Absolutely RNA Nanoprep Kit, Part Number 400753

Hazard statements (CLP)

H226, H227, H301, H301+H331, H302, H302+H332, H310, H314, H315, H317, H318, H319, H320, H331, H332, H335, H336, H361, H373, H400, H411, H412

Code

Statements

H226

Flammable liquid and vapour

2.1 Classification of the substance or mixture

OSHA/HCS status : RNase-Free DNase I This material is considered hazardous by the OSHA (Lyophilized) Hazard Communication Standard (29 CFR 1910.1200). ß-Mercaptoethanol This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). Lysis Buffer This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). 1.67X High Salt Wash Buffer This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). 5x Low Salt Wash Buffer While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. Elution Buffer While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this SDS contains valuable information critical to the safe handling and proper use of the product. This SDS should be retained and available for employees and other users of this product. DNase Reconstitution Buffer This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). DNase Digestion Buffer This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). RNase-Free DNase I (Lyophilized) COMBUSTIBLE DUSTS ß-Mercaptoethanol H227 FLAMMABLE LIQUIDS - Category 4 H301 ACUTE TOXICITY (oral) - Category 3 H310 ACUTE TOXICITY (dermal) - Category 2 H331 ACUTE TOXICITY (inhalation) - Category 3 H315 SKIN IRRITATION - Category 2 H318 SERIOUS EYE DAMAGE - Category 1 H317 SKIN SENSITIZATION - Category 1A H361 TOXIC TO REPRODUCTION - Category 2 H335 SPECIFIC TARGET ORGAN TOXICITY (SINGLE EXPOSURE) (Respiratory tract irritation) - Category 3 H373 SPECIFIC TARGET ORGAN TOXICITY (REPEATED EXPOSURE) - Category 2 H400 AQUATIC HAZARD (ACUTE) - Category 1 H411 AQUATIC HAZARD (LONG-TERM) - Category 2 Lysis Buffer H302 ACUTE TOXICITY (oral) - Category 4 H332 ACUTE TOXICITY (inhalation) - Category 4 H314 SKIN CORROSION - Category 1C H318 SERIOUS EYE DAMAGE - Category 1 H412 AQUATIC HAZARD (LONG-TERM) - Category 3 1.67X High Salt Wash Buffer H302 ACUTE TOXICITY (oral) - Category 4 H332 ACUTE TOXICITY (inhalation) - Category 4 H314 SKIN CORROSION - Category 1C H318 SERIOUS EYE DAMAGE - Category 1 H412 AQUATIC HAZARD (LONG-TERM) - Category 3 DNase Reconstitution Buffer H320 EYE IRRITATION - Category 2B DNase Digestion Buffer H226 FLAMMABLE LIQUIDS - Category 3 H319 EYE IRRITATION - Category 2A H336 SPECIFIC TARGET ORGAN TOXICITY (SINGLE EXPOSURE) (Narcotic effects) - Category 3 Ingredients of unknown 1.67X High Salt Wash Buffer Percentage of the mixture consisting of ingredient toxicity (s) of unknown acute inhalation toxicity: 1 - 10%

Hazard pictograms

ß-Mercaptoethanol Lysis Buffer 1.67X High Salt Wash Buffer DNase Digestion Buffer

Signal word

RNase-Free DNase I (Lyophilized) Warning ß-Mercaptoethanol Danger Lysis Buffer Danger 1.67X High Salt Wash Buffer Danger 5x Low Salt Wash Buffer No signal word. Elution Buffer No signal word. DNase Reconstitution Buffer Warning DNase Digestion Buffer Warning

Hazard statements

RNase-Free DNase I (Lyophilized) May form combustible dust concentrations in air. ß-Mercaptoethanol H227 - Combustible liquid. H301 + H331 - Toxic if swallowed or if inhaled. H310 - Fatal in contact with skin. H315 - Causes skin irritation. H317 - May cause an allergic skin reaction. H318 - Causes serious eye damage. H335 - May cause respiratory irritation. H361 - Suspected of damaging fertility or the unborn child. H373 - May cause damage to organs through prolonged or repeated exposure. (heart, liver) (oral) H400 - Very toxic to aquatic life. H411 - Toxic to aquatic life with long lasting effects. Lysis Buffer H302 + H332 - Harmful if swallowed or if inhaled. H314 - Causes severe skin burns and eye damage. H412 - Harmful to aquatic life with long lasting effects. 1.67X High Salt Wash Buffer H302 + H332 - Harmful if swallowed or if inhaled. H314 - Causes severe skin burns and eye damage. H412 - Harmful to aquatic life with long lasting effects. 5x Low Salt Wash Buffer No known significant effects or critical hazards. Elution Buffer No known significant effects or critical hazards. DNase Reconstitution Buffer H320 - Causes eye irritation. DNase Digestion Buffer H226 - Flammable liquid and vapor. H319 - Causes serious eye irritation. H336 - May cause drowsiness or dizziness.

