AMP Broadman Mn 20

Potential chronic health

High levels of manganese in the blood may increase anemia by interfering with iron absorption. Iron deficiency may increase an individula's susecptibility to manganese. Studies suggest that populations at risk of adverse effects due to manganese exposure are infants and those with existing iron deficiency. Disorders are reversible if recognized early and overexposure is eliminated. Inhalation of large quantities of manganese containing dusts over many years may result in damage to the central nervous system, with symptoms of sleepiness, tremors and weakness in the legs, slurred speech, emotional disturbances, loss of balance, and in more advanced cases, an irreversible condition with symptoms similar to Parkinsons or Lou Gehrig's disease including a mask-like facial expression, spastic gait, tremors, slurred speech, fatigue, anorexia, apathy, and inability to concentrate in more advanced cases. The neurologic disorder that develops is known as "manganism". A syndrome may develop with symptoms of compulsive behavior, emotional volatility and hallucinations. Carcinogenicity No known significant effects or critical hazards. Mutagenicity No known significant effects or critical hazards.

Teratogenic Effects

No known significant effects or critical hazards. Developmental effects No known significant effects or critical hazards. Fertility effects No known significant effects or critical hazards. Target organs Contains material which may cause damage to the following organs: blood, kidneys, liver, digestive system, gastrointestinal tract, cardiovascular system, upper respiratory tract, skin, adrenal, central nervous system (CNS), nose/sinuses, pancreas, testes, throat. Contains material which does not cause damage to the following organs: eye, lens or cornea. Over-exposure signs/symptoms Inhalation No specific data. Ingestion No specific data. Skin Adverse symptoms may include the following: irritation redness Eyes Adverse symptoms may include the following: pain or irritation watering redness Medical conditions Pre-existing disorders involving any target organs mentioned in this MSDS as being aggravated by over- at risk may be aggravated by over-exposure to this product. exposure See toxicological information (Section 11) 3 .