ChromaBase R Factory Packaged Colors

Potential health effects

Inhalation: May cause nose and throat irritation. May cause nervous system depression, characterized by the following progressive steps: headache, dizziness, nausea, staggering gait, confusion, unconsciousness. Reports have associated repeated and prolonged overexposure to solvents with permanent brain and nervous system damage. If this product contains or is mixed with an isocyanate activator/hardener, the following health effects may apply: Exposure to isocyanates may cause respiratory sensitization. This effect may be permanent. Symptoms include an asthma-like reaction with shortness of breath, wheezing, cough or permanent lung sensitization. This effect may be delayed for several hours after exposure. Repeated overexposure to isocyanates may cause a decrease in lung function, which may be permanent. Individuals with lung or breathing problems or prior reactions to isocyanates must not be exposed to vapors or spray mist of this product. Ingestion: May result in gastrointestinal distress. Skin or eye contact: May cause irritation or burning of the eyes. Repeated or prolonged liquid contact may cause skin irritation with discomfort and dermatitis. Other Potential Health Effects in addition to those listed above: Acetone The following medical conditions may be aggravated by exposure: lung disease, eye disorders, skin disorders. Overexposure may cause damage to any of the following organs/systems: blood, central nervous system, eyes, kidneys, liver, respiratory system, skin. Aromatic hydrocarbon The following medical conditions may be aggravated by exposure: skin disorders. Laboratory studies with rats have shown that petroleum distillates can cause kidney damage and kidney or liver tumors. These effects were not seen in similar studies with guinea pigs, dogs, or monkeys. Several studies evaluating petroleum workers have not shown a significant increase of kidney damage or an increase in kidney or liver tumors. Butyl acetate May cause abnormal liver function. The following medical conditions may be aggravated by exposure: respiratory system. Tests for embryotoxic activity in animals has been inconclusive. Rats exposed to very high airborne levels have exhibited high frequency hearing deficits. The significance of this to man is unknown. Has been toxic to the fetus in laboratory animals at doses that are toxic to the mother. Carbon black Is an IARC, NTP or OSHA carcinogen. Has shown carcinogenic activity in laboratory animals at high doses. Significance to man is unknown. The following medical conditions may be aggravated by exposure asthma, respiratory disease. WARNING This chemical is known to the State of California to cause cancer Cumene WARNING This chemical is known to the State of California to cause cancer. Ethylbenzene Is an IARC, NTP or OSHA carcinogen. Increased susceptibility to the effects of this material may be observed in people with preexisting disease of any of the following: central nervous system, kidneys, liver, lungs. Recurrent overexposure may result in liver and kidney injury. Studies in laboratory animals have shown reproductive, embryotoxic and developmental effects. WARNING: This chemical is known to the State of California to cause cancer. Heptane Increased susceptibility to the effects of this material may be observed in people with preexisting disease of any of the following: central nervous system, respiratory system, skin. May cause central nervous system effects such as dizziness, headache, nausea, and loss of consciousness. Laboratory studies with rats have shown that petroleum distillates can cause kidney damage and kidney or liver tumors. These effects were not seen in similar studies with guinea pigs, dogs, or monkeys. Several studies evaluating petroleum workers have not shown a significant increase of kidney damage or an increase in kidney or liver tumors. Aspiration may occur during swallowing or vomiting, resulting in lung damage. Hydrotreated heavy naphtha (petroleum)-A Laboratory studies with rats have shown that petroleum distillates can cause kidney damage and kidney or liver tumors. These effects were not seen in similar studies with guinea pigs, dogs, or monkeys. Several studies evaluating petroleum workers have not shown a significant increase of kidney damage or an increase in kidney or liver tumors. Hydrotreated heavy naphtha (petroleum)-B Laboratory studies with rats have shown that petroleum distillates can cause kidney damage and kidney or liver tumors. These effects were not seen in similar studies with guinea pigs, dogs, or monkeys. Several studies evaluating petroleum workers have not shown a significant increase of kidney damage or an increase in kidney or liver tumors. Isobutyl alcohol Has shown carcinogenic activity in laboratory animals at high doses. Significance to man is unknown. May cause irritation of the mucous membranes. May cause abnormal liver function. Increased susceptibility to the effects of this material may be observed in people with preexisting disease of any of the following: eyes, respiratory system, skin. Tests in laboratory animals have shown effects on any of the following organs/systems: bone marrow, liver. Prolonged skin contact may