SureSelect XT Reagent Kit-HSQ/MSQ Automation- 96/480 Reactions-Revised Index

Hazard statements (CLP)

H319, H320, H335, H373

Code

Statements

H319

Causes serious eye irritation

2.1 Classification of the substance or mixture

OSHA/HCS status : Exo(-) Klenow This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). 10X End Repair Buffer While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910. 1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. 5X T4 DNA Ligase Buffer This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). Klenow DNA Polymerase This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). T4 DNA Ligase This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). T4 DNA Polymerase This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). T4 Polynucleotide Kinase This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). dNTP Mix While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910. 1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. 10x Klenow Polymerase While this material is not considered hazardous by the Buffer OSHA Hazard Communication Standard (29 CFR 1910. 1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. dATP While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910. 1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. SureSelect Adaptor Oligo While this material is not considered hazardous by the Mix OSHA Hazard Communication Standard (29 CFR 1910. 1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. SureSelect Primer While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910. 1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. SureSelect RNase Block This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). SureSelect Indexing Post- While this material is not considered hazardous by the Capture PCR (Forward) OSHA Hazard Communication Standard (29 CFR 1910. primer 1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. SureSelect Block 2 While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910. 1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. SureSelect Indexing Block 1 While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910. 1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. SureSelect Indexing Pre- While this material is not considered hazardous by the Capture PCR (Reverse) OSHA Hazard Communication Standard (29 CFR 1910. Primer 1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. SureSelect XT 8 bp Indexes While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910. 1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. SureSelect Indexing Block 3 While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910. 1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. SureSelect Hyb 3 While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910. 1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. SureSelect Wash Buffer 2 While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910. 1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. SureSelect Wash Buffer 1 While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910. 1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. SureSelect Binding Buffer While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910. 1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. SureSelect Hyb 4 While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910. 1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. SureSelect Hyb 2 This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). SureSelect Hyb 1 This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). Exo(-) Klenow H320 EYE IRRITATION - Category 2B 5X T4 DNA Ligase Buffer H319 EYE IRRITATION - Category 2A H335 SPECIFIC TARGET ORGAN TOXICITY (SINGLE EXPOSURE) (Respiratory tract irritation) - Category 3 Klenow DNA Polymerase H320 EYE IRRITATION - Category 2B T4 DNA Ligase H320 EYE IRRITATION - Category 2B T4 DNA Polymerase H320 EYE IRRITATION - Category 2B T4 Polynucleotide Kinase H320 EYE IRRITATION - Category 2B SureSelect RNase Block H320 EYE IRRITATION - Category 2B SureSelect Hyb 2 H319 EYE IRRITATION - Category 2A H373 SPECIFIC TARGET ORGAN TOXICITY (REPEATED EXPOSURE) (respiratory tract) - Category 2 SureSelect Hyb 1 H319 EYE IRRITATION - Category 2A Ingredients of unknown Exo(-) Klenow Percentage of the mixture consisting of ingredient toxicity (s) of unknown inhalation toxicity: 30 - 60% 10X End Repair Buffer Percentage of the mixture consisting of ingredient (s) of unknown dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 10 - 30% Percentage of the mixture consisting of ingredient (s) of unknown oral toxicity: 1 - 10% 5X T4 DNA Ligase Buffer Percentage of the mixture consisting of ingredient (s) of unknown dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 10 - 30% Percentage of the mixture consisting of ingredient (s) of unknown oral toxicity: 1 - 10% Klenow DNA Polymerase Percentage of the mixture consisting of ingredient (s) of unknown dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 30 - 60% Percentage of the mixture consisting of ingredient (s) of unknown oral toxicity: 1 - 10% T4 DNA Ligase Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 30 - 60% T4 DNA Polymerase Percentage of the mixture consisting of ingredient (s) of unknown dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 30 - 60% Percentage of the mixture consisting of ingredient (s) of unknown oral toxicity: 1 - 10% T4 Polynucleotide Kinase Percentage of the mixture consisting of ingredient (s) of unknown dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 30 - 60% Percentage of the mixture consisting of ingredient (s) of unknown oral toxicity: 1 - 10% dNTP Mix Percentage of the mixture consisting of ingredient (s) of unknown dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 1 - 10% Percentage of the mixture consisting of ingredient (s) of unknown oral toxicity: 1 - 10% 10x Klenow Polymerase Buffer Percentage of the mixture consisting of ingredient (s) of unknown dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 1 - 10% Percentage of the mixture consisting of ingredient (s) of unknown oral toxicity: 1 - 10% SureSelect RNase Block Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 30 - 60% SureSelect Hyb 3 Percentage of the mixture consisting of ingredient (s) of unknown dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 1 - 10% Percentage of the mixture consisting of ingredient (s) of unknown oral toxicity: 1 - 10% SureSelect Binding Buffer Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 1 - 10% SureSelect Hyb 4 Percentage of the mixture consisting of ingredient (s) of unknown dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 1 - 10% SureSelect Hyb 2 Percentage of the mixture consisting of ingredient (s) of unknown dermal toxicity: 10 - 30% SureSelect Hyb 1 Percentage of the mixture consisting of ingredient (s) of unknown dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 10 - 30% 10X End Repair Buffer Percentage of the mixture consisting of ingredient (s) of unknown hazards to the aquatic environment: 7.9% 5X T4 DNA Ligase Buffer Percentage of the mixture consisting of ingredient (s) of unknown hazards to the aquatic environment: 3.9% Klenow DNA Polymerase Percentage of the mixture consisting of ingredient (s) of unknown hazards to the aquatic environment: 2% T4 DNA Polymerase Percentage of the mixture consisting of ingredient (s) of unknown hazards to the aquatic environment: 2% T4 Polynucleotide Kinase Percentage of the mixture consisting of ingredient (s) of unknown hazards to the aquatic environment: 2% dNTP Mix Percentage of the mixture consisting of ingredient (s) of unknown hazards to the aquatic environment: 6% 10x Klenow Polymerase Buffer Percentage of the mixture consisting of ingredient (s) of unknown hazards to the aquatic environment: 7.9% SureSelect Hyb 3 Percentage of the mixture consisting of ingredient (s) of unknown hazards to the aquatic environment: 1% SureSelect Hyb 4 Percentage of the mixture consisting of ingredient (s) of unknown hazards to the aquatic environment: 1%

