Caspase-9 Inhibitor Drug Screening Kit

Hazard statements (CLP)

H227, H302, H315, H319, H335

Code

Statements

H227

Combustible liquid

SECTION 2: Hazards identification

NFPA Rating Component Description Volume Safety Information 2X Reaction Buffer Proprietary Buffer (contains Glycerol) 10 ml See below Caspase-9 Substrate, In DMSO 0.5 ml See below LEHD-AFC DTT Solution in H2O (1 M) 100 µl See below Active Caspase-9 Lyophilized 100 units No hazards Caspase Inhibitor, In DMSO 10 µl See below Z-VAD-FMK Glycerol: Emergency Overview

2.3 Other hazards

Target organ effect Target Organs: Kidney Combustible liquid, Target organ effect Target Organs: Eyes, Skin Target organ effect, Harmful by ingestion, Irritant Target Organs: Central nervous system

2.1 Classification of the substance or mixture

Skin irritation (Category 3) Eye irritation (Category 2B) Flammable liquids (Category 4) Acute toxicity, Oral (Category 4) Skin irritation (Category 2) Eye irritation (Category 2A)

Hazard pictograms

none none

Signal word

none Warning Warning

Hazard statements

none H227 Combustible liquid H302 Harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335: May cause respiratory irritation

Precautionary statements

P305+P351+P338 IF IN EYES Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. none P305+P351+P338 IF IN EYES Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Health hazards

1 Flammability: 1 1 Fire: 1 Reactivity Hazard: 0 0 Flammability: 2 0 Fire: 2 Reactivity Hazard: 0 2 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0

Physical hazards

0 0 0

Potential health effects

Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. DMSO: Emergency Overview Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed. Inhalation: May be harmful if inhaled. Causes respiratory tract irritation. Skin: May be harmful if absorbed through skin. Causes skin irritation. Eyes: Causes eye irritation. Ingestion: Harmful if swallowed.

Medical Conditions Generally Aggravated by Exposure

Avoid contact w/DMSO solutions containing toxic materials or materials with unknown toxicological properties. DMSO is readily absorbed through skin and may carry such materials into the body. DTT: Emergency Overview