Note: Ingredients listed on restricted chemical lists
EC/CAS
372-31-6
Name of the chemical
Ethyl 4,4,4-trifluoroacetoacetate
Concentration
>95
General Information
Version
5
Revision date
2026-07-22
Product name
Ethyl trifluoroacetoacetate
Product Synonyms
Ethyl 3-oxo-4,4,4-trifluoroacetoacetate
CAS No.
372-31-6
supplier name
Avocado Research Chemicals Ltd
Emergency telephone
001-201-796-7100, +32 14 57 52 99, 001-800-424-9300, 001-703-527-3887
Icons in SDS
Company Information
company name
Avocado Research Chemicals Ltd
e-mail address of the competent person responsible for the Safety Data Sheet
begel.sdsdesk@thermofisher.com
GHS Information
Signal word
Warning
Hazard Codes
Hazard statements (CLP)
H226, H302, H412
Hazard statements
Code
Statements
H226
Flammable liquid and vapour
Section 2
SECTION 2: Hazards identification
Physical State
Appearance/Odor
Liquid Light yellow Odorless Emergency Overview Highly flammable liquid and vapor. Harmful if swallowed. Harmful to aquatic life with long lasting effects. Hygroscopic. Classification of the substance or mixture Flammable liquids Category 3 Acute Oral Toxicity Category 4 Chronic aquatic toxicity Category 3 Label Elements
Signal word
Warning Hazard Statements H226 - Flammable liquid and vapor H302 - Harmful if swallowed H412 - Harmful to aquatic life with long lasting effects
Prevention
P241 - Use explosion-proof electrical/ ventilating/ lighting equipment P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking P233 - Keep container tightly closed P240 - Ground and bond container and receiving equipment P243 - Take action to prevent static discharges P264 - Wash face, hands and any exposed skin thoroughly after handling P242 - Use non-sparking tools P270 - Do not eat, drink or smoke when using this product P280 - Wear protective gloves/protective clothing/eye protection/face protection
Response
P301 + P312 - IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower P330 - Rinse mouth P370 + P378 - In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish P374 - Fight fire with normal precautions from a reasonable distance P380 - Evacuate area
Storage
P403 + P235 - Store in a well-ventilated place. Keep cool
Disposal
P501 - Dispose of contents/ container to an approved waste disposal plant
Other physicochemical hazards
Highly flammable. Vapors may cause flash fire or explosion. Hygroscopic.
Health hazards
Harmful if swallowed.
Environmental hazards
Harmful to aquatic life with long lasting effects. Will likely be mobile in the environment due to its water solubility. The product is water soluble, and may spread in water systems. This product does not contain any known or suspected endocrine disruptors.
2.1 Classification of the substance or mixture
Flammable liquids. Category 3 Acute Oral Toxicity Category 4 Chronic aquatic toxicity
