Note: Ingredients listed on restricted chemical lists
EC/CAS
215-185-5/1310-73-2
Name of the chemical
sodium hydroxide
Concentration
5-7% 0.1-1% 0.1-1%
EC/CAS
201-069-1/77-92-9
Name of the chemical
Citric acid
Concentration
10-13%
EC/CAS
231-633-2/7664-38-2
Name of the chemical
phosphoric acid
Concentration
5-7%
General Information
Revision date
2015-10-07
Product name
ISOLATE II RNA/DNA/Protein Kit
Icons in SDS
Company Information
company name
Bioline Reagents Ltd
e-mail address of the competent person responsible for the Safety Data Sheet
info.uk@bioline.com, info.de@bioline.com, info.us@bioline.com, info.aust@bioline.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H302, H312, H317, H331, H332, H334, H412
Hazard statements
Code
Statements
H302
Harmful if swallowed
Section 2
SECTION 2: Hazards identification
According to European Directive 67/548/EEC as amended Product name Directive 1999/45/EC GHS Directive 1272/2008/EC Protein Loading dye Does not need labelling as Does not need labelling as hazardous hazardous Protein Binding Buffer HARMFUL WARNING H302 – Acute Tox. 4 oral R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. S22-26-36/37 – Do not breathe dust Protein Elution Buffer Does not need labelling as Does not need labelling as hazardous hazardous Protein Neutralization Buffer Does not need labelling as Does not need labelling as hazardous hazardous DNA Elution Buffer Does not need labelling as Does not need labelling as hazardous hazardous RNA Elution Buffer Does not need labelling as Does not need labelling as hazardous hazardous Wash Buffer W1 Does not need labelling as Does not need labelling as hazardous hazardous DNase I Reaction Buffer DRB Does not need labelling as Does not need labelling as hazardous hazardous Lysis Buffer TX Does not need labelling as DANGER hazardous H302 – Acute Tox. 4 oral H312 – Acute Tox. 4 dermal H332 – Acute Tox. 4 inhale H412 – Chronic Tox. aquatic life EUH032 – Contact with acids liberates very toxic gas DNase I Solution HARMFUL WARNING R42/43 – May cause H317 – Skin Sens. 1A/1B sensitisation by inhalation H334 – Resp. Sens. 1A/1B and skin contact Wash Buffer W2 Does not need labelling as Does not need labelling as hazardous hazardous Wash Buffer W3 HARMFUL WARNING H302 – Acute Tox. 4 oral R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. S22-26-36/37 – Do not breathe dust According to Regulation (EC) No1272/2008 Skin Sensitivity (Category 1A/1B) Respiratory Sensitivity (Category 1A/1B) Acute Toxicity, Oral (Category 4) Eye Irritant (Category 2) Specific Target Organ Toxicity – Single Exposure (Category 3) According to European Directive 67/548/EEC as amended. C – Corrosive. Xn – Harmful. Xi – Irritant. Irritating to eyes. May cause sensitisation by inhalation and skin contact.
Signal word
Warning
Hazard statements
H302 Harmful if swallowed. H312 Harmful in contact with skin. H317 May cause an allergic skin reaction H331 Toxic if inhaled. EUH032 Contact with acids liberates very toxic gas. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H412 Harmful to aquatic life with long lasting effects.
Precautionary statements
P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P302+352 IF ON SKIN: Wash with plenty of soap and water. P304+341 IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. P333+313 If skin irritation or rash occurs: Get medical advice/attention. P342+311 If experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. P363 Wash contaminated clothing before reuse.
Hazard pictograms
Xi Irritant Xn Harmful C Corrosive
R-phrase(s)
R20/21/22 Harmful by inhalation, in contact with skin and if swallowed. R32 Contact with acids liberates very toxic gas. R34 Causes burns. R36 Irritating to eyes. R42/43 May cause sensitization by inhalation and skin contact. R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
S-phrase(s)
S22 Do not breathe dust. S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (Show the label where possible). S61 Avoid release to the environment.
2.3 Other hazards
None