DICHLOROMETHANE

SECTION 2: Hazards identification

OSHA Hazards Identification Emergency Emergency overview overview WARNING Possible cancer hazard - may cause cancer based on animal data. Harmful if inhaled or swallowed. Causes skin and eye irritation. High vapor concentrations may cause drowsiness and irritation of the eyes or respiratory tract. May cause an increase in carboxyhemoglobin levels. OSHA OSHA regulatory regulatory regulatory status status This product is considered hazardous under 29 CFR 1910.1200 (Hazard Communication).

Potential health effects

Potential health health effects Routes Routes of of of of exposure exposure Inhalation. Ingestion. Skin contact. Eye contact. Eyes Causes eye irritation. Skin Causes skin irritation. Inhalation Harmful if inhaled. May cause cancer by inhalation. High vapor concentrations may cause drowsiness. High vapor concentrations are irritating to the eyes, nose, throat, and lungs. Ingestion Harmful if swallowed. Irritating. May cause nausea, stomach pain and vomiting. Target Target organs organs Eyes. Skin. Central nervous system. Liver. Heart and cardiovascular system. Blood.

Potential chronic health

Chronic effects Possible cancer hazard - may cause cancer based on animal data. May cause an increase in carboxyhemoglobin levels. Frequent or prolonged contact may defat and dry the skin, leading to discomfort and dermatitis. Chronic effects May cause an increase in carboxyhemoglobin levels. Frequent or prolonged contact may defat and dry the skin, leading to discomfort and dermatitis. Carcinogenicity Possible cancer hazard - may cause cancer based on animal data. ACGIH ACGIH Carcinogens Carcinogens DICHLOROMETHANE (CAS 75-09-2) A3 Confirmed animal carcinogen with unknown relevance to humans. IARC IARC Monographs. Monographs. Monographs. Overall Overall Overall Evaluation Evaluation Evaluation of of of of Carcinogenicity Carcinogenicity DICHLOROMETHANE (CAS 75-09-2) 2B Possibly carcinogenic to humans. US US US US NTP NTP NTP Report Report Report on on on on Carcinogens: Carcinogens: Carcinogens: Anticipated Anticipated Anticipated carcinogen carcinogen DICHLOROMETHANE (CAS 75-09-2) Anticipated carcinogen. US US US US OSHA OSHA OSHA Specifically Specifically Specifically Regulated Regulated Regulated Substances: Substances: Substances: Potential Potential Potential cancer cancer cancer hazard DICHLOROMETHANE (CAS 75-09-2) Potential cancer hazard. Skin Skin corrosion/irritation corrosion/irritation Causes skin irritation. Epidemiology No epidemiological data is available for this product. Mutagenicity Not classified. Neurological Neurological effects effects High vapor/aerosol concentrations (attainable only at elevated temperatures) may cause central nervous system effects such as dizziness, drowsiness or headaches. Reproductive Reproductive effects effects Contains no ingredient listed as toxic to reproduction

Environmental effects

Potential environmental environmental effects The product components are not classified as environmentally hazardous. However, this does not exclude the possibility that large or frequent spills can have a harmful or damaging effect on the environment. 3333. . . . Composition Composition Composition / / / / Information Information Information on on on on Ingredients Ingredients Components CAS CAS # # # # Percent DICHLOROMETHANE 75-09-2 99 - 100 4444. . . . First First First Aid Aid Aid Measures Measures First First aid aid aid procedures procedures Eye Eye contact contact Immediately flush with plenty of water for at least 15 minutes. If easy to do, remove contact lenses. Get medical attention. Skin Skin contact contact In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash contaminated clothing before reuse. Destroy or thoroughly clean contaminated shoes. Inhalation Move to fresh air. If breathing is difficult, give oxygen. If breathing stops, provide artificial respiration. Get medical attention immediately. Ingestion Call a physician or poison control center immediately. Only induce vomiting at the instruction of medical personnel. Never give anything by mouth to an unconscious person. If vomiting occurs, keep head low so that stomach content doesn't get into the lungs. Notes Notes to to to to physician physician Excessive carboxyhemoglobin from acute Carbon Monoxide poisoning is best reversed by aggressive oxygen therapy within the limits of oxygen toxicity. Hyperbaric treatment, if available, is especially useful in severe cases. Consult a poison control center for guidance. Treat symptomatically. Symptoms may be delayed. General General advice advice Ensure that medical personnel are aware of the material(s) involved, and take precautions to protect themselves. Show this safety data sheet to the doctor in attendance. 5555. . . . Fire Fire Fire Fighting Fighting Fighting Measures Measures Flammable Flammable properties properties This product is not flammable. May burn, but does not ignite readily. Extinguishing Extinguishing media media Suitable Suitable extinguishing extinguishing Water. Carbon dioxide (CO2). Dry chemical powder. Foam. media Unsuitable Unsuitable extinguishing extinguishing None known. media Protection Protection of of of of firefighters firefighters Specific Specific hazards hazards arising arising Fire may produce irritating, corrosive and/or toxic gases. from from the the the chemical chemical Protective Protective equipment equipment equipment and and Use water spray to cool unopened containers. Self-contained breathing apparatus and full Environmental effects Ecological injuries are not known or expected under normal use. An environmental hazard cannot be excluded in the event of unprofessional handling or disposal. Persistence Persistence and and Expected to biodegrade slowly. degradability Partition Partition coefficient coefficient 1.25 (n-octanol/water) 13 13. 13 13 . . . Disposal

