Kallestad Evans Blue Counterstain

SECTION 2: Hazards identification

HAZARDOUS COMPONENTS (3) The following information is furnished for those product hazardous constituents that require regulatory control or disclosure at the concentration found in the product. Note that the information here is often based on data from the chemical raw material (LD50, exposure limits, etc.) and that the product typically contains a significantly diluted concentration in an aqueous solution; thus, the assessment below has taken hazard reduction processing into consideration when possible. The GHS and EU classifications were made according to the latest editions, and expanded upon from company and literature data. (Refer to the Key below.) Chemical Ingredient Data / Information Sodium Azide CAS# 26628-22-8 (100%) + RTECS# VY8050000 (100%) [0.1%] EC No: 247-852-1 (100%) + 1.3 Chemical Formula: NaN3 (100%) + Flash Point: NE LD50 (oral-rat): 27 mg/kg (100%) + LC50 (inhalation-rat): 37 mg/m3 (100%) + WARNING PEL/TLV: 0.3mg/m3 (ceiling)(100%) + IATA/DOT ID UN1687, Class 6.1 (undiluted, 100%) + / IATA/DOT ID NE (dilution) ++ HMIS codes: H=2, F=0, R=1 ++ RCRA Code: P105 (undiluted, 100%) + EU Classification per 1999/45/EC Harmful Xn; R 22; S 24-35-37 (< 1% and  0.1%) ++ GHS / 2008/1272/EC Classification: WARNING; H303, H313; P312 ++ Sodium azide, a biocidal preservative, may be harmful if swallowed [H303]; it has been evident to kill at low concentrations, if enough is ingested (more than supplied in kit). May be harmful in contact with skin. [H313]. May cause eye, skin or tissue irritation. May cause long lasting harmful effects to aquatic life. Avoid contact. Wash thoroughly after handling. Call a POISON CENTER or doctor/physician if you feel unwell [P312]. Avoid release to the environment. Avoid contact with metals; sodium azide may react with lead or copper plumbing to form highly explosive metal azides; build-up in metal plumbing has led to laboratory explosions, so flush with copious water when pouring dilute solutions down the drain to prevent such explosive build-up. The potential for these adverse health effects is unknown for the highly diluted, small volume of sodium azide in this kit, but is unlikely if handled appropriately with the requisite Good Laboratory Practices and Universal Precautions. This material and its container must be disposed of in a safe way and in accordance with local, regional, national and international regulations. EU Labelling Classification for 100% chemical concentration per Table 3.2 of 2008/1272/EC - from Annex I to Directive 67/548/EEC: Toxic T, Environmental Danger N R 28: Very toxic if swallowed. R 32: Contact with acids liberates very toxic gas. R 50/53: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. S (1/2-): Keep locked up and out of the reach of children. S 28: After contact with skin, wash immediately with plenty of soap and water. S 45: In case of accident or if you feel unwell, seek medical advice immediately. S 60: This material and its container must be disposed of as hazardous waste. S 61: Avoid release to the environment. Refer to special instructions/safety data sheet. Key: + The kit concentration was not tested; the values refer to the solution concentration as tested, designated by percentage within parentheses. ++ The kit concentration was tested or the values given were estimated for the general diagnostic laboratory usage of the kit reagent dilution. NE: Not Established or Unknown (unable to locate data); typically for concentrate form unless otherwise specified. Abbreviations for component HMIS hazard ratings are as follows: H=Health, F=Flammability, R=Reactivity. GHS = Globally Harmonized System RTECS # - Registry of Toxic Effects of Chemical Substances number PEL - Permissible Exposure Limit / Occupational Exposure Limit (OEL) TLV/TWA – Threshold Limit Value / Time-Weighted Average STEL - Short Term Exposure Limit IDLH - Immediately Dangerous to Life or Health Related product information:  Refer to section 2 for the full text of any GHS /2008/1272/EC statement coded above. Refer to section 16 for the full text of any Risk (R) and Safety (S) statement for the above kit component concentration.  No significant adverse health effects are expected by any route for the following chemical constituents in the kit volumes and concentrations present [dilution not subject to GHS or EU hazard labeling]:  2% Evans Blue Stain [C34H24N6O14S4  4Na], EC No 206-242-5, CAS# 314-13-6. [NOTE: This chemical has been designated by IARC with a carcinogen Classification 3, which indicates that "the Agent is NOT CLASSIFIABLE as Carcinogenic".] The chemical, physical and toxicological properties have not been thoroughly investigated.  Do not eat, drink or smoke when using this product.  Wear protective gloves/protective clothing/eye protection/face protection. Take off contaminated clothing and wash before reuse. EMERGENCY FIRST AID MEASURES (4)