beta-Propiolactone

Avocado Research Chemicals Ltd

Revision date : 2026-07-22

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GHS06 GHS08
Health risk rating 5
Safety risk rating 1
Environmental risk rating 1

Note: Ingredients listed on restricted chemical lists

General Information

Version

8

Revision date

2026-07-22

Product name

beta-Propiolactone

Product Synonyms

2-Oxetanone

CAS No.

57-57-8

supplier name

Avocado Research Chemicals Ltd

Emergency telephone

001-201-796-7100, +32 14 57 52 99, 001-800-424-9300, 001-703-527-3887

Icons in SDS

GHS06 GHS08 M004 M009 M010 M011 M013 M017

Company Information

company name

Avocado Research Chemicals Ltd

e-mail address of the competent person responsible for the Safety Data Sheet

begel.sdsdesk@thermofisher.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H227, H315, H319, H330, H350

Hazard statements

Code

Statements

H227

Combustible liquid

Section 2

SECTION 2: Hazards identification

Physical State

Appearance/Odor

Liquid Colorless pungent Emergency Overview Combustible liquid. Causes skin irritation. Causes serious eye irritation. Fatal if inhaled. May cause cancer. Moisture sensitive. Classification of the substance or mixture Flammable liquids Category 4 Acute Inhalation Toxicity - Vapors Category 2 Skin Corrosion/Irritation Category 2 Serious Eye Damage/Eye Irritation Category 2 Carcinogenicity Category 1B Label Elements

Signal word

Danger Hazard Statements H227 - Combustible liquid H315 - Causes skin irritation H319 - Causes serious eye irritation H330 - Fatal if inhaled H350 - May cause cancer

Prevention

P201 - Obtain special instructions before use P202 - Do not handle until all safety precautions have been read and understood P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking P260 - Do not breathe dust/fume/gas/mist/vapors/spray P264 - Wash face, hands and any exposed skin thoroughly after handling P271 - Use only outdoors or in a well-ventilated area P280 - Wear eye protection/ face protection P284 - Wear respiratory protection

Response

P370 + P378 - In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish P302 + P352 - IF ON SKIN: Wash with plenty of soap and water P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P310 - Immediately call a POISON CENTER or doctor P362 + P364 - Take off contaminated clothing and wash it before reuse

Storage

P403 + P233 - Store in a well-ventilated place. Keep container tightly closed P405 - Store locked up

Disposal

P501 - Dispose of contents/ container to an approved waste disposal plant

Other physicochemical hazards

Combustible material.

Health hazards

Causes skin irritation. Causes serious eye irritation. Fatal if inhaled. May cause cancer.

Environmental hazards

Contains no substances known to be hazardous to the environment or not degradable in waste water treatment plants. Will likely be mobile in the environment due to its water solubility. The product is water soluble, and may spread in water systems. Toxic to terrestrial vertebrates. This product does not contain any known or suspected endocrine disruptors.

2.1 Classification of the substance or mixture

Flammable liquids. Category 4 Acute Inhalation Toxicity - Vapors Category 2 Skin Corrosion/Irritation Category 2 Serious Eye Damage/Eye Irritation Category 2 Carcinogenicity

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