Precautionary statements

precautions for for for firefighters firefighters protective clothing must be worn in case of fire. Cool containers exposed to flames with water until well after the fire is out. Special Special protective protective protective equipment equipment equipment for for Wear full protective clothing, including helmet, self-contained positive pressure or pressure fire-fighters demand breathing apparatus, protective clothing and face mask. Wear self-contained breathing apparatus with a full facepiece operated in the positive pressure demand mode when fighting fires. Specific Specific methods methods In the event of fire and/or explosion do not breathe fumes. Hazardous Hazardous combustion combustion combustion products products Carbon monoxide and carbon dioxide. Hydrogen Chloride (HCl). 6666. . . . Accidental Accidental Accidental Release Release Release Measures Measures Personal Personal precautions Wear appropriate protective equipment and clothing during clean-up. Keep upwind. Keep out of low areas. Ventilate closed spaces before entering them. Local authorities should be advised if significant spillages cannot be contained. Environmental Environmental precautions Prevent further leakage or spillage if safe to do so. Avoid discharge into drains, water courses or onto the ground. Methods Methods for for for containment containment Stop the flow of material, if this is without risk. Dike the spilled material, where this is possible. Prevent entry into waterways, sewer, basements or confined areas. Methods Methods for for for cleaning cleaning cleaning up up up up Large Spills: Dike far ahead of spill for later disposal. Use a non-combustible material like vermiculite, sand or earth to soak up the product and place into a container for later disposal. Small Spills: Wipe up with absorbent material (e.g. cloth, fleece). Clean surface thoroughly to remove residual contamination. Never return spills in original containers for re-use. Clean up in accordance with all applicable regulations. Collect in a non-combustible container for prompt disposal. 7777. . . . Handling Handling Handling and and and Storage

Storage

Handling Wear appropriate personal protective equipment. Avoid breathing mist or vapor. Avoid contact with eyes, skin, and clothing. Do not taste or swallow. Wash thoroughly after handling. See Section 8 of the MSDS for Personal Protective Equipment. Keep tightly closed in a dry, cool and well-ventilated place. 8888. . . . Exposure Exposure Exposure Controls Controls Controls / / / / Personal Personal Personal Protection Protection ACGIH Material Type Value DICHLOROMETHANE (75-09-2) BEL 0.3000 mg/l TWA 50.0000 ppm Occupational Occupational exposure exposure exposure limits limits UUUU....SSSS. . . . - - - - OSHA OSHA Material Type Value DICHLOROMETHANE (75-09-2) STEL 125.0000 ppm TWA 25.0000 ppm Engineering Engineering controls controls Good general ventilation (typically 10 air changes per hour) should be used. Ventilation rates should be matched to conditions. If applicable, use process enclosures, local exhaust ventilation, or other engineering controls to maintain airborne levels below recommended exposure limits. If exposure limits have not been established, maintain airborne levels to an acceptable level. Personal Personal protective protective protective equipment equipment Eye Eye / / / / face face face protection protection Wear safety glasses with side shields (or goggles) and a face shield. Skin Skin protection protection Wear appropriate chemical resistant clothing. Wear appropriate chemical resistant gloves. Respiratory Respiratory protection protection Use a positive-pressure air-supplied respirator if there is any potential for an uncontrolled release, exposure levels are not known, or any other circumstances where air-purifying respirators may not provide adequate protection. General General hygeine hygeine Provide eyewash station and safety shower. Always observe good personal hygiene measures, considerations such as washing after handling the material and before eating, drinking, and/or smoking. Routinely wash work clothing and protective equipment to remove contaminants. General Wear chemical protective equipment that is specifically recommended by the manufacturer. Launder contaminated clothing before reuse. 9999. . . . Physical Physical Physical & & & & Chemical Chemical Chemical Properties Properties Appearance Clear. Color Colorless. Odor Sweet. Pleasant. Odor Odor threshold threshold Not available. Physical Physical state state Liquid. Form Liquid. pH pH pH pH Not available. Melting Melting point point -139 °F (-95 °C) Freezing Freezing point point -139 °F (-95 °C) Boiling Boiling point point 104 °F (39.75 °C) 101.325 kPa Flash Flash point point Not available. Evaporation Evaporation rate rate 27.5 BuAc Flammability Flammability limits limits limits in in in in air, air, air, upper, upper, 66.4 % % % % % by by by by volume volume Flammability Flammability limits limits limits in in in in air, air, air, lower, lower, 15.5 % % % % % by by by by volume volume Vapor Vapor pressure pressure 58 kPa at 25°C Vapor Vapor density density 2.93 Specific Specific gravity gravity 1.3255 Relative Relative density density Not available. Solubility Solubility (water) (water) 20 g/l Partition Partition coefficient coefficient 1.25 (n-octanol/water) Auto-ignition Auto-ignition temperature temperature 1033 °F (556.1 °C) Molecular Molecular weight weight 84.93 g/mol Molecular Molecular formula formula C-H2-Cl2 10 10. 10 10 . . . Chemical Chemical Chemical Stability Stability Stability & & & & Reactivity Reactivity Reactivity Information Information Chemical Chemical stability stability Material is stable under normal conditions. Conditions Conditions to to to to avoid avoid Excessive heat. Moisture. Incompatible Incompatible materials materials Strong oxidizing agents. Acids. Caustics. Aluminum. Chemically active metals. May attack some plastics, rubber and coatings. Hazardous Hazardous decomposition decomposition Carbon oxides. Hydrogen chloride. Phosgene. products Possibility Possibility of of of of hazardous hazardous Hazardous polymerization does not occur. reactions 11 11 11 11. . . . Toxicological

