Note: Ingredients listed on restricted chemical lists
EC/CAS
7727-37-9
Name of the chemical
Nitrogen N2
Concentration
N/A
General Information
Revision date
2021-11-24
Product name
Cyclophosphamide Injection
Chemical name
2-[bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2- oxazaphosphorine 2-oxide monohydrate
Emergency telephone
855-273-0154
Icons in SDS
Company Information
company name
Athenex Pharmaceutical Division
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H302, H315, H317, H318, H340, H350, H360, H362, H372
Hazard statements
Code
Statements
H302
Harmful if swallowed
Section 2
2.1 Classification of the substance or mixture
Acute Oral Toxicity Category 4 substance or mixture: Skin Corrosion/Irritation Category 2 Serious Eye Damage/Eye Category 1 Irritation Skin Sensitization Category 1 Germ Cell Mutagenicity Category 1A Carcinogenicity Category 1A Reproductive Toxicity Category 1A Effects on or via lactation Effects on or via Lactation Specific Target Organ Category 1 Toxicity (Repeated Exposure) Ozone Not Applicable (b) Signal Word, Hazard statement(s), Symbol(s), and/or Precautionary statement(s):
Signal word
Warning
Hazard statements
H302 - Harmful if swallowed H315 - Causes skin irritation H317 - May cause an allergic skin reaction H318 - Causes serious eye damage H340 - May cause genetic defects H350 - May cause cancer H360 - May damage fertility or the unborn child H362 - May cause harm to breast-fed children H372 - Causes damage to organs through prolonged or repeated exposure CENTRE or doctor/physician P332 + P313 - If skin irritation occurs: Get medical advice/attention P362 - Take off contaminated clothing and wash before reuse P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P310 - Immediately call a POISON CENTRE or doctor/physician P261 - Avoid breathing dust/fume/gas/mist/vapors/spray P272 - Contaminated work clothing should not be allowed out of the workplace P280 - Wear protective gloves/protective clothing/eye protection/ face protection P302+ P352 - IF ON SKIN: Wash with plenty of soap and water P333 + P313 - If skin irritation or rash occurs: Get medical advice/attention P321 - Specific treatment (see supplemental first aid instructions on this label) P363 - Wash contaminated clothing before reuse P263 - Avoid contact during pregnancy/while nursing P260 - Do not breathe dust/fume/gas/mist/vapors/spray P314 - Get medical attention/advice if you feel unwell P201 - Obtain special instructions before use P202 - Do not handle until all safety precautions have been read and understood P281 - Use personal protective equipment as required P308 + P313 - IF exposed or concerned: Get medical attention/advice P405 - Store locked up P264 - Wash face, hands and any exposed skin thoroughly after handling P270 - Do not eat, drink or smoke when using this product P301+ P312 - IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell P330 - Rinse mouth P501 - Dispose of contents/container to an approved waste disposal plant
Precautionary statements
P301+ P310 - IF SWALLOWED: Immediately call a POISON
Potential Acute Health Effects
May cause eye, skin and respiratory tract irritation. Individuals sensitive to this chemical or other materials in its chemical class may develop allergic reactions. This compound can cross the placenta in pregnant women. Secreted in human breast milk. Adverse effects: The most common adverse effects reported with clinical use were diarrhea, nausea, rash, and vomiting. Effects on blood and blood-forming organs have also occurred. (d) Unknown Acute Toxicity N/A