Nitric Oxide Synthase Activity Assay Kit II (Colorimetric)

Hazard statements (CLP)

H272, H290, H301, H302, H313, H315, H317, H319, H335, H350, H400, H410

Code

Statements

H272

May intensify fire; oxidiser

SECTION 2: Hazards identification

OSHA Hazards Component Description Amount Safety Information NOS Assay Buffer Liquid (contains Tergitol) 25 ml See below NOS Lysis Buffer Liquid (contains Glycerol) 25 ml See below NOS Substrate Liquid 0.5 ml No hazards NOS Cofactor 1 Lyophilized 1 vial No hazards NOS Cofactor 2 (25X) Liquid 0.1 ml No hazards Nitrate Reductase Lyophilized 1 vial No hazards NOS (Positive Control) Liquid 50 µl No hazards Enhancer Lyophilized 1 vial No hazards Nitrite Standard

Contains

Sodium nitrite 1 vial See below Griess Reagent 1 Solution (contains phosphoric acid) 10 ml See below Griess Reagent 2 Solution (contains NED) 10 ml See below Tergitol: Emergency Overview

2.1 Classification of the substance or mixture

Skin irritation (Category 2), H315 Skin sensitization (Sub-category 1A), H317 Short-term (acute) aquatic hazard (Category 1), H400 Long-term (chronic) aquatic hazard (Category 1), H410 Skin irritation (Category 3) Eye irritation (Category 2B) Oxidizing solids (Category 3) Acute toxicity, Oral (Category 3) Eye irritation (Category 2A) Acute aquatic toxicity (Category 1) Acute toxicity, Oral (Category 4) Acute toxicity, Inhalation (Category 2) Acute toxicity, Dermal (Category 5) Skin corrosion (Category 1B) Serious eye damage (Category 1) Corrosive to Metals (Category 1), H290 Skin irritation (Category 2) Eye irritation (Category 2A) Specific target organ toxicity – single exposure (Category 3)

Signal word

Warning none Danger Warning Warning

Hazard statements

H315 Causes skin irritation. H317 May cause an allergic skin reaction. H410 Very toxic to aquatic life with long lasting effects. none H272 May intensify fire; oxidizer. H301 Toxic if swallowed. H319 Causes serious eye irritation. H350: May cause cancer H400 Very toxic to aquatic life.. H302 Harmful if swallowed. H313 May be harmful in contact with skin. H315: Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation.

Precautionary statements

P261 Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray P264 Wash skin thoroughly after handling. P272 Contaminated work clothing must not be allowed out of the workplace. P273 Avoid release to the environment. P280 Wear protective gloves. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P333 + P313 If skin irritation or rash occurs: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. P391 Collect spillage. P501 Dispose of contents/ container to an approved waste disposalplant P305+P351+P338 IF IN EYES Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P220 Keep/store away from clothing/combustible materials P273 Avoid release to the environment. P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P260 Do not breathe dust/fumes/gas/mist/vapors/spray P280 Wear protective gloves/eye protection/face protection. P284 Wear respiratory protection. P301+P312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P303+P361+P353 IF ON SKIN (or hair): Remove/take off immediately all contaminated clothing. Rinse skin with water/shower. P304+P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310 Immediately call a POISON CENTER or doctor/ physician. P261 Avoid breathing dust/fume/gas/mist/vapors/spray P264 Wash skin thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/eye protection/face protection. P302+P352 IF ON SKIN: Wash with plenty of soap and water. P304+P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312 Call a POISON CENTER or doctor/physician if you feel unwell. P332+P313 If skin irritatation occurs: Get medical advice/attention. P337+P313 If eye irritation persists: Get medical advice/attention.

Health hazards

Flammability: 0 Flammability: 1 Flammability: 0 Flammability: 0

Physical hazards

0 0 1 0

NFPA Ratings

Fire: 0 Reactivity hazard: 0 Fire: 1 Reactivity Hazard: 0 Fire: 0 Reactivity Hazard: 1 Special Hazard: OX Fire: 0 Reactivity hazard: 0

Potential health effects

Inhalation: May be harmful if inhaled. Material is irritating to the tissue of the mucous membranes and upper respiratory tract.Harmful; if inhaled. May cause allergy or asthma symptoms or breathing difficulties. Skin: May be harmful if absorbed through skin. May cause an allergic skin reaction. Eyes: Causes eye irritation. Ingestion: Harmful if swallowed. To the best of our knowledge, the toxicological properties have not been thoroughly investigated Glycerol: Emergency Overview Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed. Sodium nitrite: Emergency Overview Inhalation: May be harmful if inhaled. Causes respiratory tract irritation. Skin: May be harmful if absorbed through skin. Causes skin irritation. Eyes: Causes eye irritation. Ingestion: Toxic if swallowed. Phosphoric acid: Emergency Overview Inhalation: May be fatal if inhaled. Material is extremely destructive to the tissue of the mucous membranes and upper respiratory tract. Skin: Harmful if absorbed through skin. Causes skin burns. Eyes: Causes eye burns. Ingestion: Harmful if swallowed. NED: Emergency Overview Inhalation: May be harmful if inhaled. Causes respiratory tract irritation. Skin: May be harmful if absorbed through skin. Causes skin irritation. Eyes: Causes eye irritation. Ingestion: May be harmful if swallowed.

2.3 Other hazards

Target Organ Effect Target Organs: Kidney Oxidizer, Carcinogen, Target organ effect, Toxic by ingestion, Irritant Target Organs: Blood, Cardiovascular system, Smooth muscle Target organ effect, Highly toxic by inhalation, Harmful by ingestion, Corrosive Target Organs: Liver, Blood, Bone marrow Irritant

Hazard pictograms

none

HMIS® ratings

Fire: 0 Reactivity Hazard: 1