DiscoveryPak Stem Cell Fate Regulator Set VII

Hazard statements (CLP)

H300, H301, H302, H303, H311+H331, H315, H319, H335, H341, H361d

Code

Statements

H300

Fatal if swallowed

SECTION 2: Hazards identification

NFPA Rating Component Description Volume Safety Information (±) –Bay K 8644 Solid 5 mg See Below BIX01294 Solid 5 mg No Hazard PS-48 Solid 5 mg See Below RepSox Solid 5 mg No Hazard Reversine Solid 1 mg See Below RG108 Solid 10 mg No Hazard SB-431542 Solid 1 mg No Hazard Sodium Butyrate Solid 1 g See Below Tranylcypromine Hemisulfate (Parnate) Solid 25 mg See Below Valproic Acid, sodium salt (VPA) Solid 200 mg See Below (±)-Bay K8644: Emergency Overview

2.3 Other hazards

Irritant No known OSHA hazards Toxic by ingestion Target organ effect, Irritant, Mutagen Target Organs: Blood Target organ effect, Highly toxic by inhalation, Highly toxic by ingestion, Toxic by skin absorption Target Organs: Heart, Liver Target organ effect, Harmful by ingestion Target Organs: Central nervous system, Liver

2.1 Classification of the substance or mixture

Eye irritation (Category 2A) Skin irritation (Category 2) Acute toxicity, Oral (Category 5) Acute toxicity, Oral (Category 3) Skin irritation (Category 1) Eye irritation (Category 2A) Germ cell mutagenicity (Category 2) Specific target organ toxicity – single exposure (Category 3) Acute toxicity, Oral (Category 2) Acute toxicity, Inhalation (Category 2) Acute toxicity, Dermal (Category 3) Specific target organ toxicity, repeated exposure (Category 2) Acute toxicity, Oral (Category 4)

Signal word

Warning Warning Danger Warning Danger Warning

Hazard statements

H315 Causes skin irritation. H319 Causes serious eye irritation. H303 May be harmful if swallowed. H301 Toxic if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. H341 Suspected of causing genetic defects. H300 Fatal if swallowed. H311 + H331 Toxic in contact with skin or if inhaled. H302 Harmful if swallowed. H361d Suspected of damaging the unborn child.

Precautionary statements

P264 Wash skin thoroughly after handling P280 Wear protective gloves/eye protection/face protection. P302+P352 IF ON SKIN: Wash with plenty of soap and water. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312 Call a POISON CENTER or doctor/physician if you feel unwell. P332+P313 If skin irritation persists: Get medical advice/attention. P337+P313 If eye irritation persists: Get medical advice/attention. P362 Take off contaminated clothing and wash before reuse. none P261 Avoid breathing dust/fumes/gas/mist/vapors/spray. P280 Wear protective gloves/protective clothing. P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P330 Rinse mouth. P405 Store locked up. P501 Dispose of contents/container to a licensed disposal company. P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P281 Use personal protective equipment as required. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. PP261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ protective clothing. P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P302 + P352 + P312 IF ON SKIN: Wash with plenty of water. Call a POISON CENTER/doctor if you feel unwell. P304 + P340 + P311 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor. P362 Take off contaminated clothing and wash before reuse. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant P201 Obtain special instructions before use P202 Do not handle until all safety precautions have been read and understood. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P312 + P330 IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant.

Health hazards

2 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0 1 Flammability: 0 0 Fire: 0 Reactivity Hazard: 0 2 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0 2 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0 1 Flammability: 0 4 Fire: 0 Reactivity Hazard: 0 1 Flammability: 0 1 Fire: 0 Reactivity Hazard: 0

Physical hazards

0 0 0 0 0 0

Potential health effects

PS48: Reversine: Emergency Overview Ingestion: Toxic if swallowed. Sodium butyrate: Emergency Overview Tranylcypromine Hemisulfate: Emergency Overview Valproic Acid, Sodium Salt: Emergency Overview

Hazard pictograms

none