Cyclophosphamide for Injection, USP

Hazard statements (CLP)

H302, H315, H317, H318, H340, H350, H360, H362, H372

Code

Statements

H302

Harmful if swallowed

Signal word

Warning

Hazard statements

H302 - Harmful if swallowed H315 - Causes skin irritation H317 - May cause an allergic skin reaction H318 - Causes serious eye damage H340 - May cause genetic defects H350 - May cause cancer H360 - May damage fertility or the unborn child H362 - May cause harm to breast-fed children H372 - Causes damage to organs through prolonged or repeated exposure Xn - Harmful. R22 - Harmful if swallowed. R41 - Risk of serious damage to eyes. R45 - May cause cancer. R46 - May cause heritable genetic damage. R61 - May cause harm to the unborn child. R48/23/24/25 - Toxic: danger of serious damage to health by prolonged exposure through inhalation, in contact with skin and if swallowed.

2.1 Classification of the substance or mixture

REGULATION (EC) No 1272/2008 Acute Oral Toxicity Category 4 Skin Corrosion/Irritation Category 2 Serious Eye Damage/Eye Irritation Category 1 Skin Sensitization Category 1 Germ Cell Mutagenicity Category 1A Carcinogenicity Category 1A Reproductive Toxicity Category 1A Effects on or via lactation Specific Target Organ Toxicity (Repeated Exposure) Category 1 Ozone Not Applicable

EU Classification

Directives 67/548/EEC or 1999/45/EC

Precautionary statements

P301+ P310 - IF SWALLOWED: Immediately call a POISON CENTRE or doctor/physician P332 + P313 - If skin irritation occurs: Get medical advice/attention P362 - Take off contaminated clothing and wash before reuse P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P310 - Immediately call a POISON CENTRE or doctor/physician P261 - Avoid breathing dust/fume/gas/mist/vapors/spray P272 - Contaminated work clothing should not be allowed out of the workplace P280 - Wear protective gloves/protective clothing/eye protection/face protection P302+ P352 - IF ON SKIN: Wash with plenty of soap and water P333 + P313 - If skin irritation or rash occurs: Get medical advice/attention P321 - Specific treatment (see supplemental first aid instructions on this label) P363 - Wash contaminated clothing before reuse P263 - Avoid contact during pregnancy/while nursing P260 - Do not breathe dust/fume/gas/mist/vapors/spray P314 - Get medical attention/advice if you feel unwell P201 - Obtain special instructions before use P202 - Do not handle until all safety precautions have been read and understood P281 - Use personal protective equipment as required P308 + P313 - IF exposed or concerned: Get medical attention/advice P405 - Store locked up P264 - Wash face, hands and any exposed skin thoroughly after handling P270 - Do not eat, drink or smoke when using this product P301+ P312 - IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell P330 - Rinse mouth P501 - Dispose of contents/container to an approved waste disposal plant Obligatory Precautionary Statements P301 + P310 - IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P310 - Immediately call a POISON CENTER or doctor/physician P280 - Wear eye protection/face protection P321 - Specific treatment (see .? on this label) P202 - Do not handle until all safety precautions have been read and understood P263 - Avoid contact during pregnancy/while nursing P260 - Do not breathe dust/fume/gas/mist/vapors/spray P201 - Obtain special instructions before use P281 - Use personal protective equipment as required P308 + P313 - IF exposed or concerned: Get medical advice/attention