Acetylcholinesterase Inhibitor Screening Kit

Hazard statements (CLP)

H227, H301, H301+H311, H311, H315, H319, H335

Code

Statements

H227

Combustible liquid

SECTION 2: Hazards identification

NFPA Rating Component Description Volume Safety Information AChE Assay Buffer Liquid 50 ml No hazards AChE Substrate

Contains

AChE Substrate 1 vial See below Acetylcholinesterase Liquid 1 vial No hazards Probe Mix DTNB 1 vial See below Donepezil (10 mM) In DMSO 20 µl See below DTNB: Emergency Overview

2.3 Other hazards

Irritant Combustible Liquid, Target Organ Effect Target Organs: Eyes, Skin

2.1 Classification of the substance or mixture

Skin irritation (Category 2) Eye irritation (Category 2A) Specific target organ toxicity – single exposure (Category 3) Acute toxicity, Oral (Category 3), H301 Acute toxicity, Dermal (Category 3), H311 Skin irritation (Category 2), H315 Eye irritation (Category 2A), H319 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335 Flammable liquids (Category 4)

Signal word

Warning Danger Warning

Hazard statements

H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. H301 + H311 Toxic if swallowed or in contact with skin H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. H227 Combustible liquid

Precautionary statements

P261 Avoid breathing dust/fumes/gas/mist/vapors/spray P264 Wash hands thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection. P302+P352 IF ON SKIN: Wash with plenty of soap and water. P304+P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P332+P313 If skin irritation occurs: Get medical advice/attention. P337+P313 If eye irritation persists: Get medical advice/attention. P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ eye protection/ face protection. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312 Call a POISON CENTER or doctor/ physician if you feel unwell. P322 Specific measures (see supplemental first aid instructions on this label). P330 Rinse mouth. P332 + P313 If skin irritation occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P361 Remove/Take off immediately all contaminated clothing. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant. none

Health hazards

2 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0 2 Flammability: 0 2 Fire: 0 Reactivity Hazard: 0 0 Flammability: 2 0 Fire: 2 Reactivity Hazard: 0

Physical hazards

0 0 0

Potential health effects

Inhalation: May be harmful if inhaled. Causes respiratory tract irritation. Skin: May be harmful if absorbed through skin. Causes skin irritation. Eyes: Causes eye irritation. Ingestion: May be harmful if swallowed. AChE Substrate: Emergency Overview Inhalation: Toxic if inhaled. Material is extremely destructive to the tissue of the mucous membranes and upper respiratory tract. Skin: Toxic if absorbed through skin. Causes skin burns. Eyes: Causes eye burns. Ingestion: Toxic if swallowed. DMSO: Emergency Overview Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed.

Hazard pictograms

none

Medical Conditions Generally Aggravated by Exposure

Avoid contact w/DMSO solutions containing toxic materials or materials with unknown toxicological properties. DMSO is readily absorbed through skin and may carry such materials into the body.