Note: Ingredients listed on restricted chemical lists
EC/CAS
7732-18-5
Name of the chemical
Water, distilled, conductivity or of similar purity H2O
Concentration
N/A
General Information
Revision date
2002-01-25
Product name
Prednisolone Sodium
Product Synonyms
Same
1.2.1 Relevant identified uses
for dispensing, and overpacked inside a cardboard carton
Emergency telephone
(800) 227-1427
Icons in SDS
Company Information
company name
BAUSCH & LOMB PHARMACEUTICALS, INC
Section 2
SECTION 2: Hazards identification
EMERGENCY OVERVIEW Plastic bottle in cardboard box. Clear, colorless to slightly yellow, odorless aqueous solution. Toxic by ingestion. *************************************************************************************************
Health hazards
Carcinogenicity: (NTP) No (IARC) No (OSHA) No Eye: May cause irritation or burning sensation on installation and hypersensitivity (anaphylactic) in some individuals. It has been shown, though not in humans, that through large doses or prolonged topical administration, glucocorticoids may be systemically adsorbed by pregnant mothers and produce fetal abnormalities. Systematically administered corticosteroids are secreted into breast milk in quantities not likely to have a deleterious effect on the infant. Systemic toxicity reactions include reversible hypothalamic-pituitary-adrenal axis gland suppression, manifestations of Cushing's syndrome, intercranial hypertension, hyperglycemia and glycosuria. Skin: May cause irritation and localized hypersensitivity in some individuals with itching, swelling and diffused redness of the skin. Ingestion: May cause irritation and hypersensitivity in some individuals. Large doses may induce vomiting, diarrhea, adrenal gland suppression, Cushing's syndrome, water retention, electrolyte imbalance and hyper-glycemia. Inhalation: May cause irritation and hypersensitivity in some individuals.
Potential chronic health
May cause hypersensitivity. In the presence of dermatological infections, the use of an appropriate antifungal or antibacterial agent should be instituted. Manifestations of adrenal suppression in children include linear growth retardation, delayed weight gain, low plasma cortisol levels and absence of response to ACTH stimulation. Target Organs: Eyes, skin, digestive tract, kidney and brain.
Medical Conditions Generally Aggravated by Exposure
Anaphylactic cross- reactions may occur for glucocorticoids. Preexisting conjunctival or systemic fungal infections may be aggravated. Appropriate measures should be taken if this occurs.