Hazard pictograms

5X T4 DNA Ligase Buffer SureSelect Hyb 2 SureSelect Hyb 1

Signal word

Exo(-) Klenow Warning 10X End Repair Buffer No signal word. 5X T4 DNA Ligase Buffer Warning Klenow DNA Polymerase Warning T4 DNA Ligase Warning T4 DNA Polymerase Warning T4 Polynucleotide Kinase Warning dNTP Mix No signal word. 10x Klenow Polymerase Buffer No signal word. dATP No signal word. SureSelect Adaptor Oligo Mix No signal word. SureSelect Primer No signal word. SureSelect RNase Block Warning SureSelect Indexing Post-Capture No signal word. PCR (Forward) primer SureSelect Block 2 No signal word. SureSelect Indexing Block 1 No signal word. SureSelect Indexing Pre-Capture No signal word. PCR (Reverse) Primer SureSelect XT 8 bp Indexes No signal word. SureSelect Indexing Block 3 No signal word. SureSelect Hyb 3 No signal word. SureSelect Wash Buffer 2 No signal word. SureSelect Wash Buffer 1 No signal word. SureSelect Binding Buffer No signal word. SureSelect Hyb 4 No signal word. SureSelect Hyb 2 Warning SureSelect Hyb 1 Warning

Hazard statements

Exo(-) Klenow H320 - Causes eye irritation. 10X End Repair Buffer No known significant effects or critical hazards. 5X T4 DNA Ligase Buffer H319 - Causes serious eye irritation. H335 - May cause respiratory irritation. Klenow DNA Polymerase H320 - Causes eye irritation. T4 DNA Ligase H320 - Causes eye irritation. T4 DNA Polymerase H320 - Causes eye irritation. T4 Polynucleotide Kinase H320 - Causes eye irritation. dNTP Mix No known significant effects or critical hazards. 10x Klenow Polymerase Buffer No known significant effects or critical hazards. dATP No known significant effects or critical hazards. SureSelect Adaptor Oligo Mix No known significant effects or critical hazards. SureSelect Primer No known significant effects or critical hazards. SureSelect RNase Block H320 - Causes eye irritation. SureSelect Indexing Post-Capture No known significant effects or critical hazards. PCR (Forward) primer SureSelect Block 2 No known significant effects or critical hazards. SureSelect Indexing Block 1 No known significant effects or critical hazards. SureSelect Indexing Pre-Capture No known significant effects or critical hazards. PCR (Reverse) Primer SureSelect XT 8 bp Indexes No known significant effects or critical hazards. SureSelect Indexing Block 3 No known significant effects or critical hazards. SureSelect Hyb 3 No known significant effects or critical hazards. SureSelect Wash Buffer 2 No known significant effects or critical hazards. SureSelect Wash Buffer 1 No known significant effects or critical hazards. SureSelect Binding Buffer No known significant effects or critical hazards. SureSelect Hyb 4 No known significant effects or critical hazards. SureSelect Hyb 2 H319 - Causes serious eye irritation. H373 - May cause damage to organs through prolonged or repeated exposure. (respiratory tract) SureSelect Hyb 1 H319 - Causes serious eye irritation.