TOXICOLOGICAL INFORMATION

Toxicological Information Toxicological Toxicological data data Product Test Test Results Results DICHLOROMETHANE (75-09-2) Acute Inhalation LC50 Rat: 76 mg/l 4.00 Hours Acute Oral LD50 Rat: 1600 mg/kg Sensitization Not a skin sensitizer. Acute Acute effects effects Harmful if inhaled or swallowed. May cause an increase in carboxyhemoglobin levels. Local Local effects effects Causes skin and eye irritation. High vapor concentrations may cause drowsiness and irritation of the eyes or respiratory tract.

Teratogenic Effects

Components in this product have been shown to cause birth defects and reproductive disorders in laboratory animals. The relevance to humans is uncertain. Symptoms Symptoms and and and target target Irritant effects. Drowsiness and dizziness. Decrease in motor functions. Shortness of breath. organs Unconsciousness. 12 12. 12 12 . . . Ecological

ECOLOGICAL INFORMATION

Ecological Information Ecotoxicological Ecotoxicological data data Product Test Test Results Results DICHLOROMETHANE (75-09-2) EC50 Water flea (Daphnia magna): 1250 mg/l 48.00 hours LC50 Fathead minnow (Pimephales promelas): 140.8 mg/l 96.00 hours Ecotoxicity Not expected to be harmful to aquatic organisms.

Disposal

Considerations Considerations Waste Waste codes codes US US US US RCRA RCRA RCRA Hazardous Hazardous Hazardous Waste Waste Waste U U U U List: List: List: Reference Reference DICHLOROMETHANE (CAS 75-09-2) U080 Disposal instructions instructions Dispose of this material and its container to hazardous or special waste collection point. Incinerate the material under controlled conditions in an approved incinerator. All wastes must be handled in accordance with local, state and federal regulations. Contaminated Contaminated packaging packaging Offer rinsed packaging material to local recycling facilities. Since emptied containers retain product residue, follow label warnings even after container is emptied. 14 14. 14 14 . . . Transport Transport Transport Information Information DOT Basic Basic shipping shipping shipping requirements: requirements: UN UN UN UN number number UN1593 Proper Proper shipping shipping shipping name name Dichloromethane

Hazard categories

Hazard class 6.1 Packing Packing group group III Hazard class 6.1 Packing Packing group group III Hazard class 6.1 Packing Packing group group III DOT IATA IMDG 15 15. 15 15 . . . Regulatory Regulatory Regulatory Information Information US US US US federal federal federal regulations regulations This product is a "Hazardous Chemical" as defined by the OSHA Hazard Communication Standard, 29 CFR 1910.1200. All components are on the U.S. EPA TSCA Inventory List. See OSHA Standard for medical surveillance, record keeping, and reporting requirements for methylene chloride (29 CFR 1910.1052). US US US US EPCRA EPCRA EPCRA (SARA (SARA (SARA Title Title Title III) III) III) Section Section 313 313 - - - - Toxic Toxic Toxic Chemical: Chemical: Chemical: De De De De minimis minimis minimis concentration concentration DICHLOROMETHANE (CAS 75-09-2) 0.1 % US US US US EPCRA EPCRA EPCRA (SARA (SARA (SARA Title Title Title III) III) III) Section Section 313 313 - - - - Toxic Toxic Toxic Chemical: Chemical: Chemical: Listed Listed Listed substance

Additional information

Additional information: Additional information: Packaging Packaging exceptions exceptions 153 Packaging Packaging non non non bulk bulk 203 Packaging Packaging bulk bulk 241 Reportable Reportable quantity quantity 1000 ERG ERG number number 160 IATA Basic Basic shipping shipping shipping requirements: requirements: UN UN UN Additional information: ERG ERG code code 6L IMDG Basic Basic shipping shipping shipping requirements: requirements: UN UN UN UN number number 1593 Proper Proper shipping shipping shipping name name DICHLOROMETHANE

Special Provisions

Special provisions IB3, IP8, N36, T7, TP2 Basic Basic shipping shipping shipping requirements: requirements: Labels Labels required required 6.1

UN Number

number 1593 Proper Proper shipping shipping shipping name name Dichloromethane