285-210 Low VOC Primer

SECTION 2: Hazards identification

HMIS® ratings

Health: 2¤ Flammability: 3

Physical hazards

0 HMIS uses a numbering scale ranging from 0 to 4 to indicate the degree of hazard. A value of zero means that the substance possesses essentially no hazard; a rating of four indicates high hazard. EMERGENCY OVERVIEW WARNING FLAMMABLE LIQUID HARMFUL IF INHALED CAN CAUSE CENTRAL NERVOUS SYSTEM DAMAGE CAN CAUSE LIVER DAMAGE CAN CAUSE KIDNEY DAMAGE MAY CAUSE EYE, SKIN AND RESPIRATORY TRACT IRRITATION CONTAINS MATERIAL THAT MAY CAUSE ALLERGIC RESPIRATORY REACTION MAY CAUSE ALLERGIC OR ASTHMATIC SYMPTOMS OR BREATHING DIFFICULTIES IF INHALED. CONTAINS MATERIAL WHICH MAY CAUSE CANCER. MAY CAUSE PULMONARY EDEMA INGESTION MAY CAUSE GASTRIC DISTURBANCES

Principle Routes of Exposure

Routes of entry for solids and liquids include eye and skin contact, ingestion and inhalation. Routes of entry for gases include inhalation and eye contact. Skin contact may be a route of entry for liquefied gases. Acute toxicity: Inhalation may cause CNS depression, blurred vision, dizziness and drowsiness. Overexposure may cause nausea and vomiting. Inhalation causes headache and nausea. Intentional misuse by deliberately concentrating and inhaling this product may be harmful or fatal. Information on: 2-heptanone Inhalation of 2-heptanone (methyl amyl ketone) may lead to upper respiratory tract irritation and central nervous system effects like headache, nausea and dizziness. Information on: acetone Acute exposures to relatively large amounts of acetone can result in local effects, such as irritation to eyes, nose, throat, and respiratory tract as well as systemic effects such as central nervous system (CNS) depression, which can range in severity from lightheadedness to loss of consciousness depending on the magnitude and length of the exposure. Information on: n-butyl acetate Inhalation of butyl acetate vapors may result in headache, dizziness, nausea, irritation of the respiratory tract, and CNS depression. Prolonged inhalation exposures have been known to produce upper respiratory tract irritation and acute transient signs of reduced activity at concentrations at 1500 ppm and above in rats, with no cumulative neurotoxic effects. Overexposure may cause irritation of the eyes, nose and throat. Information on: ethyl benzene Vapors are readily absorbed through the lungs. Inhalation of ethylbenzene vapors causes drowsiness, narcosis, headaches, cramps, and tightness of the chest. Severe overexposure can cause death due to respiratory center paralysis. If aspiration occurs, chemical pneumonitis or pulmonary edema may result. Ingestion may result in kidney or liver damage. Ethyl benzene is absorbed through the skin at a low rate. Information on: kaolin Inhalation of high acute concentrations of kaolin dust may produce physical irritation. Chronic inhalation of kaolin dust may produce respiratory symptoms and may also have a fibrogenic potential. Information on: parachlorobenzotrifluoride Inhalation of Parachlorobenzotriflouride may produce symptoms of CNS depression including headache, dizziness, nausea, loss of balance and drowsiness. Ingestion may cause damage to the lining of the G.I. tract. Information on: talc Acute exposures to high concentrations of talc may produce cough, dyspnea, chest pain and weakness. Information on: wollastonite This product contains wollastonite. Inhalation may result in irritation of the mucous membranes. Cough and difficulty breathing are possible. Ingestion may result in nausea, vomiting and diarrhea. Information on: zinc oxide Inhalation of zinc dusts may result in respiratory irritation. Inhalation of zinc fumes may cause "metal fume fever". Symptoms of metal fume fever include metallic taste, dryness, and irritation of the throat, difficult breathing, weakness, fatigue and fever. Irritation: Skin contact may result in irritation, defatting and dermatitis. Vapors cause irritation to the respiratory tract and the eyes. Prolonged inhalation of product vapor can result in irritation of the mucous membranes. Information on: ethyl benzene Ethylbenzene is extremely irritating to the eyes, skin and upper respiratory tract. Eye contact may result in conjunctivitis and corneal injury. Information on: epoxy resin Prolonged or repeated contact with the eyes and skin may result in irritation. This material contains epoxy resins which may result in skin irritation or sensitization after repeated contact. Ingestion of the solid may result in gastric disturbances. Repeated dose toxicity: Information on: 2-heptanone Repeated inhalation exposures to 2-heptanone (methyl amyl ketone) have been known to produce neurological