cause chemical burns. Liquid splashes in the eye may result in chemical burns. Light yellow lemon yellow oxide pigment Contact may cause skin irritation with discomfort or rash. May cause eye irritation with discomfort, tearing, or blurred vision. Melamine resin This chemical is a formaldehyde donor. Formaldehyde is an IARC, NTP or OSHA carcinogen and has shown mutagenic activity in laboratory cell culture tests. May induce pulmonary sensitization or significant irritation of the respiratory airways. Formaldehyde has produced tumors in the nasal passages of laboratory animals when exposed to high concentrations for a two year period. IARC has concluded epidemiology studies found evidence of formaldehyde related nasopharyngeal cancer in humans and have classified formaldehyde as a confirmed human carcinogen. DuPont toxicologists have reviewed these studies and classified formaldehyde as a possible human carcinogen. Methyl ethyl ketone Material is irritating to mucous membranes and upper respiratory tract. Increased susceptibility to the effects of this material may be observed in people with preexisting disease of any of the following: central nervous system, eyes, respiratory system, skin. Prolonged or repeated overexposure may cause any of the following: conjunctivitis, dermatitis. High concentrations have caused embryotoxic effects in laboratory animals. Aspiration may occur during swallowing or vomiting, resulting in lung damage. Ingestion may cause headache, nausea, vomiting, dizziness, and drowsiness. Mica Repeated or prolonged inhalation may cause any of the following: lung irritation. Long-term respiratory exposure exceeding TLV may damage the lungs, leading to bronchitis and impairment of lung capacity. Naphthenic acid, nickel salt WARNING This chemical is known to the State of California to cause cancer. Synthetic resin Skin contact may cause any of the following: irritation. Titanium dioxide Is an IARC, NTP or OSHA carcinogen. In a lifetime inhalation test, lung cancers were found in some rats exposed to 250 mg/m3 respirable titanium dust. Analysis of the titanium dioxide concentrations in the rat’s lungs showed that the lung clearance mechanism was overwhelmed and that the results at the massive 250 mg/m3 level are not relevant to the workplace.‘Results of a DuPont epidemiology study showed that employees who had been exposed to Titanium Dioxide were at no greater risk of developing lung cancer than were employees who had not been exposed to Titanium dioxide. No pulmonary fibrosis was found in any of the employees and no association was observed between Titanium dioxide exposure and chronic respiratory disease or x-ray abnormalities. Based on the results of this study DuPont concludes that titanium dioxide will not cause lung cancer or chronic respiratory disease in humans at concentrations experienced in the workplace.‘ Titanium dioxide (rutile) Is an IARC, NTP or OSHA carcinogen. In a lifetime inhalation test, lung cancers were found in some rats exposed to 250 mg/m3 respirable titanium dust. Analysis of the titanium dioxide concentrations in the rat’s lungs showed that the lung clearance mechanism was overwhelmed and that the results at the massive 250 mg/m3 level are not relevant to the workplace.‘Results of a DuPont epidemiology study showed that employees who had been exposed to Titanium Dioxide were at no greater risk of developing lung cancer than were employees who had not been exposed to Titanium dioxide. No pulmonary fibrosis was found in any of the employees and no association was observed between Titanium dioxide exposure and chronic respiratory disease or x-ray abnormalities. Based on the results of this study DuPont concludes that titanium dioxide will not cause lung cancer or chronic respiratory disease in humans at concentrations experienced in the workplace.‘ Toluene Increased susceptibility to the effects of this material may be observed in people with preexisting disease of any of the following: central nervous system, kidneys, liver, respiratory system, skin. Can be absorbed through the skin in harmful amounts. Recurrent overexposure may result in liver and kidney injury. High airborne levels have produced irregular heart beats in animals and occasional palpitations in humans. Rats exposed to very high airborne levels have exhibited high frequency hearing deficits. The significance of this to man is unknown. WARNING: This chemical is known to the State of California to cause birth defects or other reproductive harm. Xylene Increased susceptibility to the effects of this material may be observed in people with preexisting disease of any of the following: bone marrow, cardiovascular system, central nervous system, kidneys, liver, lungs. Recurrent overexposure may result in liver and kidney injury. High exposures may produce irregular heart beats. Canada classifies Xylene as a developmental toxin as high exposures to xylenes in some animal studies have been reported to cause health effects on the developing fetus/embryo. These effects were often at levels toxic to the adult animal. The significance of these effects to humans is not known. Repeated or prolonged skin contact may cause any of the following: irritation, dryness, cracking of the skin.