Note: Ingredients listed on restricted chemical lists
EC/CAS
14807-96-6
Name of the chemical
Talc
Concentration
N/A
EC/CAS
238-877-9
Name of the chemical
Talc: Hydrated magnesium silicate
Concentration
N/A
General Information
Revision date
2018-09-29
Product name
Linzess
Product Synonyms
Linaclotide
1.2.1 Relevant identified uses
LINZESS is a guanylate cyclase-C agonist indicated in adults for treatment of:• Irritable
Manufacturer Name
Allergan plc
Emergency telephone
Call CHEMTREC Day or Night
Icons in SDS
Company Information
company name
Allergan plc
e-mail address of the competent person responsible for the Safety Data Sheet
SDS@Allergan.com
GHS Information
Signal word
Warning
Hazard Codes
Hazard statements (CLP)
H302, H319, H373
Hazard statements
Code
Statements
H302
Harmful if swallowed
Section 2
2.1 Classification of the substance or mixture
OSHA Regulatory Status This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) Acute toxicity - Oral Category 4 Serious eye damage/eye irritation Category 2 Specific target organ toxicity (repeated exposure) Category 2
2.2 Label elements
Emergency Overview Warning
Hazard statements
H302 - Harmful if swallowed H319 - Causes serious eye irritation H373 - May cause damage to organs through prolonged or repeated exposure Appearance Capsule Physical state Solid Odor No information available Chemical Name Symptoms Linaclotide The most commonly reported adverse reaction is diarrhea. Chemical Name
Medical Conditions Generally Aggravated by Exposure
Linaclotide This medication is contraindicated in children younger than 6 years old, and avoided in age groups 6-17 years old.
Precautionary statements
P270 - Do not eat, drink or smoke when using this product P301 + P312 - IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell P330 - Rinse mouth P264 - Wash face, hands and any exposed skin thoroughly after handling P280 - Wear protective gloves/protective clothing/eye protection/face protection P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P337 + P313 - If eye irritation persists: Get medical advice/attention P260 - Do not breathe dust/fume/gas/mist/vapors/spray P314 - Get medical advice/attention if you feel unwell P501 - Dispose of contents/ container to an approved waste disposal plant
Further information
Unknown Acute Toxicity 10% of the mixture consists of ingredient(s) of unknown toxicity Over the counter drugs in their solid form are considered exempt under the criteria of the Federal OSHA Hazard Communication Standard 20 CFR 1910.1200. However, in an industrial setting where a component's occupational exposure limit may be surpassed, than can be considered hazardous
