General Information
Revision date
2018-03-22
Product name
Cercosporamide, from microbial source
Product Synonyms
(9aS)-8-acetyl-1,3,7-trihydroxy-9a-methyl-9-oxodibenzofuran-4-carboxamide
CAS No.
131436-22-1
Icons in SDS
Company Information
company name
BIOMAR MICROBIAL TECHNOLOGIES
e-mail address of the competent person responsible for the Safety Data Sheet
info@biomarmt.com
Section 2
Other physicochemical hazards
Cercosporamide was originally identified as a host-selective phytotoxin and broad, spectrum antifungal agent isolated from Cercosporidium henningsii. More recently, cercosporamide was shown to inhibit a cell wall integrity pathway mediated through a serine/threonine protein kinase, Pkc1, that is central to cell wall biosynthesis. It is both a potent (IC50<50nM) ans selective inhibitor of Pkc1 kinase.
Health hazards
To the best of our knowledge, the health hazards of this material have not been fully investigated.
