Acetylcysteine Solution, USP

Hazard statements (CLP)

H315, H319, H335, H402

Code

Statements

H315

Causes skin irritation

SECTION 2: Hazards identification

Classification (GHS-US) Classification of the Substance or Mixture Classification (GHS-US) skin Irrit. 2 H315 Eye Irrit. 2A H319 STOTSE 3 H335 Aquatic Acute 3 H402 Full text of H-phrases: see section 16

2.2 Label elements

GHS-US Labeling

Signal word

Warning

Hazard statements

H315 - Causes skin irritation. H319 - Causes serious eye irritation. H335 - May cause respiratory irritation. H402 - Harmful to aquatic life.

Precautionary statements

P261- Avoid breathing vapors, mist, or spray. P264 - Wash hands, forearms, and other exposed areas thoroughly after handling. P271 - Use only outdoors or in a well-ventilated area. P273 - Avoid release to the environment. P280 - Wear protective gloves, protective clothing, and eye protection. P302+P352 - If on skin: Wash with plenty of water. P304+P340 - If inhaled: Remove person to fresh air and keep at rest in a position comfortable for breathing. P305+P351+P338 - If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312 - Call a poison center or doctor if you feel unwell. P321 - Specific treatment (see section 4 on this SDS). P332+P313 - If skin irritation occurs: Get medical advice/attention. P337+P313 - If eye irritation persists: Get medical advice/attention. P362 - Take off contaminated clothing and wash it before reuse. P403+P233 - Store in a well-ventilated place. Keep container tightly closed. P405 - Store locked up. P501 - Dispose of contents/container in accordance with local, regional, national, 01/09/2019 EN (English US) and international regulations. 2.3. Other Hazards May cause an allergic reaction in sensitive individuals. Some hypersensitivity reactions have been seen when this drug has been used. Photosensitivity allergic reaction has been reported by people with high blood pressure, high blood cholesterol, multiple sclerosis, depression, crohn's disease. 2.4. Unknown Acute Toxicity (GHS-US) No data available 3.1. Substance Not applicable 3.2. Mixture Name Product Identifier % Classification (GHS-US) Water (CAS No) 7732-18-5 75-875 Not classified L-Cysteine, N-acetyl- (CAS No) 616-91-1 10-20 Skin Irrit. 2, H315 Eye Irrit. 2A, H319 STOT SE 3, H335 Sodium hydroxide (CAS No) 1310-73-2 25-5 Met. Corr. 1, H290 skin Corr. 1A, H314 Eye Dam. 1, H318 Aquatic Acute 3, H402 Glycine, N,N'-1,2-ethanediylbis[N- (CAS No) 6381-92-6 0.03 Acute Tox. 4 (Oral), H302 (carboxymethyl)-, disodium salt, dihydrate Acute Tox. 4 (Dermal), H312 Acute Tox. 4 (Inhalation: dust, mist), H332 skin Irrit. 2, H315 Eye Irrit. 2A, H319 STOT SE 3, H335 Aquatic Chronic 3, H412 Hydrochloric acid (CAS No) 7647-01-0 * Met. Corr. 1, H290 Acute Tox. 3 (Inhalation:gas), H331 skin Corr. 1C, H314 Eye Dam. 1, H318 STOT SE 3, H335 Aquatic Acute 1, H400 *Added for pH adjustment Full text of H-phrases: see section 16 4.1. Description of First Aid Measures First-aid Measures General: Never give anything by mouth to an unconscious person. If you feel unwell, seek medical advice (show the label where possible). In the event of accidental injection, immediately call a poison center or seek medical advice. First-aid Measures After Inhalation When symptoms occur go into open air and ventilate suspected area. Seek medical attention. First-aid Measures After Skin Contact: Remove contaminated clothing. Flush with copious quantities of water for 15 minutes. Seek medical attention. First-aid Measures After Eye Contact: Immediately flush eyes thoroughly with water for at least 15 minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Seek medical attention. First-aid Measures After Ingestion: Rinse mouth. Do NOT induce vomiting. 4.2. Most important symptoms and effects, both acute and delayed Symptoms/Injuries: Please refer to the package insert for more detailed information. Symptoms/Injuries After Inhalation: May cause respiratory irritation. Symptoms/Injuries After Skin Contact: May cause skin irritation. Symptoms/Injuries After Eye Contact: May cause eye irritation. Symptoms/Injuries After Ingestion: Ingestion is likely to be harmful or have adverse effects. 4.3. Indication of Any Immediate Medical Attention and Special Treatment Needed Ifyou feel unwell, seek medical advice (show the label where possible). 01/09/2013 EN (English Us) 277 SECTION 5: FIRE-FIGHTING MEASURES 5.1. Extinguishing Media Suitable Extinguishing Media Water spray, carbon dioxide, foam, dry chemical. Caution CO2 will displace air in confined spaces and may cause an oxygen deficient atmosphere. Unsuitable Extinguishing Media: None known. 5.2. Special Hazards Al g From the Substance or Mixture Reactivity: May react with strong oxidizers, increasing risk of fire or explosion. 5.3. Advice for Firefighters Fi ing Instructions: Exercise caution when fighting any chemical fire. Use water spray or fog for cooling exposed containers. Protection During Firefighting: Firefighters must use full bunker gear including NIOSH-approved positive-pressure self-contained breathing apparatus to protect against potential hazardous combustion and decomposition products. SECTION 6: ACCIDENTAL RELEASE MEASURES 6.1. Personal Precautions, Protective Equipment and Emergency Procedures General Measures: Avoid all unnecessary exposure. Do not breathe vapour or mist. 6.1.1. For Non-emergency Personnel Protective Equipment: Use appropriate personal protection equipment (PPE). Refer to section 8.2. Emergency Procedures: Evacuate unnecessary personnel. 6.1.2. For Emergency Responders Protective Equipment Equip cleanup crew with proper protection. For further information refer to section 8 "Exposure controls/personal protection”. Emergency Procedures: Upon arrival at the scene, a first responder is expected to recognize the presence of dangerous goods, protect oneself and the public, secure the area, and call for the assistance of trained personnel as soon as conditions permit. 6.2. Environmental Precautions Prevent entry to sewers and public waters. 6.3. Methods and Material for Containment and Cleaning Up Methods for Cleaning Up: Vacuum spillage with a vacuum cleaner having a high efficiency particulate (HEPA) filter, or absorb liquid with clay absorbent, absorbent pads or paper towels. Use plastic tools to scoop up, sweep or containerize spilled material. Use plastic drums to contain spilled materials. Wipe working surfaces to dryness, and then wash with soap and water. 6.4. Reference to Other Sections See Section 8, Exposure Controls and Personal Protection. See Section 13, Disposal Considerations. CTION 7: HANDLING AND STORAGE 7.1. Precautions for Safe Handling

2.1 Classification of the substance or mixture

Classification (GHS-US) skin Irrit. 2 H315 Eye Irrit. 2A H319 STOTSE 3 H335 Aquatic Acute 3 H402 Full text of H-phrases: see section 16