Phospho-ERK MAPK (Thr202 Tyr204) Translocation Assay Kit

Hazard statements (CLP)

H227, H302, H312, H317, H318, H334, H350, H351, H360, H402

Code

Statements

H227

Combustible liquid

SECTION 2: Hazards identification

NFPA Rating Component Description Volume Safety Information Fixative Solution Solution (Contains formaldehyde) 10 ml See below Blocking Buffer Liquid 10 ml No hazards Wash Buffer Liquid 75 ml No hazards Phospho-ERK1/2 Primary Liquid 50 µl No hazards Antibody (100X) Secondary Antibody (100X) Liquid 50 µl No hazards Tamoxifen (1000X) Tamoxifen in DMSO 30 µl See below DAPI (1000X) Liquid 20 µl No hazards Formaldehyde: Emergency Overview

2.3 Other hazards

Target organ effect, Toxic by ingestion, Toxic by skin absorption, Skin and respiratory sensitizer, Corrosive, Carcinogen Target Organs: Eyes, Kidney, Liver, Heart Target organ effect, Harmful by ingestion, Carcinogen, Teratogen, Reproductive hazard Target Organs: Male reproductive system, Female reproductive system, Eyes, Liver Combustible liquid, Target organ effect Target Organs: Eyes, Skin

2.1 Classification of the substance or mixture

Acute toxicity, Oral (Category 3) Acute toxicity, Dermal (Category 3) Serious eye damage (Category 1) Skin irritation (Category 2) Respiratory sensitization (Category 1) Skin sensitization (Category 1) Carcinogenicity (Category 2) Acute aquatic toxicity (Category 3) Acute toxicity, Oral (Category 4) Carcinogenicity (Category 1B) Reproductive toxicity (Category 1B) Flammable liquids (Category 4)

Signal word

warning Danger Warning

Hazard statements

H302: Harmful if swallowed. H312: Harmful in contact with skin H317 May cause an allergic skin reaction. H318 Causes serious eye damage. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H351 Suspected of causing cancer. H402 Harmful to aquatic life. H302 Harmful if swallowed. H350 May cause cancer. H360 May damage fertility or the unborn child. H227 Combustible liquid

Precautionary statements

P261 Avoid breathing dust/fumes/gas/mist/vapors/spray P264 Wash hands thoroughly after handling. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P311 Call a POISON CENTER or doctor/physician. P201 Obtain special instructions before use P308+P313 IF exposed or concerned: Get medical advice/attention. none

Health hazards

3 Flammability: 0 3 Fire: 0 Reactivity Hazard: 0 1 Flammability: 0 1 Fire: 0 Reactivity Hazard: 0 0 Flammability: 2 0 Fire: 2 Reactivity Hazard: 0

Physical hazards

0 0 0

Potential health effects

Inhalation: May be harmful if inhaled. Material is extremely destructive to the tissue of the mucous membranes and upper respiratory tract. Skin: Toxic if absorbed through skin. Causes skin burns. Eyes: Causes eye burns. Ingestion: Toxic if swallowed. Tamoxifen citrate: Emergency Overview Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: Harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: Harmful if swallowed. DMSO: Emergency Overview Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed.

Hazard pictograms

none

Medical Conditions Generally Aggravated by Exposure

Avoid contact w/DMSO solutions containing toxic materials or materials with unknown toxicological properties. DMSO is readily absorbed through skin and may carry such materials into the body.