UT910 FAST DRY UTHANE HARDENER - PART "B"

Potential health effects

ACUTE EXPOSURE No adverse health effects expected if the product is handled in accordance with this Safety Data Sheet and the product label. The following acute (short term) health effects may occur immediately or shortly after exposure to this product. Exposure can occur in the workplace or in the environment following releases to air, water, land, or ground water. It enters the body when breathed in with contaminated air or when consumed with contaminated food or water. Can also be absorbed through skin contact. Tolerance is reported to be acquired over the work week and lost over the weekend. Effects on human health and the environment depend on how much of the product is present and the length and frequency of exposure or the condition of the environment when exposure occurs. Repeatedly breathing large amounts of solvents, such as when "sniffing" thinner or paint, can cause permanent brain damage. As a result, humans can develop problems with speech, hearing, and vision. Humans can also experience loss of muscle control, loss of memory and decreased mental ability. Exposure to this product can also adversely affect the kidneys. High vapor concentrations are irritating to the eyes and the respiratory tract, may cause coughing, nausea, headaches and dizziness, fatigue, lethargy, anorexia, tremor, are anaesthetic and may have other central nervous system effects. Exposure to high concentrations can be fatal. Lower levels may cause trouble concentrating, headaches, and slowed reflexes. Narcotic effects occur at levels below the exposure standard. If a large amount ( > 1 ml/kg) is ingested and retained, it can cause gastrointestinal irritation, kidney damage, symptoms of CNS depression and irritation occur and may include weakness, dizziness, unconsciousness and convulsions. Vapor may cause conjunctivitis. Temporary corneal clouding may also result and may last several hours. Acute exposure may also result in narcosis, pulmonary oedema and severe kidney and liver damage. Systemic effects from short-term high exposures may include lung, kidney and brain damage. Corneal damage will occur after prolonged contact. Prolonged, repeated skin contact with low viscosity materials may de-fat the skin resulting in possible irritation and dermatitis. NOHSC has indicated that at levels above 0.5%, free organic isocyanates should be regarded as sensitizers. It is below that level in this preparation, but its presence should be noted for certain hypersensitive individuals. TARGET ORGANS : Central nervous system, eyes, skin, gastro-intestinal tract, blood, liver and kidneys ACUTE EXPOSURE (continued) SKIN Contact with the skin may result in severe irritation and drying of the skin which may lead to dermatitis if contact is prolonged. Prolonged contact may cause more severe irritation, with discomfort or pain, local redness and swelling, and possible tissue destruction. Brief contact may cause slight irritation with itching and local redness. Can be readily absorbed through the skin may cause central nervous system depression. Exposure limits with “skin” notation indicate that vapour and liquid may be absorbed through intact skin. Absorption by skin may readily exceed vapour inhalation exposure. Toxic effects may result from skin absorption. Capable of causing skin sensitisation and allergic skin reactions. Prolonged or widespread contact may result in the absorption of potentially harmful amounts of material. The material may accentuate any pre-existing skin condition. Open cuts, abraded or irritated skin should not be exposed to this material. Bare, unprotected skin should not be exposed to this material. Symptoms for skin absorption are the same as for inhalation. Contact with eyes and mucous membranes may also contribute to overall exposure and may also invalidate the exposure standard. INHALED Toxic by inhalation. Toxic effects are increased by consumption of alcohol. Repeated exposure may cause sensitisation and/or allergic reactions. Significant exposure to this chemical may adversely affect people with chronic disease of the respiratory system, skin and/or eyes. This product is a central nervous system depressant. CNS depression characterised by dizziness and headache. Central nervous system (CNS) depression may be evident early. Vapor/mist is extremely irritating to mucous membranes, upper respiratory tract and lungs. Inhalation hazard is increased at higher temperatures. Acute effects from inhalation of vapor/mist concentrations above recommended exposure levels are extremely irritating to the eyes, nose, mouth and throat, mucous membranes and the upper respiratory tract (with coughing, sneezing, nasal discomfort and discharge), could be anaesthetic and may have other central nervous system effects (characterized by headache, dizziness, increased reaction time, fatigue, loss or co-ordination, impaired judgement, lassitude, irritability), gastrointestinal disturbances (e.g. nausea, anorexia and flatulence), as well as the kidneys, the liver, and the heart. If exposure to highly concentrated solvent atmosphere is prolonged this may lead to narcosis, unconsciousness, even coma and possible death. Aspiration of liquid into lungs can cause serious (even fatal) pneumonitis. 3. continued ACUTE EXPOSURE (continued) CHRONIC EXPOSURE can occur at some time after exposure to liquid hydrocarbons and can last for months or years In view of the general properties of isocyanates, the product should be considered as involving a possible risk of irritation of the eyes, respiratory tract and respiratory sensitisation (asthma) after repeated exposure, or in sensitised persons. Inhalation of material may aggravate asthma and inflammatory or fibrotic pulmonary diseases. Prolonged or repeated skin contact causes severe irritation and may lead to de-fatting with drying, cracking, irritation and dermatitis following. Skin contact may aggravate an existing dermatitis. Can be absorbed through the skin with resultant toxic effects. Capable of causing skin sensitisation and allergic skin reactions. Repeated exposure can cause headaches, loss of appetite, nausea, and liver and kidney damage, and may cause brain damage. Evidence from animal tests indicate that repeated or prolonged solvent inhalation exposures could result in kidney disorders, nervous system impairment, liver and blood changes. [PATTYS]. Repeated exposure to this product can cause poor memory, difficulty in concentration and other brain effects. This chemical has not been adequately evaluated to determine whether brain or other nerve damage could occur with repeated exposure. However, many solvents and other petroleum based chemicals have been shown to cause such damage. Effects may include reduced memory and concentration, personality changes (withdrawal, irritability), fatigue, sleep disturbances, reduced coordination, and/or effects on nerves supplying internal organs (autonomic nerves) and/or nerves to the arms and legs (weakness, "pins and needles"). MIXED EXPOSURES Because smoking can cause heart disease, as well as lung cancer, emphysema, and other respiratory problems, it may worsen respiratory conditions caused by chemical exposure. Even if you have smoked for a long time, stopping now will reduce your risk of developing health problems. Because more than light alcohol consumption can cause liver damage, drinking alcohol can increase the liver damage caused by liquid hydrocarbons. 4 .

