HaloPlex Target Enrichment Kits - ION - 96 reactions G9902B, G9912B

Hazard statements (CLP)

H319, H320, H360

Code

Statements

H319

Causes serious eye irritation

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

DNA Ligase H320 EYE IRRITATION - Category 2B Wash Solution H319 EYE IRRITATION - Category 2A H360 TOXIC TO REPRODUCTION (Unborn child) - Category 1B Hybridization Solution H319 EYE IRRITATION - Category 2A H360 TOXIC TO REPRODUCTION (Unborn child) - Category 1B Enzyme Strip 1 H320 EYE IRRITATION - Category 2B Enzyme Strip 2 H320 EYE IRRITATION - Category 2B Ingredients of unknown BSA Solution Percentage of the mixture consisting of ingredient toxicity (s) of unknown inhalation toxicity: 1 - 10% DNA Ligase Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 30 - 60% Wash Solution Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 1 - 10% Capture Solution Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 1 - 10% Hybridization Solution Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 10 - 30% Enzyme Strip 1 Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 30 - 60% Enzyme Strip 2 Percentage of the mixture consisting of ingredient (s) of unknown inhalation toxicity: 30 - 60%

2.2 Label elements

Date of Issue 02/14/2018

Hazard pictograms

Wash Solution Hybridization Solution

Signal word

RE Buffer No signal word. SSC Buffer No signal word. BSA Solution No signal word. DNA Ligase Warning Ligation Solution No signal word. Wash Solution Danger Capture Solution No signal word. HaloPlex ION Primer 1 No signal word. HaloPlex ION Primer 2 No signal word. HaloPlex Barcoding Primer No signal word. Cassettes 1-48 Hybridization Solution Danger Enrichment Control DNA No signal word. HaloPlex Magnetic Beads No signal word. HaloPlex Probe No signal word. Enzyme Strip 1 Warning Enzyme Strip 2 Warning

Hazard statements

RE Buffer No known significant effects or critical hazards. SSC Buffer No known significant effects or critical hazards. BSA Solution No known significant effects or critical hazards. DNA Ligase H320 - Causes eye irritation. Ligation Solution No known significant effects or critical hazards. Wash Solution H319 - Causes serious eye irritation. H360 - May damage the unborn child. Capture Solution No known significant effects or critical hazards. HaloPlex ION Primer 1 No known significant effects or critical hazards. HaloPlex ION Primer 2 No known significant effects or critical hazards. HaloPlex Barcoding Primer No known significant effects or critical hazards. Cassettes 1-48 Hybridization Solution H319 - Causes serious eye irritation. H360 - May damage the unborn child. Enrichment Control DNA No known significant effects or critical hazards. HaloPlex Magnetic Beads No known significant effects or critical hazards. HaloPlex Probe No known significant effects or critical hazards. Enzyme Strip 1 H320 - Causes eye irritation. Enzyme Strip 2 H320 - Causes eye irritation.

Prevention

RE Buffer Not applicable. SSC Buffer Not applicable. BSA Solution Not applicable. DNA Ligase P264 - Wash hands thoroughly after handling. Ligation Solution Not applicable. Wash Solution P201 - Obtain special instructions before use. P202 - Do not handle until all safety precautions have been read and understood. P280 - Wear protective gloves. Wear eye or face protection. Wear protective clothing. P264 - Wash hands thoroughly after handling. Date of Issue 02/14/2018 Capture Solution Not applicable. HaloPlex ION Primer 1 Not applicable. HaloPlex ION Primer 2 Not applicable. HaloPlex Barcoding Primer Not applicable. Cassettes 1-48 Hybridization Solution P201 - Obtain special instructions before use. P202 - Do not handle until all safety precautions have been read and understood. P280 - Wear protective gloves. Wear eye or face protection. Wear protective clothing. P264 - Wash hands thoroughly after handling. Enrichment Control DNA Not applicable. HaloPlex Magnetic Beads Not applicable. HaloPlex Probe Not applicable. Enzyme Strip 1 P264 - Wash hands thoroughly after handling. Enzyme Strip 2 P264 - Wash hands thoroughly after handling.

Response

RE Buffer Not applicable. SSC Buffer Not applicable. BSA Solution Not applicable. DNA Ligase P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. Ligation Solution Not applicable. Wash Solution P308 + P313 - IF exposed or concerned: Get medical attention. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. Capture Solution Not applicable. HaloPlex ION Primer 1 Not applicable. HaloPlex ION Primer 2 Not applicable. HaloPlex Barcoding Primer Not applicable. Cassettes 1-48 Hybridization Solution P308 + P313 - IF exposed or concerned: Get medical attention. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. Enrichment Control DNA Not applicable. HaloPlex Magnetic Beads Not applicable. HaloPlex Probe Not applicable. Enzyme Strip 1 P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. Enzyme Strip 2 P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue Date of Issue 02/14/2018 rinsing. P337 + P313 - If eye irritation persists: Get medical attention.

Storage

RE Buffer Not applicable. SSC Buffer Not applicable. BSA Solution Not applicable. DNA Ligase Not applicable. Ligation Solution Not applicable. Wash Solution P405 - Store locked up. Capture Solution Not applicable. HaloPlex ION Primer 1 Not applicable. HaloPlex ION Primer 2 Not applicable. HaloPlex Barcoding Primer Not applicable. Cassettes 1-48 Hybridization Solution P405 - Store locked up. Enrichment Control DNA Not applicable. HaloPlex Magnetic Beads Not applicable. HaloPlex Probe Not applicable. Enzyme Strip 1 Not applicable. Enzyme Strip 2 Not applicable.

Disposal

RE Buffer Not applicable. SSC Buffer Not applicable. BSA Solution Not applicable. DNA Ligase Not applicable. Ligation Solution Not applicable. Wash Solution P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. Capture Solution Not applicable. HaloPlex ION Primer 1 Not applicable. HaloPlex ION Primer 2 Not applicable. HaloPlex Barcoding Primer Not applicable. Cassettes 1-48 Hybridization Solution P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. Enrichment Control DNA Not applicable. HaloPlex Magnetic Beads Not applicable. HaloPlex Probe Not applicable. Enzyme Strip 1 Not applicable. Enzyme Strip 2 Not applicable.

Supplemental label elements

RE Buffer None known. elements SSC Buffer None known. BSA Solution None known. DNA Ligase None known. Ligation Solution None known. Wash Solution None known. Capture Solution None known. HaloPlex ION Primer 1 None known. HaloPlex ION Primer 2 None known. HaloPlex Barcoding Primer None known. Cassettes 1-48 Hybridization Solution None known. Enrichment Control DNA None known. HaloPlex Magnetic Beads None known. HaloPlex Probe None known. Enzyme Strip 1 None known. Enzyme Strip 2 None known. Date of Issue 02/14/2018

2.3 Other hazards

Hazards not otherwise : RE Buffer None known. classified SSC Buffer None known. BSA Solution None known. DNA Ligase None known. Ligation Solution None known. Wash Solution None known. Capture Solution None known. HaloPlex ION Primer 1 None known. HaloPlex ION Primer 2 None known. HaloPlex Barcoding Primer None known. Cassettes 1-48 Hybridization Solution None known. Enrichment Control DNA None known. HaloPlex Magnetic Beads None known. HaloPlex Probe None known. Enzyme Strip 1 None known. Enzyme Strip 2 None known.