STYRENE MONOMER 100 PPM INHIBITOR

Potential health effects

Eye Can cause eye irritation. Symptoms include stinging, tearing, redness, and swelling of eyes. Skin Can cause skin irritation. Prolonged or repeated contact may dry the skin. Symptoms may include redness, burning, and drying and cracking of skin, burns and other skin damage. Passage of this material into the body through the skin is possible, but it is unlikely that this would result in harmful effects during safe handling and use. Swallowing Swallowing small amounts of this material during normal handling is not likely to cause harmful effects. Swallowing large amounts may be harmful. This material can get into the lungs during swallowing or vomiting. This results in lung inflammation and other lung injury. Inhalation Breathing of vapor or mist is possible. Breathing small amounts of this material during normal handling is not likely to cause harmful effects. Breathing large amounts may be harmful. Symptoms usually occur at air concentrations higher than the recommended exposure limits (See Section 8). Symptoms of Exposure Signs and symptoms of exposure to this material through breathing, swallowing, and/or passage of the material through the skin may include: metallic taste, stomach or intestinal upset (nausea, vomiting, diarrhea), irritation (nose, throat, airways), central nervous system depression (dizziness, drowsiness, weakness, fatigue, nausea, headache, unconsciousness) and other central nervous system effects, loss of coordination, confusion, liver damage. Target Organ Effects Overexposure to this material (or its components) has been suggested as a cause of the following effects in laboratory animals: mild, reversible kidney effects, effects on hearing, respiratory tract damage (nose, throat, and airways), testis damage, liver damage, Overexposure to this material (or its components) has been suggested as a cause of the following effects in humans: mild effects on color vision, effects on hearing, respiratory tract damage (nose, throat, and airways), central nervous system effects. Developmental Information This material (or a component) has been shown to cause harm to the fetus in laboratory animal studies. Harm to the fetus occurs only at exposure levels that harm the pregnant animal. The relevance of these findings to humans is uncertain.

Cancer information

In 1993, the International Agency for Research on Cancer (IARC) classified styrene in group 2B (possibly carcinogenic to humans). IARC concluded that there was no convincing evidence for carcinogenic action of styrene in animals based on the animal studies which existed at that time. Rather, the IARC 2B listing was based on data for styrene oxide, a metabolite of styrene. Two recent lifetime studies with styrene, one in rats and one in mice, have been completed since the 1993 review. There was no increase in cancer in styrene-exposed rats. However, there was an increase in lung cancer in styrene-exposed mice. The relevance of the mouse lung cancer to humans is uncertain. Styrene exposure has not been associated with an increased incidence of cancer in workers including those in the reinforced plastics and composites plastics industries.

Other Health Effects

No data

Principle Routes of Exposure

Inhalation, Skin absorption, Skin contact, Eye contact, Ingestion.