Absolutely RNA FFPE Kit, Part Number 400809 400809

Hazard statements (CLP)

H226, H301, H301+H331, H302, H302+H332, H310, H315, H317, H318, H331, H332, H361f, H373, H400, H410, H411, H412

Code

Statements

H226

Flammable liquid and vapour

H301

Toxic if swallowed

H301+H331

Toxic if swallowed or if inhaled

H302

Harmful if swallowed

H302+H332

Harmful if swallowed or if inhaled

H310

Fatal in contact with skin

H315

Causes skin irritation

H317

May cause an allergic skin reaction

H318

Causes serious eye damage.

H331

Toxic if inhaled

H332

Harmful if inhaled

H361f

Suspected of damaging fertility.

H373

May cause damage to organs through prolonged or repeated exposure

H400

Very toxic to aquatic life

H410

Very toxic to aquatic life with long lasting effects

H411

Toxic to aquatic life with long lasting effects

H412

Harmful to aquatic life with long lasting effects

SECTION 2: Hazards identification

Classification according to Regulation (EC) No. 1272/2008 [CLP/GHS]]

Product definition

RNase-Free DNase I UVCB (Lyophilized) ß-Mercaptoethanol Mono-constituent substance De-paraffinization Mono-constituent substance Reagent d-limonene RNA Binding Buffer Mixture 1.67X High Salt Wash Mixture Buffer 5x Low Salt Wash Buffer Mixture Elution Buffer Mixture DNase Reconstitution Mixture Buffer DNase Digestion Buffer Mixture Proteinase K Mixture Proteinase K Digestion Mixture Buffer QPCR Human Mixture Reference Total RNA

Hazard pictograms

ß-Mercaptoethanol De-paraffinization Reagent d-limonene RNA Binding Buffer 1.67X High Salt Wash Buffer DNase Digestion Buffer

Signal word

RNase-Free DNase I No signal word. (Lyophilized) ß-Mercaptoethanol Danger De-paraffinization Warning Reagent d-limonene RNA Binding Buffer Warning 1.67X High Salt Wash Warning Buffer 5x Low Salt Wash Buffer No signal word. Elution Buffer No signal word. DNase Reconstitution No signal word. Buffer DNase Digestion Buffer Warning Proteinase K No signal word. Proteinase K Digestion No signal word. Buffer QPCR Human No signal word. Reference Total RNA

Hazard statements

RNase-Free DNase I No known significant effects or critical hazards. (Lyophilized) ß-Mercaptoethanol H301 + H331 - Toxic if swallowed or if inhaled. H310 - Fatal in contact with skin. H315 - Causes skin irritation. H317 - May cause an allergic skin reaction. H318 - Causes serious eye damage. H361f - Suspected of damaging fertility. H373 - May cause damage to organs through prolonged or repeated exposure. (heart, liver) (oral) H410 - Very toxic to aquatic life with long lasting effects. De-paraffinization H226 - Flammable liquid and vapour. Reagent d-limonene H315 - Causes skin irritation. H317 - May cause an allergic skin reaction. H410 - Very toxic to aquatic life with long lasting effects. RNA Binding Buffer H302 + H332 - Harmful if swallowed or if inhaled. H412 - Harmful to aquatic life with long lasting effects. 1.67X High Salt Wash H302 + H332 - Harmful if swallowed or if inhaled. Buffer H412 - Harmful to aquatic life with long lasting effects. 5x Low Salt Wash Buffer No known significant effects or critical hazards. Elution Buffer No known significant effects or critical hazards. DNase Reconstitution No known significant effects or critical hazards. Buffer DNase Digestion Buffer H226 - Flammable liquid and vapour. Proteinase K No known significant effects or critical hazards. Proteinase K Digestion No known significant effects or critical hazards. Buffer QPCR Human No known significant effects or critical hazards. Reference Total RNA

Prevention

RNase-Free DNase I Not applicable. (Lyophilized) ß-Mercaptoethanol P280 - Wear protective gloves, protective clothing and eye or face protection. P273 - Avoid release to the environment. P262 - Do not get in eyes, on skin, or on clothing. P260 - Do not breathe vapour. De-paraffinization P280 - Wear protective gloves. Reagent d-limonene P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P273 - Avoid release to the environment. P261 - Avoid breathing vapour. RNA Binding Buffer P273 - Avoid release to the environment. P261 - Avoid breathing vapour. P270 - Do not eat, drink or smoke when using this product. P264 - Wash thoroughly after handling. 1.67X High Salt Wash P273 - Avoid release to the environment. Buffer P261 - Avoid breathing vapour. P270 - Do not eat, drink or smoke when using this product. P264 - Wash thoroughly after handling. 5x Low Salt Wash Buffer Not applicable. Elution Buffer Not applicable. DNase Reconstitution Not applicable. Buffer DNase Digestion Buffer P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. Proteinase K Not applicable. Proteinase K Digestion Not applicable. Buffer QPCR Human Not applicable. Reference Total RNA

