Kallestad Spectrophotometric Function Standards A-E

SECTION 2: Hazards identification

HAZARDOUS COMPONENTS (2) HMIS Hazard Rating: This test kit should be handled only by qualified personnel trained in laboratory procedures and familiar with their potential hazards. Specific warnings are given in the instructions for use. The absence of a specific warning should not be interpreted as an indication of safety. Component

Contains

Kallestad Spec. Function - Phosphate buffered saline solution (pH 7). Standard A, 2.5 mL 0.1% Tartrazine, (FD&C Yellow #5, Acid Yellow 23) , CAS# 1934-21-0, Standard B, 2.5 mL EINECS/ELINCS No: 217-699-5; S24-36/37 (1999/45/EC– dilution < 1%). Standard C, 2.5 mL - Preserved with 0.5% sodium azide [NaN3], EINECS/ELINCS No: 247-852-1 and CAS# Standard D, 2.5 mL 26628-22-8; Xn: Harmful; R 22; S 24-35-37 (1999/45/EC– dilution < 1%, but ≥ 0.1%). Standard E, 2.5 mL HAZARDOUS COMPONENTS (3) The following information is furnished for those kit hazardous constituents that require regulatory control or disclosure at the concentration found in the kit. Note that the information here is often based on data from the chemical raw material (LD50, exposure limits, etc.). The kit contains a significantly diluted concentration in an aqueous solution, thus the assessment below has taken hazard reduction processing into consideration when possible. The EU classification was made according to the latest editions of the EU lists, and expanded upon from company and literature data. Chemical Ingredient Chemical Data / Information CAS# 26628-22-8 (100%) + EINECS/ELINCS No: 247-852-1 (100%) + Sodium azide RTECS# VY8050000 (100%) Flash Point: NE [0.5% NaN3] LD50 (oral-rat): 27 mg/kg (100%) + LC50 (inhalation-rat): 37 mg/m3 (100%) + PEL/TLV: 0.3 mg/m3 (ceiling)(100%) + IATA/DOT ID: UN1687 (undiluted, 100%) +

HMIS CODES

H=2, F=0, R=1 ++ RCRA Code: P105 (undiluted, 100%) +

EU Classification

Harmful (Xn); R 22; S 24-35-37 (< 1% and ≥ 0.1%) ++ Sodium azide, a biocidal preservative, is harmful if swallowed; it has been evident to kill at low concentrations, if enough is ingested (more than supplied in kit). May cause eye, skin or tissue irritation. Avoid contact. If swallowed, seek medical advice immediately. Sodium azide may react with lead or copper plumbing to form highly explosive metal azides; build-up in metal plumbing has led to laboratory explosions, so flush with copious water when pouring dilute solutions down the drain to prevent such explosive build-up. This material and its container must be disposed of in a safe way and in accordance with local, regional and national regulation. Handle appropriately with the requisite Good Laboratory Practices and Universal Precautions. + The kit concentration was not tested; the values refer to the solution concentration as tested, designated by percentage within parentheses. ++ The kit concentration was tested or the values given were estimated for the general diagnostic laboratory usage of the kit reagent dilution. NE: Not Established or Unknown (unable to locate data). Abbreviations for component HMIS hazard ratings are as follows: H=Health, F=Flammability, R=Reactivity General Kit Composite Health Hazards: ♦ No significant adverse health effects are expected by any route for the following chemical constituents in the kit volumes and concentrations present [dilution not subject to EU Directive labeling] Dilute (< 0.1%) Tartrazine (FD&C Yellow #5, Acid Yellow 23) , CAS# 1934-21-0, EINECS/ELINCS No 217-699-5; S24-36/37 (1999/45/EC– dilution < 1%). ♦ No significant adverse health effects are expected by any route for the miscellaneous salts, buffers, water, in the kit volumes and/or concentrations present. ♦ According to the concept of Universal Precautions (29 CFR 1910.1030), all human blood and certain human body fluids must be treated as if known to be infectious for HIV, HBV and other bloodborne pathogens. No known test method can offer complete assurance that products derived from human blood will not transmit infection; thus, they should be handled as though they contain infectious agents. Furthermore, individual patient samples being tested represent a heightened, unknown hazard. Aerosolization/inhalation, contact and mucous membrane exposure should be avoided during sample and kit handling. Consider equipment that potentially comes in contact with human source material as contaminated until appropriately decontaminated. EMERGENCY FIRST AID MEASURES (4)