effects in experimental animals at 1000 ppm. Repeated oral exposures in rats have been known to produce liver and kidney effects at 500 mg/kg/day. Information on: acetone High doses of acetone (500 and 2500 mg/kg/day) administered by oral gavage to rats for 90 consecutive days resulted in some clinical chemistry and blood changes as well as increased absolute/relative liver and kidney weights. Histopathological examination of both organs showed acetone did not affect the liver but appeared to accentuate the kidney changes which accompany aging. No effects were observed at 100 mg/kg/day. Chronic occupational exposures to acetone at levels ranging from 300 to 100 ppm have reportedly been associated with irritation and mild CNS effects but have not affected clinical chemistry parameters or worker mortality. Information on: n-butyl acetate In a teratogenicity study, pregnant rabbits were exposed to n-butyl acetate vapors at 0 or 1500 ppm from day 1 to day 19 of gestation; pregnant rats were exposed at the same concentrations from day 1 to day 16 of gestation. Body weight changes were observed in the rats but not the rabbits. Reproductive performance was not affected. Rabbit fetus size was not affected by exposure, but fetal size in all exposed groups of rats was reduced, suggesting embryotoxicity. Information on: ethyl benzene Animal studies indicate that chronic overexposure to ethylbenzene may cause liver and kidney injury. Increased liver and kidney weight were found in rats exposed to 400 ppm for 186 days. Animal studies indicate that the vapors may be embryotoxic. Prolonged skin contact will cause edema and blistering. In NTP 2-year inhalation studies, clear evidence of carcinogenicity of ethylbenzene in male rats was noted based on increased incidences of kidney neoplasms. Incidences of testicular adenoma were also increased. In female rats, male mice and female mice there was some evidence of carcinogenicity, based on kidney adenoma, lung neoplasms and liver neoplasms, respectively. The International Agency for Research on Cancer (IARC) has classified ethylbenzene in Category 2B, sufficient evidence of carcinogenicity in animals. Information on: parachlorobenzotrifluoride Studies conducted on laboratory animals indicate that exposures to parachlorobenzotriflouride via inhalation and ingestion may result in liver and kidney damage. Information on: crystalline silica, quartz Overexposure to crystalline silica results in silicosis, a lung disease characterized by coughing, difficult breathing, wheezing, scarring of the lungs, and repeated, non-specific chest illnesses. The International Agency for Research on Cancer (IARC) has classified crystalline silica in Group 1 (those agents with evidence of carcinogenicity to humans) and National Toxicology Program (NTP) has included it in its Annual Report on Carcinogens. Information on: talc Prolonged or repeated exposure to talc can result in a form of pulmonary fibrosis (talc pneumoconiosis), possibly due to asbestos content. In a National Toxicology Program (NTP) inhalation study, talc exhibited some evidence of carcinogenicity in male rats, clear evidence in female rats and no evidence in mice. It is thought that the effects, which were reported at the high dose, were due to overburdening of the lungs. Information on: titanium dioxide IARC (International Agency for Research on Cancer) has classified this substance as group 2B (The agent is possibly carcinogenic to humans). In long-term studies in rats in which the substance was given by inhalation, a carcinogenic effect was observed. Tumors were only observed in rats after chronic inhalative exposure to high concentrations which caused sustained lung inflammation. In long-term studies in rats and mice in which the substance was given by feed, a carcinogenic effect was not observed. Dermal exposure is not expected to be carcinogenic. Information on: wollastonite This product contains wollastonite. In a lifetime inhalation study, rats exposed to 10 mg/m3 wollastonite exhibited a slightly toxic lung response; however, this was reversible after exposure was stopped. Exposure to wollastonite from this product is not anticipated unless the product is used in secondary mechanical processing operations which form dusts. Information on: zinc oxide Thirteen of nineteen workers in zinc powder factory were reported to exhibit inflammation of the upper respiratory tract after 2 to 3 years of employment. Limited studies on the developmental toxicity of zinc oxide in animals indicate that doses as high as 200 mg/kg have caused reduced fetal body weight and fetal death. ______________________________________________________________________