p53 Nuclear Translocation Assay Kit (Cell-Based)

Hazard statements (CLP)

H227, H302, H312, H313, H315, H317, H318, H334, H351, H400, H402

Code

Statements

H227

Combustible liquid

SECTION 2: Hazards identification

NFPA Rating Component Description Volume Safety Information 1X Fixative Solution Solution (Contains formaldehyde and glutaraldehyde) 15 ml See below 1X Permeabilization Buffer Liquid 15 ml No hazards 1X Blocking Buffer 40 ml Liquid No hazards p53 Primary Antibody (500X) 30 µl Liquid No hazards p53 Secondary Antibody 30 µl Liquid (500X) No hazards Nutlin-3 Reagent (200X) 30 µl

Contains

DMSO See below DAPI (1000X) Liquid 20 μl No hazards Formaldehyde: Emergency Overview

2.3 Other hazards

Target organ effect, Toxic by ingestion, Toxic by skin absorption, Skin and respiratory sensitizer, Corrosive, Carcinogen Target Organs: Eyes, Kidney, Liver, Heart Target organ effect, Toxic by ingestion, Toxic by inhalation, Skin sensitizer, Respiratory sensitizer, Corrosive Target Organs: Central nervous system, Heart Combustible liquid, Target organ effect Target Organs: Eyes, Skin

2.1 Classification of the substance or mixture

Acute toxicity, Oral (Category 3) Acute toxicity, Dermal (Category 3) Serious eye damage (Category 1) Skin irritation (Category 2) Respiratory sensitization (Category 1) Skin sensitization (Category 1) Carcinogenicity (Category 2) Acute aquatic toxicity (Category 3) Acute toxicity, Oral (Category 3) Acute toxicity, Inhalation (Category 2) Acute toxicity, Dermal (Category 5) Serious eye damage (Category 1) Skin irritation (Category 2) Respiratory sensitization (Category 1) Skin sensitization (Category 1) Acute aquatic toxicity (Category 1) Flammable liquids (Category 4)

Signal word

warning warning Warning

Hazard statements

H302: Harmful if swallowed. H312: Harmful in contact with skin H317 May cause an allergic skin reaction. H318 Causes serious eye damage. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H351 Suspected of causing cancer. H402 Harmful to aquatic life. H302 Harmful if swallowed. H313 May be harmful in contact with skin. H315 Causes skin irritation. H317 May cause an allergic skin reaction. H318 Causes serious eye damage. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H400 very toxic to aquatic life. H227 Combustible liquid

Precautionary statements

P261 Avoid breathing dust/fumes/gas/mist/vapors/spray. P264 Wash hands thoroughly after handling. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P311 Call a POISON CENTER or doctor/physician. P260 Do not breathe dust/fumes/gas/mist/vapors/spray. P264 Wash hands thoroughly after handling. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310 Immediately call a POISON CENTER or doctor/physician. none

Health hazards

3 Flammability: 0 3 Fire: 0 Reactivity Hazard: 0 3 Flammability: 0 4 Fire: 0 Reactivity Hazard: 0 0 Flammability: 2 0 Fire: 2 Reactivity Hazard: 0

Physical hazards

0 1 0

Potential health effects

Inhalation: May be harmful if inhaled. Material is extremely destructive to the tissue of the mucous membranes and upper respiratory tract. Skin: Toxic if absorbed through skin. Causes skin burns. Eyes: Causes eye burns. Ingestion: Toxic if swallowed. Glutaraldehyde: Emergency Overview Inhalation: Toxic if inhaled. Material is extremely destructive to the tissue of the mucous membranes and upper respiratory tract. Skin: May be harmful if absorbed through skin. Causes skin burns. Eyes: Causes eye burns. Ingestion: Toxic if swallowed. DMSO: Emergency Overview Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed.

Hazard pictograms

none

Medical Conditions Generally Aggravated by Exposure

Avoid contact w/DMSO solutions containing toxic materials or materials with unknown toxicological properties. DMSO is readily absorbed through skin and may carry such materials into the body.