Xylenes, High Purity Chemicals

Hazard statements (CLP)

H226, H304, H312, H315, H319, H332, H335, H412

Code

Statements

H226

Flammable liquid and vapour

SECTION 2: Hazards identification

GHS Classification Emergency Overview: WARNING! HIGHLY FLAMMABLE LIQUID AND VAPOR. CAUSES IRRITATION TO EYES, SKIN, AND RESPIRATORY TRACT.

Aspiration hazard

IF SWALLOWED. MAY BE HARMFUL IF ABSORBED THROUGH THE SKIN OR IF INHALED. MAY CAUSE CENTRAL NERVOUS SYSTEM DEPRESSION. (Category 1) Chronic aquatic toxicity (Category 3) Eye irritation (Category 2A) Flammable Liquids (Category 3) Skin irritation (Category 2) Specific Target Organ Toxicity – single exposure (Category 3) Target Organs: Central nervous system, Eyes, Respiratory system, Skin May cause irritation of the digestive tract. May cause central nervous system depression characterized by excitement followed by nausea, headache, and unconsciousness. Advanced stages may cause collapse, loss of consciousness, coma, and death from respiratory failure. May cause affects similar to acute inhalation. Inhalation High concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness, and coma. Prolonged exposures may result in dizziness and general weakness. Irritation may lead to pneumonitis and pulmonary edema. May cause liver and kidney damage. Causes irritation of the mucous membranes. Odor is not an adequate warning of exposure to xylene. Reversible liver and kidney damage has been reported in cases of extreme overexposure. Industrial fatalities due to severe overexposure have been described. Skin May be harmful if absorbed through the skin. Causes skin irritation, defatting, cracking, and dryness. Blistering may occur, particularly if exposure is concentrated and the exposed area is covered. Liquid and vapor and be absorbed through the skin, but not as easily as inhalation or ingestion. Absorption is reported to be slow and significant health effects are not expected by this route of exposure. Chronic Prolonged or repeated exposure to xylene may cause defatting and dermatitis., reversible eye damage, labored breathing, confusion, dizziness, apprehension, memory loss, headache, tremors, weakness, anorexia, nausea, ringing in the ears, irritability, thirst, mild changes in liver function, kidney impairment, anemia, and hyperplasia (but not destruction) of bone marrow. _____________________________________________________________________________________

Classification (GHS-US)

Acute Toxicity, Dermal (Category 4) Acute Toxicity, Inhalation (Category 4)

Signal word

DANGER! .

Hazard statements

H226 Flammable liquid and vapor H304 May be fatal if swallowed and enters airways. H312 Harmful in contact with skin H315 Causes skin irritation H319 Causes serious eye irritation. H332 Harmful if inhaled H335 May cause respiratory irritation H412 Harmful to aquatic life with long lasting effects

Precautionary statements

P261 Avoid breathing dust/fumes/gas/mist/vapors P501 Dispose of contents and container to an approved waste disposal plant. P331 Do NOT induce vomiting. P303 + P361 + P353 IF ON SKIN (or hair): Remove immediately all contaminated clothing. Rinse skin with water. P310+P310 IF SWALLOWED: Immediately call a POISON CENTER or a doctor/physician. P210 Keep away from heat, sparks, open flames and hot surfaces. No smoking. P280 Wear protective gloves and eye and face protection

Potential health effects

Organ Description Eyes Contact with eyes generally causes transient superficial injury. Based on animal studies with mixed xylene isomers, it is probably a mild irritant. Ingestion