Sirtuin Activity Assay Kit (Fluorometric)

Hazard statements (CLP)

H227, H302, H315, H317, H319, H334, H335

Code

Statements

H227

Combustible liquid

SECTION 2: Hazards identification

OSHA Hazards Component Description Volume Safety Information Assay Buffer Proprietary Buffer 25 ml No hazards Homogenization Buffer Liquid 100 ml No hazards 1M DTT Liquid 0.4 ml See below Substrate In DMSO 0.2 ml See below NAD Liquid 1 vial No hazards Positive Control Liquid 20 µl No hazards Trichostatin A (in DMSO)

Contains

Trichostatin A in DMSO 50 µl See below Developer Trypsin 1 ml See below AFC Standard (in DMSO) (1 mM) in DMSO 0.1 ml See below DTT: Emergency Overview

2.1 Classification of the substance or mixture

Acute toxicity, Oral (Category 4) Skin irritation (Category 2) Eye irritation (Category 2A) Specific target organ toxicity - single exposure Flammable liquids (Category 4) Skin irritation (Category 2) Eye irritation (Category 2A) Respiratory sensitization (Category 1) Skin sensitization (Category 1) Specific target organ toxicity – single exposure (Category 3)

Signal word

Warning Warning Danger

Hazard statements

H302 Harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation. H227 Combustible liquid H315 Causes skin irritation. H317 May cause an allergic skin reaction. H319 Causes serious eye irritation. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H335 May cause respiratory irritation.

Precautionary statements

P264 Wash skin thoroughly after handling P280 Wear eye protection/ face protection. P280 Wear protective gloves. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P332 + P313 If skin irritation occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. none P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray P264 Wash skin thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/ eye protection/ face protection. P285 In case of inadequate ventilation wear respiratory protection. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P321 Specific treatment (see supplemental first aid instructions on this label). P333 + P313 If skin irritation or rash occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P342 + P311 If experiencing respiratory symptoms: Call a POISON CENTER or doctor/ physician. P362 Take off contaminated clothing and wash before reuse. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant.

Health hazards

2 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0 0 Flammability: 2 0 Fire: 2 Reactivity Hazard: 0 2 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0

Physical hazards

0 0 0

Potential health effects

Inhalation: May be harmful if inhaled. Causes respiratory tract irritation. Skin: May be harmful if absorbed through skin. Causes skin irritation. Eyes: Causes eye irritation. Ingestion: Harmful if swallowed. DMSO: Emergency Overview Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed.

2.3 Other hazards

Combustible liquid, Target organ effect Target Organs: Eyes, Skin Target organ effect, Skin and respiratory sensitizer, Irritant Target Organs: Lungs

Hazard pictograms

none

Medical Conditions Generally Aggravated by Exposure

Avoid contact w/DMSO solutions containing toxic materials or materials with unknown toxicological properties. DMSO is readily absorbed through skin and may carry such materials into the body. Trypsin: Emergency Overview