Caspase-3/CPP32 Colorimetric Assay Kit

Hazard statements (CLP)

H227, H303, H315, H317, H319, H335, H400, H410

Code

Statements

H227

Combustible liquid

SECTION 2: Hazards identification

OSHA Hazards Component Description K106-25 K106-100 K106-200 K106-400 Safety Information Cell Lysis Buffer Proprietary (contains Tergitol) 25 ml 100 ml See Below 2X Reaction Buffer Proprietary (contains Glycerol 2 ml 4 x 2 ml 16 ml 32 ml See Below and CHAPS) DEVD-pNA (4 mM)

Contains

DMSO 125 µl 0.5 ml 2 x 0.5 ml 2 x 1 ml See Below DTT (1 M) Liquid 100 µl 0.4 ml See below Dilution Buffer Liquid (containsGlycerol and 25 ml 100 ml 200 ml 400 ml See Below Tergitol) Tergitol: Emergency Overview

2.1 Classification of the substance or mixture

Skin irritation (Category 2), H315 Skin sensitization (Sub-category 1A), H317 Short-term (acute) aquatic hazard (Category 1), H400 Long-term (chronic) aquatic hazard (Category 1), H410 Skin irritation (Category 3) Eye irritation (Category 2B) Skin irritation (Category 2), H315 Eye irritation (Category 2A), H319 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335 Acute toxicity, Oral (Category 5) Skin irritation (Category 2) Eye irritation (Category 2A) Flammable liquids (Category 4)

Signal word

Warning none Warning Warning Warning

Hazard statements

H315 Causes skin irritation. H317 May cause an allergic skin reaction. H410 Very toxic to aquatic life with long lasting effects. none H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. H303 May be harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H227 Combustible liquid

Precautionary statements

P261 Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray P264 Wash skin thoroughly after handling. P272 Contaminated work clothing must not be allowed out of the workplace. P273 Avoid release to the environment. P280 Wear protective gloves. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P333 + P313 If skin irritation or rash occurs: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. P391 Collect spillage. P501 Dispose of contents/ container to an approved waste disposalplant P305+P351+P338 IF IN EYES Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P261 Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ eye protection/ face protection. P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312 Call a POISON CENTER or doctor/ physician if you feel unwell. P321 Specific treatment (see supplemental first aid instructions on this label). P330 Rinse mouth. P332 + P313 If skin irritation occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant. P305+P351+P338 IF IN EYES Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. none

Health hazards

0 Flammability: 0 0 Fire: 0 Reactivity hazard: 0 1 Flammability: 1 1 Fire: 1 Reactivity Hazard: 0 2 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0 2 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0 0 Flammability: 2 0 Fire: 2 Reactivity Hazard: 0

Physical hazards

0 0 0 0 0

Potential health effects

Inhalation: May be harmful if inhaled. Material is irritating to the tissue of the mucous membranes and upper respiratory tract.Harmful; if inhaled. May cause allergy or asthma symptoms or breathing difficulties. Skin: May be harmful if absorbed through skin. May cause an allergic skin reaction. Eyes: Causes eye irritation. Ingestion: Harmful if swallowed. To the best of our knowledge, the toxicological properties have not been thoroughly investigated Glycerol: Emergency Overview Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed. CHAPS: Emergency Overview: Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: Harmful if absorbed through skin. May cause skin irritation. Eyes: Cause eye irritation. Ingestion: Harmful if swallowed. DTT: Emergency Overview Inhalation: May be harmful if inhaled. Causes respiratory tract irritation. Skin: May be harmful if absorbed through skin. Causes skin irritation. Eyes: Causes eye irritation. Ingestion: Toxic if swallowed. DMSO: Emergency Overview Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed.

2.3 Other hazards

Target Organ Effect Target Organs: Kidney Target Organ Effect, Toxic by ingestion, Irritant Target Organs: Central nervous system Combustible liquid, Target organ effect Target Organs: Eyes, Skin

Hazard pictograms

none

Medical Conditions Generally Aggravated by Exposure

Avoid contact w/DMSO solutions containing toxic materials or materials with unknown toxicological properties. DMSO is readily absorbed through skin and may carry such materials into the body.