Cytochrome P450 Reductase (CPR) Activity Kit (Colorimetric)

Hazard statements (CLP)

H227, H302, H314, H315, H318, H319, H351

Code

Statements

H227

Combustible liquid

SECTION 2: Hazards identification

OSHA Hazards Component Description Volume Safety Information CPR Assay Buffer Proprietary Buffer 50 ml No hazards G6P Standard Lyophilized 1 vial No hazards Inhibitor (Diphenyleneiodonium Chloride, 10

Contains

DMSO 100 µl See below mM) NADPH Substrate Mix Lyophilized (contains WST-8) 1 vial See below G6P Standard Developer Methoxy-PMS 1 vial See below Human CPR Positive Control Lyophilized 1 vial No hazards NOTE The safety data shown below is based on pure ingredients The amount in this kit comprises much less Methoxy-PMS: Emergency Overview

2.1 Classification of the substance or mixture

Acute toxicity, Oral (Category 4), H302 Skin irritation (Category 2), H315 Eye irritation (Category 2A), H319 Carcinogenicity (Category 2), H351 H314 Causes severe skin burns and eye damage. H318 Causes serious eye damage. Flammable liquids (Category 4)

Signal word

Warning Danger Warning

Hazard statements

H302 Harmful if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H351 Suspected of causing cancer. H314 Causes severe skin burns and eye damage H227 Combustible liquid

Precautionary statements

P201 Obtain special instructions before use P202 Do not handle until all safety precautions have been read and understood. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/ eye protection/ face protection. P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P321 Specific treatment (see supplemental first aid instructions on this label). P330 Rinse mouth. P332 + P313 If skin irritation occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant. P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray P264 Wash skin thoroughly after handling. P280 Wear protective gloves/ eye protection/ face protection If swallowed: Rinse mouth. Do NOT induce vomiting. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lens] if present and easy to do. Continue rinsing. Immediately call a poison center/doctor. P312 Call a POISON CENTER or doctor/ physician if you feel unwell. Wash contaminated clothing before reuse. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/ international regulations. none

Health hazards

2 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0 Causes serious eye irritation. Causes skin irritation. Harmful if swallowed. Material may be irritating to the mucous membranes and upper respiratory tract. May be harmful by inhalation or skin absorption. May cause respiratory system irritation. Suspected of causing cancer WST-8: Emergency Overview: *3 Flammability: 0 3 Fire: 0 Reactivity Hazard: 0 DMSO: Emergency Overview 0 Flammability: 2 0 Fire: 2 Reactivity Hazard: 0

Physical hazards

0 0

2.3 Other hazards

Combustible Liquid, Target Organ Effect Target Organs: Eyes, Skin

Potential health effects

Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed.

Medical Conditions Generally Aggravated by Exposure

Avoid contact w/DMSO solutions containing toxic materials or materials with unknown toxicological properties. DMSO is readily absorbed through skin and may carry such materials into the body.