Note: Ingredients listed on restricted chemical lists
EC/CAS
200-002-3/50-01-1
Name of the chemical
Guanidinium chloride
Concentration
60-100%
EC/CAS
200-311-3/57-09-0
Name of the chemical
hexadecyltrimethylammonium bromide
Concentration
5% 0.1-1% 0.1-1% 0.1-1%
General Information
Revision date
2015-10-07
Product name
ISOLATE II Plant microRNA Kit
Icons in SDS
Company Information
company name
Bioline Reagents Ltd
e-mail address of the competent person responsible for the Safety Data Sheet
info.uk@bioline.com, info.de@bioline.com, info.us@bioline.com, info.aust@bioline.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H302, H312, H315, H317, H318, H332, H334, H335, H400, H410, H412
Hazard statements
Code
Statements
H302
Harmful if swallowed
Section 2
SECTION 2: Hazards identification
According to European Directive 67/548/EEC as amended Product name Directive 1999/45/EC GHS Directive 1272/2008/EC RNA Elution Buffer Does not need labelling as hazardous Wash Buffer W1 Does not need labelling as hazardous DNase I Reaction Does not need labelling as Buffer DRB hazardous Lysis Buffer RPX Does not need labelling as WARNING hazardous H302 – Acute Tox. 4 oral H312 – Acute Tox. 4 dermal H315 – Irritant dermal H318 – Dermal allergen H332 – Acute Tox. 4 inhale H335 – Irritant inhale H400 – Very Tox. Aquatic life H410 – Very Tox. Aquatic life, long lasting H412 – Aquatic Chronic 3 DNase I Solution HARMFUL WARNING R42/43 – May cause H317 – Skin Sens. 1A/1B sensitisation by inhalation and H334 – Resp. Sens. 1A/1B skin contact According to Regulation (EC) No1272/2008 Skin Sensitivity (Category 1A/1B) Respiratory Sensitivity (Category 1A/1B) Acute Toxicity, Oral (Category 4) Serious eye damage (Category 1) Specific Target Organ Toxicity – Single Exposure (Category 3) Acute aquatic toxicity (Category 1) Chronic aquatic toxicity (Category 1) According to European Directive 67/548/EEC as amended. C – Corrosive. Xn – Harmful. Xi – Irritant. N – Dangerous for the environment
Signal word
Warning
Hazard statements
H302 Harmful if swallowed H312 Harmful in contact with skin H315 Causes skin irritation H317 May cause an allergic skin reaction H318 Causes serious eye damage H332 Harmfulc if inhaled H335 May cause respiratory irritation H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled H400 Harmful to aquatic life with long lasting effects H410 Very toxic to aquatic life with long lasting effects H412 Harmful to aquatic life with long lasting effects
Precautionary statements
P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing. P302+352 IF ON SKIN: Wash with plenty of soap and water. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P333+313 If skin irritation or rash occurs: Get medical advice/attention. P342+311 If experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. P363 Wash contaminated clothing before reuse.
Hazard pictograms
Xi Irritant Xn Harmful C Corrosive N Dangerous for the environment
R-phrase(s)
R20/21/22 Harmful by inhalation, in contact with skin and if swallowed. R34 Causes burns. R36/37/38 Irritating to eyes, respiratory system and skin. R41 Risk of serious damage to eyes. R42/43 May cause sensitization by inhalation and skin contact. R50/52/53 Toxic to aquatic organisms, may cause long- term adverse effects in the aquatic environment.
S-phrase(s)
S22 Do not breathe dust. S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).. S61 Avoid release to the environment.
2.3 Other hazards
None