Note: Ingredients listed on restricted chemical lists
General Information
Version
8
Revision date
2026-07-25
Product name
1,1,1-Trifluoroacetone
Product Synonyms
1,1,1-Trifluoro-2-propanone
CAS No.
421-50-1
supplier name
Avocado Research Chemicals Ltd
Emergency telephone
001-201-796-7100, +32 14 57 52 99, 001-800-424-9300, 001-703-527-3887
Icons in SDS
Company Information
company name
Avocado Research Chemicals Ltd
e-mail address of the competent person responsible for the Safety Data Sheet
begel.sdsdesk@thermofisher.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H224, H314, H412
Hazard statements
Code
Statements
H224
Extremely flammable liquid and vapour
Section 2
SECTION 2: Hazards identification
Physical State
Appearance/Odor
Liquid Colorless Characteristic Emergency Overview Extremely flammable liquid and vapor. Causes severe skin burns and eye damage. Harmful to aquatic life with long lasting effects. Hygroscopic. Lachrymator (substance which increases the flow of tears). Classification of the substance or mixture Flammable liquids Category 1 Skin Corrosion/Irritation Category 1 B Serious Eye Damage/Eye Irritation Category 1 Chronic aquatic toxicity Category 3 Label Elements
Signal word
Danger Hazard Statements H224 - Extremely flammable liquid and vapor H314 - Causes severe skin burns and eye damage H412 - Harmful to aquatic life with long lasting effects
Prevention
P241 - Use explosion-proof electrical/ ventilating/ lighting equipment P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking P240 - Ground and bond container and receiving equipment P280 - Wear protective gloves/protective clothing/eye protection/face protection P242 - Use non-sparking tools P243 - Take action to prevent static discharges P264 - Wash face, hands and any exposed skin thoroughly after handling P271 - Use only outdoors or in a well-ventilated area
Response
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P310 - Immediately call a POISON CENTER or doctor P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing P370 + P378 - In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish P362 + P364 - Take off contaminated clothing and wash it before reuse
Storage
P403 + P233 - Store in a well-ventilated place. Keep container tightly closed
Disposal
P501 - Dispose of contents/ container to an approved waste disposal plant
Other physicochemical hazards
Vapors may cause flash fire or explosion. Extremely flammable. Hygroscopic.
Health hazards
Corrosive. Causes skin and eye burns.
Environmental hazards
Harmful to aquatic life with long lasting effects. Will likely be mobile in the environment due to its volatility. The product contains volatile organic compounds (VOC) which will evaporate easily from all surfaces.
2.3 Other hazards
Lachrymator (substance which increases the flow of tears) This product does not contain any known or suspected endocrine disruptors.
2.1 Classification of the substance or mixture
Flammable liquids. Category 1 Skin Corrosion/Irritation Category 1 B Serious Eye Damage/Eye Irritation Category 1 Chronic aquatic toxicity