toxic if swallowed. Hydroxylamine HCl: Emergency Overview Inhalation: May be harmful if inhaled. Causes respiratory tract irritation. Skin: May be harmful if absorbed through skin. Causes skin irritation. Eyes: Causes eye irritation. Ingestion: Toxic if swallowed Trichloroacetic acid (TCA): Emergency overview

2.3 Other hazards

Target Organ Effect, Toxic by ingestion, Irritant Target Organs: Central nervous system Target Organ Effect, Toxic by ingestion, Irritant Target Organs: Central nervous system

OSHA HCS Classification

Skin corrosion (Category 1A), H314 Serious eye damage (Category 1), H318 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335 Short-term (acute) aquatic hazard (Category 1), H400 Long-term (chronic) aquatic hazard (Category 1), H410 Corrosive to Metals (Category 1), H290 Acute toxicity, Oral (Category 4), H302 Skin irritation (Category 2), H315 Serious eye damage (Category 1), H318