Nitric Oxide Fluorometric Assay Kit

Hazard statements (CLP)

H272, H290, H301, H314, H318, H319, H400, H402

Code

Statements

H272

May intensify fire; oxidiser

SECTION 2: Hazards identification

No 1272/2008 Component Description Volume Safety Information Assay Buffer Proprietary Buffer 50 ml No hazards Enzyme Cofactor Lyophilized -- No hazards Enhancer Lyophilized (contains Methoxy PMS) -- See below Nitrate Reductase Lyophilized -- No hazards Nitrate Standard Lyophilized (contains sodium nitrate) -- See below Nitrite Standard Lyophilized (contains sodium nitrite) -- See below DAN Probe Liquid (contains HCl) 1 ml See below Sodium Hydroxide Liquid 1 ml See below 96-Well White Plate -- 2 No hazards Plate Cover -- 2 No hazards NOTE The safety data shown below is based on pure ingredients The amount in this kit comprises much less Methoxy-PMS: Emergency Overview

2.1 Classification of the substance or mixture

Health hazard: 2 Flammability: 0 Physical hazards: 0 NFPA Rating Health Hazard: 2 Fire: 0 Reactivity Hazard: 0 Potential health hazard Causes serious eye irritation. Causes skin irritation. Harmful if swallowed. Material may be irritating to the mucous membranes and upper respiratory tract. May be harmful by inhalation or skin absorption. May cause respiratory system irritation. Suspected of causing cancer Sodium nitrate: Emergency Overview GHS Classification: Oxidizing solids (Category 3), H272

2.2 Label elements

including precautionary statementsPictogram

Signal word

Warning Warning Hazard statement(s) H272 May intensify fire; oxidizer H319 Causes serious eye irritation Precautionary statement(s): P210 Keep away from heat P220 Keep/Store away from clothing/ combustible materials P221 Take any precaution to avoid mixing with combustibles P264 Wash skin thoroughly after handling P280 Wear protective gloves/ eye protection/ face protection P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P337 + P313 If eye irritation persists: Get medical advice/ attention P370 + P378 In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish P501 Dispose of contents/ container to an approved waste disposal plant Danger Danger Danger

Hazard statements

H302 Harmful if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H351 Suspected of causing cancer. H272 May intensify fire; oxidizer. H301 Toxic if swallowed. H319 Causes serious eye irritation. H400 Very toxic to aquatic life. H290 May be corrosive to metals. H314 Causes severe skin burns and eye damage. H402 Harmful to aquatic life. H290 May be corrosive to metals. H314 Causes severe skin burns and eye damage. H318 Causes serious eye damage. H402 Harmful to aquatic life.

Precautionary statements

P201 Obtain special instructions before use P202 Do not handle until all safety precautions have been read and understood. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/ eye protection/ face protection. P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P321 Specific treatment (see supplemental first aid instructions on this label). P330 Rinse mouth. P332 + P313 If skin irritation occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant. P210 Keep away from heat P220 Keep/Store away from clothing/ combustible materials. P221 Take any precaution to avoid mixing with combustibles. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment. P280 Wear protective gloves/ eye protection/ face protection. P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER/doctor.Rinse mouth. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes.Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 If eye irritation persists: Get medical advice/ attention. P370 + P378 In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish. P391 Collect spillage. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant P234 Keep only in original container P260 Do not breathe dust or mist. P264 Wash skin thoroughly after handling. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P330 + P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 If eye irritation persists: Get medical advice/ attention. P363 Wash contaminated clothing before reuse. P390 Absorb spillage to prevent material damage. P405 Store locked up. P406 Store in corrosive resistant container with a resistant inner liner. P501 Dispose of contents/ container to an approved waste disposal plant. P234 Keep only in original container P264 Wash skin thoroughly after handling. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P330 + P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER or doctor/ physician. P305 + P351 + P338 + P310 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/ physician. P363 Wash contaminated clothing before reuse. P390 Absorb spillage to prevent material damage. P405 Store locked up. P406 Store in corrosive resistant stainless steel container with a resistant inner liner. P501 Dispose of contents/ container to an approved waste disposal plant.

Health hazards

2 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0 Causes serious eye irritation Causes skin irritation Harmful if swallowed Material may be irritating to the mucous membranes and upper respiratory tract May be harmful by inhalation or skin absorption May cause respiratory system irritation Suspected of causing cancer Sodium nitrate Emergency Overview GHS Classification: Oxidizing solids (Category 3), H272 Eye irritation (Category 2A), H319 GHS Label elements, including precautionary statements Pictogram Flammability Fire Reactivity Hazard Sodium nitrite Emergency Overview GHS Classification:Oxidizing solids (Category 3), H272 Acute toxicity, Oral (Category 3), H301 Eye irritation (Category 2A), H319 Short-term (acute) aquatic hazard (Category 1), H400 0 Flammability: 3 0 Fire: 3 Reactivity Hazard: 0 2 Flammability: 1 1 Fire: 1 Reactivity Hazard: 0 3 Flammability: 0 3 Fire: 0 Reactivity Hazard: 0

Physical hazards

0 NFPA Rating NFPA Rating 0 0 1

Potential health effects

Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: Toxic if swallowed. Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed Sodium hydroxide (NaOH): Inhalation: May be harmful if inhaled. Material is extremely destructive to the tissue of the mucous membranes and upper respiratory tract. Skin: May be harmful if absorbed through skin. Causes skin burns. Eyes: Causes severe eye burns. Ingestion: May be harmful if swallowed

Medical Conditions Generally Aggravated by Exposure

Avoid contact w/DMSO solutions containing toxic materials or materials with unknown toxicological properties. DMSO is readily absorbed through skin and may carry such materials into the body. HCl: Emergency Overview