Caspase-3/CPP32 Fluorometric Assay Kit

Hazard statements (CLP)

H227, H302, H315, H316, H319, H320, H335

Code

Statements

H227

Combustible liquid

SECTION 2: Hazards identification

NFPA Rating Component Description Volume Safety Information K105-25: 25 ml Cell Lysis Buffer Proprietary Buffer (contains Triton X-100 & DTT) K105-100: 100 ml See below K105-200: 100 ml K105-400: 100 ml K105-25: 2 ml 2X Reaction Buffer Proprietary Buffer K105-100: 4 x 2 ml No hazards K105-200: 16 ml K105-400: 32 ml K105-25: 125 µl DEVD-AFC In DMSO (1 mM) K105-100: 500 µl See below K105-200: 2 x 0.5 ml K105-400: 2 x 1 ml K105-25: 100 µl DTT Solution in H2O (1 M) K105-100: 400 µl See below K105-200: 400 µl K105-400: 400 µl Triton X-100: Emergency Overview

2.3 Other hazards

Irritant, Harmful by ingestion Target organ effect, Harmful by ingestion, Irritant Target Organs: Central nervous system Combustible Liquid, Target Organ Effect Target Organs: Eyes, Skin

2.1 Classification of the substance or mixture

Serious eye damage (Category 1) Skin irritation (Category 3) Acute aquatic toxicity (Category 3) Chronic aquatic toxicity (Category 3) Acute toxicity, Oral (Category 4) Skin irritation (Category 2) Eye irritation (Category 2A) Flammable liquids (Category 4)

Signal word

Warning Warning Warning

Hazard statements

H302: Harmful if swallowed H316 Causes mild skin irritation. H320: Causes eye irritation H302 Harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335: May cause respiratory irritation H227 Combustible liquid

Precautionary statements

P261 Avoid breathing dust/fumes/gas/mist/vapors/spray P264 Wash hands thoroughly after handling. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/container to an approved waste disposal plant. P305+P351+P338 IF IN EYES Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. none

Health hazards

2 Flammability: 1 2 Fire: 1 Reactivity Hazard: 0 2 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0 0 Flammability: 2 0 Fire: 2 Reactivity Hazard: 0

Physical hazards

0 0 0

Potential health effects

Inhalation: May be harmful if inhaled. Causes respiratory tract irritation. Skin: Harmful if absorbed through skin. Causes skin irritation. Eyes: Causes eye irritation. Ingestion: Harmful if swallowed. DTT: Emergency Overview Inhalation: May be harmful if inhaled. Causes respiratory tract irritation. Skin: May be harmful if absorbed through skin. Causes skin irritation. Eyes: Causes eye irritation. Ingestion: Harmful if swallowed. DMSO: Emergency Overview Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed.

Hazard pictograms

none

Medical Conditions Generally Aggravated by Exposure

Avoid contact w/DMSO solutions containing toxic materials or materials with unknown toxicological properties. DMSO is readily absorbed through skin and may carry such materials into the body.