PEP SET™ Q II 6180 BINDER

SECTION 2: Hazards identification

Emergency Overview Appearance: liquid, brown WARNING! COMBUSTIBLE LIQUID AND VAPOR. MAY AFFECT THE CENTRAL NERVOUS SYSTEM CAUSING DIZZINESS, HEADACHE OR NAUSEA. MAY BE HARMFUL IF INHALED. MAY CAUSE ALLERGIC RESPIRATORY REACTION. MAY CAUSE EYE IRRITATION. MAY CAUSE ALLERGIC SKIN REACTION. MAY CAUSE SKIN AND RESPIRATORY TRACT IRRITATION. PROLONGED OR REPEATED CONTACT MAY DRY SKIN AND CAUSE DERMATITIS AND BURNS.

Principle Routes of Exposure

Inhalation, Skin absorption, Skin contact, Eye Contact, Ingestion Eye contact Can cause eye irritation. Symptoms include stinging, tearing, redness, and swelling of eyes. Skin contact Can cause skin irritation. Symptoms may include redness and burning of skin, and other skin damage. May cause allergic skin reaction. Prolonged or repeated contact may dry the skin. Symptoms may include redness, burning, and drying and cracking of skin, skin burns, and other skin damage. Ingestion Swallowing small amounts of this material during normal handling is not likely to cause harmful effects. Swallowing large amounts may be harmful. This material can get into the lungs during swallowing or vomiting. This results in lung inflammation and other lung injury. Inhalation It is possible to breathe this material under certain conditions of handling and use (for example, during heating, spraying, or stirring). Breathing this material may be harmful. Symptoms are not expected at air concentrations below the recommended exposure limits, if applicable (see Section 8.). May cause allergic respiratory reaction. This product is a two-part urethane system. While breathing 4,4'-diphenylmethane diisocyanate (MDI) can be harmful or fatal, breathing MDI is not expected during normal use of this system.

Medical Conditions Generally Aggravated by Exposure

Preexisting disorders of the following organs (or organ systems) may be aggravated by exposure to this material:, Skin, Upper respiratory tract, lung (for example, asthma-like conditions), Kidney, immune system, eye, Exposure to this material may aggravate any preexisting condition sensitive to a decrease in available oxygen, such as chronic lung disease, coronary artery disease or anemias., Individuals with erythrocyte glucose-6-phosphate dehydrogenase deficiency are particularly susceptible to hemolytic agents and rapidly develop hemolytic anemia from ingestion or inhalation of this material (or a component). Symptoms Signs and symptoms of exposure to this material through breathing, swallowing, and/or passage of the material through the skin may include:, sweating, Fever, stomach or intestinal upset (nausea, vomiting, diarrhea), irritation (nose, throat, airways), Cough, Lung irritation, central nervous system depression (dizziness, drowsiness, weakness, fatigue, nausea, headache, unconsciousness), Abdominal pain, chest pain, confusion, Difficulty in breathing, blood abnormalities (breakage of red blood cells), lung edema (fluid buildup in the lung tissue), kidney damage, lung damage, respiratory failure, Exposure to this product (or a component) may cause an allergic reaction (narrowing of the air passages of the lungs resulting in difficult breathing, tightness in the chest, coughing and wheezing) in some sensitive individuals. Other symptoms of an allergic reaction may include itchy and watery eyes, runny and stuffy nose, sweating, flushing, hives, rapid heart rate, and lowered blood pressure. Target Organs This material (or a component) has been shown to lower activity of certain immune system cells in experimental animals. The significance of this effect with respect to human health is uncertain., Overexposure to this material (or its components) has been suggested as a cause of the following effects in laboratory animals:, mild, reversible liver effects, cataracts, anemia, eye damage, central nervous system damage, nasal damage, lung damage, Overexposure to this material (or its components) has been suggested as a cause of the following effects in humans:, effects on lung function, cataracts, eye damage Carcinogenicity In a two-year inhalation study in rats, exposure to polymeric methylene bisphenylisocyanate (MDI) aerosol caused a significant increase in benign (noncarcinogenic) lung tumors, along with a single carcinogenic lung tumor, at the highest dose only (6 mg/m3). The tumors occurred along with irritation of the respiratory tract and the accumulation of a yellow material in the lungs. There was irritation only at 1.0 mg/m3 and no effect at 0.2 mg/m3. MDI is not listed as carcinogenic by the International Agency for Research on Cancer (IARC), the National Toxicology Program (NTP) or the Occupational Safety and Health Administration (OSHA). In a National Toxicology Program (NTP) study, lifetime inhalation exposure to naphthalene resulted in increases in tumors of the nose in rats. In a previous NTP study, lifetime exposure to naphthalene caused lung tumors in female mice. Male mice with the same exposure did not develop tumors. The relevance of this finding to humans is uncertain. Naphthalene is listed as carcinogenic by IARC (International Agency for Research on Cancer) and the National Toxicology Program (NTP). Reproductive hazard This material (or a component) causes harm to the fetus.