Response

RNase-Free DNase I Not applicable. (Lyophilized) ß-Mercaptoethanol P391 - Collect spillage. De-paraffinization P391 - Collect spillage. Reagent d-limonene RNA Binding Buffer P304 + P312 - IF INHALED: Call a POISON CENTER or doctor if you feel unwell. 1.67X High Salt Wash P304 + P312 - IF INHALED: Call a POISON CENTER or Buffer doctor if you feel unwell. 5x Low Salt Wash Buffer Not applicable. Elution Buffer Not applicable. DNase Reconstitution Not applicable. Buffer DNase Digestion Buffer Not applicable. Proteinase K Not applicable. Proteinase K Digestion Not applicable. Buffer QPCR Human Not applicable. Reference Total RNA

Storage

RNase-Free DNase I Not applicable. (Lyophilized) ß-Mercaptoethanol Not applicable. De-paraffinization Not applicable. Reagent d-limonene RNA Binding Buffer Not applicable. 1.67X High Salt Wash Not applicable. Buffer 5x Low Salt Wash Buffer Not applicable. Elution Buffer Not applicable. DNase Reconstitution Not applicable. Buffer DNase Digestion Buffer Not applicable. Proteinase K Not applicable. Proteinase K Digestion Not applicable. Buffer QPCR Human Not applicable. Reference Total RNA

Disposal

RNase-Free DNase I Not applicable. (Lyophilized) ß-Mercaptoethanol P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. De-paraffinization P501 - Dispose of contents and container in accordance Reagent d-limonene with all local, regional, national and international regulations. RNA Binding Buffer P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. 1.67X High Salt Wash P501 - Dispose of contents and container in accordance Buffer with all local, regional, national and international regulations. 5x Low Salt Wash Buffer Not applicable. Elution Buffer Not applicable. DNase Reconstitution Not applicable. Buffer DNase Digestion Buffer P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. Proteinase K Not applicable. Proteinase K Digestion Not applicable. Buffer QPCR Human Not applicable. Reference Total RNA

Hazardous Ingredients

RNA Binding Buffer - salts of thiocyanic acid 1.67X High Salt Wash - salts of thiocyanic acid Buffer DNase Digestion Buffer Not applicable. Proteinase K Digestion Not applicable. Buffer

Supplemental label elements

RNase-Free DNase I Not applicable. elements (Lyophilized) ß-Mercaptoethanol Not applicable. De-paraffinization Not applicable. Reagent d-limonene RNA Binding Buffer Not applicable. 1.67X High Salt Wash Not applicable. Buffer 5x Low Salt Wash Buffer Not applicable. Elution Buffer Not applicable. DNase Reconstitution Not applicable. Buffer DNase Digestion Buffer Not applicable. Proteinase K Not applicable. Proteinase K Digestion Safety data sheet available on request. Buffer QPCR Human Not applicable. Reference Total RNA Annex XVII - Restrictions : RNase-Free DNase I Not applicable. on the manufacture, (Lyophilized) placing on the market ß-Mercaptoethanol Not applicable. and use of certain De-paraffinization Not applicable. dangerous substances, Reagent d-limonene mixtures and articles RNA Binding Buffer Not applicable. 1.67X High Salt Wash Not applicable. Buffer 5x Low Salt Wash Buffer Not applicable. Elution Buffer Not applicable. DNase Reconstitution Not applicable. Buffer DNase Digestion Buffer Not applicable. Proteinase K Not applicable. Proteinase K Digestion Not applicable. Buffer QPCR Human Not applicable. Reference Total RNA

Special packaging requirements

Tactile warning of RNase-Free DNase I Not applicable. danger (Lyophilized) ß-Mercaptoethanol Not applicable. De-paraffinization Not applicable. Reagent d-limonene RNA Binding Buffer Not applicable. 1.67X High Salt Wash Not applicable. Buffer 5x Low Salt Wash Buffer Not applicable. Elution Buffer Not applicable. DNase Reconstitution Not applicable. Buffer DNase Digestion Buffer Not applicable. Proteinase K Not applicable. Proteinase K Digestion Not applicable. Buffer QPCR Human Not applicable. Reference Total RNA

2.3 Other hazards

Product meets the

PBT Substances

P B T

vPvB Substances

vP vB criteria for PBT or vPvB according to RNase-Free Regulation (EC) No. DNase I

2.1 Classification of the substance or mixture

ß-Mercaptoethanol None known. De-paraffinization None known. Reagent d-limonene RNA Binding Buffer Causes digestive tract burns. 1.67X High Salt Wash Causes digestive tract burns. Buffer 5x Low Salt Wash Buffer None known. Elution Buffer None known. DNase Reconstitution None known. Buffer DNase Digestion Buffer None known. Proteinase K None known. Proteinase K Digestion None known. Buffer QPCR Human None known. Reference Total RNA