Medical Conditions Generally Aggravated by Exposure

Damaged skin, respiratory system disease ROUTES OF ENTRY : Ingestion, inhalation, skin contact, eye contact, absorption SWALLOWED Considered an unlikely route of entry in commercial/industrial environments. The liquid is highly irritating to mouth, throat and the gastrointestinal tract and may be toxic if swallowed in quantity. May cause corrosion and damage of the gastrointestinal tract Tends to break into a foam if the patient vomits. Ingestion can result in breathing difficulty nausea, cramps, abdominal pain &/or discomfort, vomiting, diarrhoea, central nervous system depression and other effects similar to those following inhalation. Ingestion of large amounts may lead to kidney injury, central nervous system effects and may result in red blood cell haemolysis Small amounts of liquid aspirated into respiratory system during ingestion or from vomiting may cause broncho-pneumonia or pulmonary oedema. If the victim is uncoordinated there is a greater likelihood of vomit entering the lungs and causing subsequent complications. EYE The vapour and the liquid are both severe eye irritants (experienced as discomfort or pain, excess blinking and tear production) if exposure is prolonged. The liquid is highly irritating to the eyes and is capable of causing pain and severe conjunctivitis. (marked excess redness and swelling of the conjunctiva). The liquid is capable of causing severe corneal injury and severe damage with loss of sight if not promptly and adequately treated. 3. continued

Principle Routes of Exposure

are usually by skin contact/absorption and inhalation of vapour