20S Immunoproteasome Activity Assay Kit (Fluorometric)

Hazard statements (CLP)

H227, H228, H302, H302+H332, H315, H318, H319, H332, H335, H401, H402, H412

Code

Statements

H227

Combustible liquid

SECTION 2: Hazards identification

NFPA Rating Components Description Volume Safety Information 20S IP Assay Buffer

Contains

EDTA and SDS 25 ml See Below 20S IP Substrate DMSO 200 μl See Below 20S IP Positive Control TCEP and BSA 20 µl See Below AMC Standard DMSO 100 µl See Below 20S IP Inhibitor DMSO 100 µl See Below DMSO: Emergency Overview

2.3 Other hazards

Combustible liquid, Target organ effect Target Organs: Eyes, Skin

2.1 Classification of the substance or mixture

Flammable liquids (Category 4) Eye irritation (Category 2A), H319 Short-term (acute) aquatic hazard (Category 3), H402 Flammable solids (Category 2), H228 Acute toxicity, Oral (Category 4), H302 Acute toxicity, Inhalation (Category 4), H332 Skin irritation (Category 2), H315 Serious eye damage (Category 1), H318 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335 Short-term (acute) aquatic hazard (Category 2), H401 Long-term (chronic) aquatic hazard (Category 3), H412 Skin irritation (Category 2), H315 Eye irritation (Category 2A), H319 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335 Acute Toxicity; Oral, Category 4

Signal word

Warning Warning Danger Warning Warning

Hazard statements

H227 Combustible liquid H319 Causes serious eye irritation. H402 Harmful to aquatic life. H228 Flammable solid. H302 + H332 Harmful if swallowed or if inhaled. H315 Causes skin irritation. H318 Causes serious eye damage. H335 May cause respiratory irritation. H401 Toxic to aquatic life. H412 Harmful to aquatic life with long lasting effects. H315 Causes skin irritation. H319 Causes serious eye irritation. H302: Harmful if swallowed.

Precautionary statements

none P264 Wash skin thoroughly after handling P273 Avoid release to the environment. P280 Wear eye protection/ face protection. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes.Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 If eye irritation persists: Get medical advice/ attention. P501 Dispose of contents/ container to an approved waste disposal plant. P210 Keep away from heat/sparks/open flames/hot surfaces. No smoking P240 Ground/bond container and receiving equipment. P241 Use explosion-proof electrical/ ventilating/ lighting equipment. P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P280 Wear protective gloves/ eye protection/ face protection. P301 + P312 + P330 IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 + P312 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P305 + P351 + P338 + P310 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. P332 + P313 If skin irritation occurs: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. P370 + P378 In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposalplant. P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray P264 Wash skin thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ eye protection/ face protection. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 + P312 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P332 + P313 If skin irritation occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant P264 Wash {hands} thoroughly after handling P301+312 IF SWALLOWED Call a POISON CENTER or doctor/physician if you feel unwell P330: Rinse mouth. Adverse Human Health: Harmful if swallowed. Effects and Symptoms: Material may be irritating to the mucous membranes and upper respiratory tract. May be harmful by inhalation or skin absorption. May cause eye, skin, or respiratory system irritation. To the best of our knowledge, the toxicological properties have not been thoroughly investigated

Health hazards

0 Flammability: 2 0 Fire: 2 Reactivity Hazard: 0 Flammability: Fire: Reactivity Hazard: Flammability: Fire: Reactivity Hazard: Flammability: Fire: Reactivity Hazard: 1 Flammability: 0 1 Fire: 0 Reactivity Hazard: 0

Physical hazards

0 0

Potential health effects

Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed. Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed. Sodium dodecyl sulfate (SDS): Emergency Overview Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed. Tris(2-carboxyethyl)phosphine hydrochloride solution) TCEP: Emergency Overview Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed. Bovine Serum Albumin (BSA): Emergency Overview: Inhalation: May be harmful by inhalation. Material may be irritating to the mucous membranes and upper respiratory tract. Skin: Harmful if absorbed through skin. May cause skin irritation. Eyes: Cause eye irritation. Ingestion: Harmful if swallowed

Medical Conditions Generally Aggravated by Exposure

Avoid contact w/DMSO solutions containing toxic materials or materials with unknown toxicological properties. DMSO is readily absorbed through skin and may carry such materials into the body EDTA: Emergency Overview