Note: Ingredients listed on restricted chemical lists
EC/CAS
52-24-4
Name of the chemical
Thiotepa (INN)
Concentration
<=100
General Information
Version
5
Revision date
2026-07-22
Product name
Tri(1-aziridinyl)phosphine sulfide
Product Synonyms
Thio-TEPA; Tris(1-aziridinyl)phosphine sulfide
CAS No.
52-24-4
supplier name
Avocado Research Chemicals Ltd
Emergency telephone
001-201-796-7100, +32 14 57 52 99, 001-800-424-9300, 001-703-527-3887
Icons in SDS
Company Information
company name
Avocado Research Chemicals Ltd
e-mail address of the competent person responsible for the Safety Data Sheet
begel.sdsdesk@thermofisher.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H300, H340, H350
Hazard statements
Code
Statements
H300
Fatal if swallowed
Section 2
SECTION 2: Hazards identification
Physical State
Appearance/Odor
Powder Solid White Slight Emergency Overview Fatal if swallowed. May cause genetic defects. May cause cancer. May form combustible dust concentrations in air. Classification of the substance or mixture Acute Oral Toxicity Category 2 Germ Cell Mutagenicity Category 1A Carcinogenicity Category 1A Label Elements
Signal word
Danger Hazard Statements H300 - Fatal if swallowed H340 - May cause genetic defects H350 - May cause cancer
Prevention
P201 - Obtain special instructions before use P202 - Do not handle until all safety precautions have been read and understood P264 - Wash face, hands and any exposed skin thoroughly after handling P270 - Do not eat, drink or smoke when using this product P280 - Wear protective gloves/protective clothing/eye protection/face protection
Response
P330 - Rinse mouth P301 + P310 - IF SWALLOWED: Immediately call a POISON CENTER or doctor P308 + P313 - IF exposed or concerned: Get medical advice/attention
Storage
P403 + P233 - Store in a well-ventilated place. Keep container tightly closed P405 - Store locked up
Disposal
P501 - Dispose of contents/ container to an approved waste disposal plant
Other physicochemical hazards
None identified. May form combustible dust concentrations in air.
Health hazards
Very toxic if swallowed. May cause genetic defects. May cause cancer.
Environmental hazards
Contains no substances known to be hazardous to the environment or not degradable in waste water treatment plants. Will likely be mobile in the environment due to its water solubility. The product is water soluble, and may spread in water systems. May form explosible dust-air mixture if dispersed. This product does not contain any known or suspected endocrine disruptors.
2.1 Classification of the substance or mixture
Acute Oral Toxicity Category 2 Germ Cell Mutagenicity Category 1A Carcinogenicity
