QuikChange Lightning Multi Site-Directed Mutagenesis Kit, Part Number 210513 : 210513

Hazard statements (CLP)

H227, H317, H318, H319, H320, H361, H373, H412

Code

Statements

H227

Combustible liquid

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

QuikSolution H227 FLAMMABLE LIQUIDS - Category 4 H320 EYE IRRITATION - Category 2B QuikChange Lightning Multi Enzyme H320 EYE IRRITATION - Category 2B 10X QuikChange Lightning Multi Buffer H319 EYE IRRITATION - Category 2A H412 AQUATIC HAZARD (LONG-TERM) - Category 3 Dpn I Enzyme H320 EYE IRRITATION - Category 2B XL10-Gold Ultracompetent cells H320 EYE IRRITATION - Category 2B XL10-Gold 2-Mercaptoethanol H318 SERIOUS EYE DAMAGE - Category 1 H317 SKIN SENSITIZATION - Category 1 H361 TOXIC TO REPRODUCTION - Category 2 H373 SPECIFIC TARGET ORGAN TOXICITY (REPEATED EXPOSURE) - Category 2 H412 AQUATIC HAZARD (LONG-TERM) - Category 3 XL10-Gold Ultracompetent cells Percentage of the mixture consisting of ingredient (s) of unknown hazards to the aquatic environment: 5%

Hazard pictograms

10X QuikChange Lightning Multi Buffer XL10-Gold 2-Mercaptoethanol

Signal word

QuikSolution Warning QuikChange Lightning Multi Warning Enzyme 10X QuikChange Lightning Multi Warning Buffer dNTP Mix No signal word. Dpn I Enzyme Warning QuikChange Multi Control No signal word. Template QuikChange Multi Ctl. Primer Mix No signal word. XL10-Gold Ultracompetent cells Warning XL10-Gold 2-Mercaptoethanol Danger pUC 18 DNA Control Plasmid No signal word.

Hazard statements

QuikSolution H227 - Combustible liquid. H320 - Causes eye irritation. QuikChange Lightning Multi H320 - Causes eye irritation. Enzyme 10X QuikChange Lightning Multi H319 - Causes serious eye irritation. Buffer H412 - Harmful to aquatic life with long lasting effects. dNTP Mix No known significant effects or critical hazards. Dpn I Enzyme H320 - Causes eye irritation. QuikChange Multi Control No known significant effects or critical hazards. Template QuikChange Multi Ctl. Primer Mix No known significant effects or critical hazards. XL10-Gold Ultracompetent cells H320 - Causes eye irritation. XL10-Gold 2-Mercaptoethanol H317 - May cause an allergic skin reaction. H318 - Causes serious eye damage. H361 - Suspected of damaging fertility or the unborn child. H373 - May cause damage to organs through prolonged or repeated exposure. H412 - Harmful to aquatic life with long lasting effects. pUC 18 DNA Control Plasmid No known significant effects or critical hazards.

Prevention

QuikSolution P210 - Keep away from flames and hot surfaces. No smoking. QuikChange Lightning Multi Not applicable. Enzyme 10X QuikChange Lightning Multi P280 - Wear eye or face protection. Buffer P273 - Avoid release to the environment. dNTP Mix Not applicable. Dpn I Enzyme Not applicable. QuikChange Multi Control Not applicable. Template QuikChange Multi Ctl. Primer Mix Not applicable. XL10-Gold Ultracompetent cells Not applicable. XL10-Gold 2-Mercaptoethanol P201 - Obtain special instructions before use. P280 - Wear protective gloves, protective clothing and eye or face protection. P273 - Avoid release to the environment. P260 - Do not breathe vapor. pUC 18 DNA Control Plasmid Not applicable.

Response

QuikSolution P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical advice or attention. QuikChange Lightning Multi P305 + P351 + P338 - IF IN EYES: Rinse Enzyme cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical advice or attention. 10X QuikChange Lightning Multi P305 + P351 + P338 - IF IN EYES: Rinse Buffer cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical advice or attention. dNTP Mix Not applicable. Dpn I Enzyme P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical advice or attention. QuikChange Multi Control Not applicable. Template QuikChange Multi Ctl. Primer Mix Not applicable. XL10-Gold Ultracompetent cells P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical advice or attention. XL10-Gold 2-Mercaptoethanol P308 + P313 - IF exposed or concerned: Get medical advice or attention. P363 - Wash contaminated clothing before reuse. P302 + P352 - IF ON SKIN: Wash with plenty of water. P333 + P313 - If skin irritation or rash occurs: Get medical advice or attention. P305 + P351 + P338, P310 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor. pUC 18 DNA Control Plasmid Not applicable.

Storage

QuikSolution P403 + P235 - Store in a well-ventilated place. Keep cool. QuikChange Lightning Multi Not applicable. Enzyme 10X QuikChange Lightning Multi Not applicable. Buffer dNTP Mix Not applicable. Dpn I Enzyme Not applicable. QuikChange Multi Control Not applicable. Template QuikChange Multi Ctl. Primer Mix Not applicable. XL10-Gold Ultracompetent cells Not applicable. XL10-Gold 2-Mercaptoethanol Not applicable. pUC 18 DNA Control Plasmid Not applicable.

Disposal

QuikSolution P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. QuikChange Lightning Multi Not applicable. Enzyme 10X QuikChange Lightning Multi P501 - Dispose of contents and container in Buffer accordance with all local, regional, national and international regulations. dNTP Mix Not applicable. Dpn I Enzyme Not applicable. QuikChange Multi Control Not applicable. Template QuikChange Multi Ctl. Primer Mix Not applicable. XL10-Gold Ultracompetent cells Not applicable. XL10-Gold 2-Mercaptoethanol P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. pUC 18 DNA Control Plasmid Not applicable.

Supplemental label elements

QuikSolution None known. elements QuikChange Lightning Multi None known. Enzyme 10X QuikChange Lightning Multi None known. Buffer dNTP Mix None known. Dpn I Enzyme None known. QuikChange Multi Control None known. Template QuikChange Multi Ctl. Primer Mix None known. XL10-Gold Ultracompetent cells None known. XL10-Gold 2-Mercaptoethanol None known. pUC 18 DNA Control Plasmid None known.

2.3 Other hazards

Hazards not otherwise : QuikSolution None known. classified QuikChange Lightning Multi None known. Enzyme 10X QuikChange Lightning Multi None known. Buffer dNTP Mix None known. Dpn I Enzyme None known. QuikChange Multi Control None known. Template QuikChange Multi Ctl. Primer Mix None known. XL10-Gold Ultracompetent cells None known. XL10-Gold 2-Mercaptoethanol None known. pUC 18 DNA Control Plasmid None known.