Human Calpain 1 Inhibitor Screening Kit

Hazard statements (CLP)

H227

Code

Statements

H227

Combustible liquid

SECTION 2: Hazards identification

NFPA Rating Component Description Volume Safety Information Assay Buffer Proprietary Buffer (contains CHAPS) 25 ml See below Substrate In DMSO 0.2 ml See below Calpain 1 Enzyme Solution (contains glycerol) 0.2 ml See below Inhibitor Control 1 µM solution (contains CHAPS) 0.5 ml See below (Calpain Inhibitor 1, ALLN) CHAPS: Emergency Overview

2.3 Other hazards

Irritant Combustible liquid, Target organ effect Target Organs: Eyes, Skin Target Organ Effect Target Organs: Kidney

2.1 Classification of the substance or mixture

Acute toxicity, Oral (Category 4) Skin irritation (Category 2) Eye irritation (Category 2A) Flammable liquids (Category 4) Skin irritation (Category 3) Eye irritation (Category 2B)

Hazard pictograms

none none none

Signal word

none Warning none

Hazard statements

none. H227 Combustible liquid none

Precautionary statements

P281 Use personal protective equipment as required P301+P312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P302+P352 IF ON SKIN: Wash with plenty of soap and water. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P332+P313 If skin irritation persists: Get medical advice/attention. P337+P313 If eye irritation persists: Get medical advice/attention. none P305+P351+P338 IF IN EYES Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Health hazards

2 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0 0 Flammability: 2 0 Fire: 2 Reactivity Hazard: 0 1 Flammability: 1 1 Fire: 1 Reactivity Hazard: 0

Physical hazards

0 0 0

Potential health effects

Inhalation: May be harmful if inhaled. Causes respiratory tract irritation. Skin: May be harmful if absorbed through skin. Causes skin irritation. Eyes: Causes eye irritation. Ingestion: Harmful if swallowed. DMSO: Emergency Overview Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed. Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed.

Medical Conditions Generally Aggravated by Exposure

Avoid contact w/DMSO solutions containing toxic materials or materials with unknown toxicological properties. DMSO is readily absorbed through skin and may carry such materials into the body. Glycerol: Emergency Overview