Prevention

RNase-Free DNase I (Lyophilized) Not applicable. ß-Mercaptoethanol P280 - Wear protective gloves, protective clothing and eye or face protection. P210 - Keep away from flames and hot surfaces. No smoking. P273 - Avoid release to the environment. Lysis Buffer P280 - Wear protective gloves, protective clothing and eye or face protection. 1.67X High Salt Wash Buffer P280 - Wear protective gloves, protective clothing and eye or face protection. 5x Low Salt Wash Buffer Not applicable. Elution Buffer Not applicable. DNase Reconstitution Buffer Not applicable. DNase Digestion Buffer P280 - Wear eye or face protection. P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P241 - Use explosion-proof electrical, ventilating or lighting equipment.

Response

RNase-Free DNase I (Lyophilized) Not applicable. ß-Mercaptoethanol P391 - Collect spillage. Lysis Buffer P304 + P310 - IF INHALED: Immediately call a POISON CENTER or doctor. P301 + P310 - IF SWALLOWED: Immediately call a POISON CENTER or doctor. P303 + P361 + P353, P310 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. Immediately call a POISON CENTER or doctor. 1.67X High Salt Wash Buffer P304 + P310 - IF INHALED: Immediately call a POISON CENTER or doctor. P301 + P310 - IF SWALLOWED: Immediately call a POISON CENTER or doctor. P303 + P361 + P353, P310 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. Immediately call a POISON CENTER or doctor. 5x Low Salt Wash Buffer Not applicable. Elution Buffer Not applicable. DNase Reconstitution Buffer P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical advice or attention. DNase Digestion Buffer P304 + P312 - IF INHALED: Call a POISON CENTER or doctor if you feel unwell.

Storage

RNase-Free DNase I (Lyophilized) Not applicable. ß-Mercaptoethanol P403 + P235 - Store in a well-ventilated place. Keep cool. Lysis Buffer Not applicable. 1.67X High Salt Wash Buffer Not applicable. 5x Low Salt Wash Buffer Not applicable. Elution Buffer Not applicable. DNase Reconstitution Buffer Not applicable. DNase Digestion Buffer P403 + P235 - Store in a well-ventilated place. Keep cool.

Disposal

RNase-Free DNase I (Lyophilized) Not applicable. ß-Mercaptoethanol P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. Lysis Buffer P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. 1.67X High Salt Wash Buffer P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. 5x Low Salt Wash Buffer Not applicable. Elution Buffer Not applicable. DNase Reconstitution Buffer Not applicable. DNase Digestion Buffer P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations.

Supplemental label elements

RNase-Free DNase I (Lyophilized) Keep container tightly closed. Keep away from elements heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. Prevent dust accumulation. ß-Mercaptoethanol None known. Lysis Buffer Keep container tightly closed. Do not breathe vapor or spray. Do not taste or swallow. Use only with adequate ventilation. Wash thoroughly after handling. 1.67X High Salt Wash Buffer Keep container tightly closed. Do not breathe vapor or spray. Do not taste or swallow. Use only with adequate ventilation. Wash thoroughly after handling. 5x Low Salt Wash Buffer None known. Elution Buffer None known. DNase Reconstitution Buffer None known. DNase Digestion Buffer Avoid contact with skin and clothing. Wash thoroughly after handling.

2.3 Other hazards

RNase-Free DNase I (Lyophilized) None known. ß-Mercaptoethanol None known. Lysis Buffer Causes respiratory tract burns. Causes digestive tract burns. 1.67X High Salt Wash Buffer Causes respiratory tract burns. Causes digestive tract burns. 5x Low Salt Wash Buffer None known. Elution Buffer None known. DNase Reconstitution Buffer None known. DNase Digestion Buffer Prolonged or repeated contact may dry skin and cause irritation.