Human Magnetic Luminex Screening Assay

Hazard statements (CLP)

H317

Code

Statements

H317

May cause an allergic skin reaction

SECTION 2: Hazards identification

Precautionary statements

P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P272: Contaminated work clothing should not be allowed out of the workplace. P280: Wear protective gloves.

Response

IF ON SKIN Wash with plenty of soap and water. If skin irritation or rash occurs get medical attention. Wash contaminated clothing before reuse.

EU Classification

Directive 67/548/EEC The product is classified as a skin sensitizer according to Directive 1999/45/EC and its amendments. Hazard Symbol / R-Phrase / S-Phrase R43 May cause sensitization by skin contact. S36/37 Wear Suitable protective clothing and gloves

2.3 Other hazards

none none 3. Information on Ingredients: Description: ProClin 300

Contains

CAS No. EC-No. Index-No. Modified Alkyl Carboxylate - <0.01% Mixture of 5-Chloro-2-Methyl-4- 55965-84-9 - 613-167-00-5 <0.01% Isothiazolin-3-One (26172-55-4) and 2- Methyl-4-Isothiazolin-3-One (2682-20-4) Modified Glycol - ≤1.6% 4. First Aid Measures:  IF IN EYES: Rinse thoroughly with water for at least 15 minutes and immediately consult a physician.  IF ON SKIN (or hair): Immediately take off contaminated clothing or shoes. Wash with plenty of soap and water. Consult a physician.  IF INHALED: If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.  IF SWALLOWED: Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Immediately consult a physician. 5. Fire Fighting Measures:  Suitable extinguishing agents: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.  Special precautions for fire-fighters: Self contained breathing apparatus and full protective clothing must we worn in case of fire. 6. Accidental Release Measures:  Person-related safety precautions: Use appropriate personal protective equipment to prevent contamination of skin, eyes and personal clothing. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas.  Measures for environmental protection: Keep away from drains.  Measures for containment and cleaning: Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. 7. Handling and Storage:  Precautions for safe handling: Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Use normal measures for preventive fire protection.  Conditions for safe storage: Store in a cool, dry place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. 8. Exposure Controls and Personal Protection:  Control parameters: Contains no substances with occupational exposure limit values.  Individual protection measures: Wash hands thoroughly after handling chemical products and before eating, smoking or using the toilet. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Eye/face protection: Wear approved safety goggles. Skin/hand protection: Handle with protective gloves, plastic or rubber. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. Body protection: Wear suitable protective clothing as protection against splashing or contamination. Other skin protection: Appropriate footwear and any additional skin protection measures should be selected based on the task being performed and the risks involved. Respiratory protection: In case of inadequate ventilation, use a suitable respirator. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). 9. Physical and Chemical Properties:  Appearance: Clear Liquid  Upper/lower flammability or explosive limits: Not available  Odor: Not available  Vapor density Not available  Odor threshold: Not available  Vapor pressure: Not available  pH: Not available  Relative density: 1.03 g/cm3  Melting point/freezing point: -40º C  Solubility in/Miscibility with Water: Soluble  Boiling point/Boiling range: 189º C Partition coefficient noctanol/water Not available  Flash point: 118º C – closed cup  Auto igniting: Not available  Evaporation rate: Not available  Decomposition temperature: Not available  Flammability (solid, gas): Not available  Viscosity: Not available 10. Stability and Reactivity:  Chemical Stability: Stable under recommended storage conditions.  Conditions to avoid: Strong oxidizing agents, reducing agents, Amines, Mercaptans  Hazardous decomposition products: Hazardous decomposition products formed under fire conditions – Carbon oxides, nitrogen oxides (NOx), Sulphur oxides, Hydrogen chloride gas.

TOXICOLOGICAL INFORMATION

 Acute toxicity: LD50 Oral – rat – 862 mg/kg LD50 Dermal – rabbit- 2800 mg/kg  Skin corrosion/irritation: Can cause severe burns. Skin – rabbit – Corrosive  Serious eye damage/irritation: Rabbit – Corrosive to eyes  Respiratory or skin sensitization: May cause allergic skin reaction.  Germ cell mutagenicity: No data available  Carcinogenicity: No data available  Reproductive toxicity: No data available  Specific target organ toxicity (STOT) -single exposure: No data available  Specific target organ toxicity (STOT) -repeated exposure: No data available

Aspiration hazard

Can cause severe burns  Information on likely routes of exposure: Routes of entry anticipated; oral, dermal, inhalation.  Symptoms related to the physical, chemical and toxicological characteristics: Inhalation: Harmful if inhaled. Material is extremely destructive to the tissue of the mucous membranes and upper respiratory tract. Ingestion: Harmful if swallowed. Causes burns. Skin contact: Harmful if absorbed through skin. Causes burns. Eye contact: Causes eye burns.  Delayed and immediate effects and also chronic effects from short and long term exposure: Short term exposure Potential immediate effects Not available. Potential delayed effects Not available Long term exposure Potential immediate effects Not available. Potential delayed effects Allergic contact dermatitis  Effects of chronic exposure: Proclin 300 at levels greater than or equal to 0.1% is not identified as probable, possible or a confirmed human carcinogen by IARC.  Numerical measures of toxicity: Not available

Further information

NA  Notice to reader: To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.

ECOLOGICAL INFORMATION

 Ecotoxicity: No data available  Biodegradability: No data available.  Bioaccumulative potential: No data available.  Mobility in soil: No data available.

Other hazards

Toxic to aquatic organisms

Disposal

Considerations  Disposal methods: Dispose of waste in accordance to applicable national, regional, or local regulations.  Contaminated packaging: Dispose in the same manner as unused product.  Special precautions: Dispose of small amounts of spilled material as described in section 6. Large spills must be dealt with separately by qualified disposal personnel. Avoid dispersal of spilt material to soil, waterways, drains and sewers. 14. Transportation Information

UN Number

None DOT regulations

Hazard categories

None  Land transport ADR/RID (cross-border): Not regulated.  Maritime transport IMDG: Not regulated.  Marine pollutant: No  Air transport ICAO-TI and IATA-DGR: Not regulated.  Transport/Additional information: Not dangerous according to the above specifications. 15. Regulations:  US Federal and State Regulations  Toxic Substances Control Act: On TSCA Inventory  SARA 313 Components: Not listed  SARA 311/312 Hazards: Acute Health Hazard

Principle Routes of Exposure

Inhalation; ingestion or skin IF EXPOSED OR CONCERNED: Get medical advice/attention.

2.1 Classification of the substance or mixture

Some components indicated above contain ProClin 300: Skin Sens. 1; H317: May cause an allergic skin reaction.