Prevention

Exo(-) Klenow P264 - Wash hands thoroughly after handling. 10X End Repair Buffer Not applicable. 5X T4 DNA Ligase Buffer P280 - Wear eye or face protection. P271 - Use only outdoors or in a well-ventilated area. P261 - Avoid breathing vapor. P264 - Wash hands thoroughly after handling. Klenow DNA Polymerase P264 - Wash hands thoroughly after handling. T4 DNA Ligase P264 - Wash hands thoroughly after handling. T4 DNA Polymerase P264 - Wash hands thoroughly after handling. T4 Polynucleotide Kinase P264 - Wash hands thoroughly after handling. dNTP Mix Not applicable. 10x Klenow Polymerase Buffer Not applicable. dATP Not applicable. SureSelect Adaptor Oligo Mix Not applicable. SureSelect Primer Not applicable. SureSelect RNase Block P264 - Wash hands thoroughly after handling. SureSelect Indexing Post-Capture Not applicable. PCR (Forward) primer SureSelect Block 2 Not applicable. SureSelect Indexing Block 1 Not applicable. SureSelect Indexing Pre-Capture Not applicable. PCR (Reverse) Primer SureSelect XT 8 bp Indexes Not applicable. SureSelect Indexing Block 3 Not applicable. SureSelect Hyb 3 Not applicable. SureSelect Wash Buffer 2 Not applicable. SureSelect Wash Buffer 1 Not applicable. SureSelect Binding Buffer Not applicable. SureSelect Hyb 4 Not applicable. SureSelect Hyb 2 P280 - Wear eye or face protection. P260 - Do not breathe vapor. P264 - Wash hands thoroughly after handling. SureSelect Hyb 1 P280 - Wear eye or face protection. P264 - Wash hands thoroughly after handling.

Response

Exo(-) Klenow P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. 10X End Repair Buffer Not applicable. 5X T4 DNA Ligase Buffer P304 + P340 + P312 - IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER or physician if you feel unwell. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. Klenow DNA Polymerase P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. T4 DNA Ligase P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. T4 DNA Polymerase P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. T4 Polynucleotide Kinase P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. dNTP Mix Not applicable. 10x Klenow Polymerase Buffer Not applicable. dATP Not applicable. SureSelect Adaptor Oligo Mix Not applicable. SureSelect Primer Not applicable. SureSelect RNase Block P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. SureSelect Indexing Post-Capture Not applicable. PCR (Forward) primer SureSelect Block 2 Not applicable. SureSelect Indexing Block 1 Not applicable. SureSelect Indexing Pre-Capture Not applicable. PCR (Reverse) Primer SureSelect XT 8 bp Indexes Not applicable. SureSelect Indexing Block 3 Not applicable. SureSelect Hyb 3 Not applicable. SureSelect Wash Buffer 2 Not applicable. SureSelect Wash Buffer 1 Not applicable. SureSelect Binding Buffer Not applicable. SureSelect Hyb 4 Not applicable. SureSelect Hyb 2 P314 - Get medical attention if you feel unwell. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. SureSelect Hyb 1 P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention.

