N′-Nicotinamide Methyltransferase (NNMT) Inhibitor Screening Assay

BioVision, Inc

Revision date : 2015-03-11

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GHS02 GHS07
Health risk rating 2
Safety risk rating 2
Environmental risk rating 1

Note: Ingredients listed on restricted chemical lists

EC/CAS

67-68-5

Name of the chemical

dimethyl sulphoxide

Concentration

N/A

EC/CAS

64-17-5

Name of the chemical

Ethanol

Concentration

N/A

EC/CAS

200-664-3

Name of the chemical

Dimethyl sulfoxide (INN)

Concentration

N/A

General Information

Revision date

2015-03-11

Product name

N′-Nicotinamide Methyltransferase (NNMT) Inhibitor Screening Assay

Manufacturer Name

BioVision, Inc

Emergency telephone

OTHER CALLS

Icons in SDS

GHS02

Company Information

company name

BioVision, Inc

GHS Information

Signal word

Warning

Hazard Codes

Hazard statements (CLP)

H226, H227

Hazard statements

Code

Statements

H226

Flammable liquid and vapour

Section 2

SECTION 2: Hazards identification

NFPA Rating Component Description Volume Safety Information NNMT Assay Buffer Proprietary Buffer 22 ml No hazards NNMT Enzyme Proprietary Buffer 50 µl No hazards S-Adenosylmethionine (SAM) Lyophilized SAM 4 x No hazards Lyophilized Nicotinamide Liquid 4 ml No hazards Enzyme-I In Proprietary Buffer 200 µl No hazards Enzyme-II Lyophilized No hazards 1-Methylnicotinamide (MNA) Liquid 20 µl No hazards Thiol Detecting Probe In DMSO 200 µl See below SAM Reconstitution Buffer Proprietary Buffer (contains 10% Ethanol) 500 µl See below DMSO: Emergency Overview

2.3 Other hazards

Combustible liquid, Target organ effect Target Organs: Eyes, Skin

2.1 Classification of the substance or mixture

Flammable liquids (Category 4) Flammable liquids (Category 3) Skin irritation (Category 2) Eye irritation (Category 2B) Specific target organ toxicity – single exposure (Category 3)

Hazard pictograms

none

Signal word

Warning Warning

Hazard statements

H227 Combustible liquid H226 Flammable liquid and vapor.

Precautionary statements

none P210 Keep away from heat/sparks/open flames/hot surfaces. No smoking P261 Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Health hazards

0 Flammability: 2 0 Fire: 2 Reactivity Hazard: 0 2 Flammability: 2 2 Fire: 2 Reactivity Hazard: 0

Physical hazards

0 0

Potential health effects

Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed. Inhalation: May be harmful if inhaled. Causes respiratory tract irritation. Skin: May be harmful if absorbed through skin. Causes skin irritation. Eyes: Causes eye irritation. Ingestion: May be harmful if swallowed.

Medical Conditions Generally Aggravated by Exposure

Avoid contact w/DMSO solutions containing toxic materials or materials with unknown toxicological properties. DMSO is readily absorbed through skin and may carry such materials into the body. 10% Ethanol: Emergency Overview

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