Storage

Exo(-) Klenow Not applicable. 10X End Repair Buffer Not applicable. 5X T4 DNA Ligase Buffer P405 - Store locked up. Klenow DNA Polymerase Not applicable. T4 DNA Ligase Not applicable. T4 DNA Polymerase Not applicable. T4 Polynucleotide Kinase Not applicable. dNTP Mix Not applicable. 10x Klenow Polymerase Buffer Not applicable. dATP Not applicable. SureSelect Adaptor Oligo Mix Not applicable. SureSelect Primer Not applicable. SureSelect RNase Block Not applicable. SureSelect Indexing Post-Capture Not applicable. PCR (Forward) primer SureSelect Block 2 Not applicable. SureSelect Indexing Block 1 Not applicable. SureSelect Indexing Pre-Capture Not applicable. PCR (Reverse) Primer SureSelect XT 8 bp Indexes Not applicable. SureSelect Indexing Block 3 Not applicable. SureSelect Hyb 3 Not applicable. SureSelect Wash Buffer 2 Not applicable. SureSelect Wash Buffer 1 Not applicable. SureSelect Binding Buffer Not applicable. SureSelect Hyb 4 Not applicable. SureSelect Hyb 2 Not applicable. SureSelect Hyb 1 Not applicable.

Disposal

Exo(-) Klenow Not applicable. 10X End Repair Buffer Not applicable. 5X T4 DNA Ligase Buffer P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. Klenow DNA Polymerase Not applicable. T4 DNA Ligase Not applicable. T4 DNA Polymerase Not applicable. T4 Polynucleotide Kinase Not applicable. dNTP Mix Not applicable. 10x Klenow Polymerase Buffer Not applicable. dATP Not applicable. SureSelect Adaptor Oligo Mix Not applicable. SureSelect Primer Not applicable. SureSelect RNase Block Not applicable. SureSelect Indexing Post-Capture Not applicable. PCR (Forward) primer SureSelect Block 2 Not applicable. SureSelect Indexing Block 1 Not applicable. SureSelect Indexing Pre-Capture Not applicable. PCR (Reverse) Primer SureSelect XT 8 bp Indexes Not applicable. SureSelect Indexing Block 3 Not applicable. SureSelect Hyb 3 Not applicable. SureSelect Wash Buffer 2 Not applicable. SureSelect Wash Buffer 1 Not applicable. SureSelect Binding Buffer Not applicable. SureSelect Hyb 4 Not applicable. SureSelect Hyb 2 P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. SureSelect Hyb 1 Not applicable.

Supplemental label elements

Exo(-) Klenow None known. elements 10X End Repair Buffer None known. 5X T4 DNA Ligase Buffer None known. Klenow DNA Polymerase None known. T4 DNA Ligase None known. T4 DNA Polymerase None known. T4 Polynucleotide Kinase None known. dNTP Mix None known. 10x Klenow Polymerase Buffer None known. dATP None known. SureSelect Adaptor Oligo Mix None known. SureSelect Primer None known. SureSelect RNase Block None known. SureSelect Indexing Post-Capture None known. PCR (Forward) primer SureSelect Block 2 None known. SureSelect Indexing Block 1 None known. SureSelect Indexing Pre-Capture None known. PCR (Reverse) Primer SureSelect XT 8 bp Indexes None known. SureSelect Indexing Block 3 None known. SureSelect Hyb 3 None known. SureSelect Wash Buffer 2 None known. SureSelect Wash Buffer 1 None known. SureSelect Binding Buffer None known. SureSelect Hyb 4 None known. SureSelect Hyb 2 None known. SureSelect Hyb 1 None known.

2.3 Other hazards

Hazards not otherwise : Exo(-) Klenow None known. classified 10X End Repair Buffer None known. 5X T4 DNA Ligase Buffer None known. Klenow DNA Polymerase None known. T4 DNA Ligase None known. T4 DNA Polymerase None known. T4 Polynucleotide Kinase None known. dNTP Mix None known. 10x Klenow Polymerase Buffer None known. dATP None known. SureSelect Adaptor Oligo Mix None known. SureSelect Primer None known. SureSelect RNase Block None known. SureSelect Indexing Post-Capture None known. PCR (Forward) primer SureSelect Block 2 None known. SureSelect Indexing Block 1 None known. SureSelect Indexing Pre-Capture None known. PCR (Reverse) Primer SureSelect XT 8 bp Indexes None known. SureSelect Indexing Block 3 None known. SureSelect Hyb 3 None known. SureSelect Wash Buffer 2 None known. SureSelect Wash Buffer 1 None known. SureSelect Binding Buffer None known. SureSelect Hyb 4 None known. SureSelect Hyb 2 None known. SureSelect Hyb 1 None known.