Absolutely RNA FFPE Kit, Part Number 400809 400809

Hazard statements (CLP)

H226, H227, H301, H302, H302+H332, H310, H310+H330, H315, H315+H320, H317, H318, H319, H320, H330, H332, H335, H336, H373

Code

Statements

H226

Flammable liquid and vapour

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

RNA Binding Buffer H302 ACUTE TOXICITY (oral) - Category 4 H332 ACUTE TOXICITY (inhalation) - Category 4 1.67x High-Salt Wash Buffer H302 ACUTE TOXICITY (oral) - Category 4 H332 ACUTE TOXICITY (inhalation) - Category 4 Beta-mercaptoethanol H227 FLAMMABLE LIQUIDS - Category 4 H301 ACUTE TOXICITY (oral) - Category 3 H310 ACUTE TOXICITY (dermal) - Category 2 H330 ACUTE TOXICITY (inhalation) - Category 2 H315 SKIN CORROSION/IRRITATION - Category 2 H318 SERIOUS EYE DAMAGE/ EYE IRRITATION - Category 1 H317 SKIN SENSITIZATION - Category 1 H335 SPECIFIC TARGET ORGAN TOXICITY (SINGLE EXPOSURE) (Respiratory tract irritation) - Category 3 Reconstitution Buffer H320 SERIOUS EYE DAMAGE/ EYE IRRITATION - Category 2B Digestion Buffer H226 FLAMMABLE LIQUIDS - Category 3 H319 SERIOUS EYE DAMAGE/ EYE IRRITATION - Category 2A H335 SPECIFIC TARGET ORGAN TOXICITY (SINGLE EXPOSURE) (Respiratory tract irritation) - Category 3 H336 SPECIFIC TARGET ORGAN TOXICITY (SINGLE EXPOSURE) (Narcotic effects) - Category 3 H373 SPECIFIC TARGET ORGAN TOXICITY (REPEATED EXPOSURE) - Category 2 Proteinase K H320 SERIOUS EYE DAMAGE/ EYE IRRITATION - Category 2B De-paraffinization Reagent (d- limonene) H226 FLAMMABLE LIQUIDS - Category 3 H315 SKIN CORROSION/IRRITATION - Category 2 H320 SERIOUS EYE DAMAGE/ EYE IRRITATION - Category 2B H317 SKIN SENSITIZATION - Category 1 Ingredients of unknown RNA Binding Buffer Not applicable. toxicity 1.67x High-Salt Wash Buffer Percentage of the mixture consisting of ingredient (s) of unknown toxicity: 1.3% 5x Low-Salt Wash Buffer Not applicable. Elution Buffer Not applicable. Beta-mercaptoethanol Not applicable. Deoxyribonuclease I enzyme Not applicable. Reconstitution Buffer Not applicable. Digestion Buffer Percentage of the mixture consisting of ingredient (s) of unknown toxicity: 3% Proteinase K Not applicable. Proteinase K Digestion Buffer Not applicable. Stratagene QPCR Human Not applicable. Reference Total RNA De-paraffinization Reagent (d- Not applicable. limonene)

Signal word

RNA Binding Buffer Warning 1.67x High-Salt Wash Buffer Warning 5x Low-Salt Wash Buffer No signal word. Elution Buffer No signal word. Beta-mercaptoethanol Danger Deoxyribonuclease I enzyme No signal word. Reconstitution Buffer Warning Digestion Buffer Warning Proteinase K Warning Proteinase K Digestion Buffer No signal word. Stratagene QPCR Human No signal word. Reference Total RNA De-paraffinization Reagent (d- Warning limonene)

Hazard statements

RNA Binding Buffer H302 + H332 - Harmful if swallowed or if inhaled. 1.67x High-Salt Wash Buffer H302 + H332 - Harmful if swallowed or if inhaled. 5x Low-Salt Wash Buffer No known significant effects or critical hazards. Elution Buffer No known significant effects or critical hazards. Beta-mercaptoethanol H227 - Combustible liquid. H310 + H330 - Fatal in contact with skin or if inhaled. H301 - Toxic if swallowed. H318 - Causes serious eye damage. H315 - Causes skin irritation. H317 - May cause an allergic skin reaction. H335 - May cause respiratory irritation. Deoxyribonuclease I enzyme No known significant effects or critical hazards. Reconstitution Buffer H320 - Causes eye irritation. Digestion Buffer H226 - Flammable liquid and vapor. H319 - Causes serious eye irritation. H335 - May cause respiratory irritation. H336 - May cause drowsiness and dizziness. H373 - May cause damage to organs through prolonged or repeated exposure. Proteinase K H320 - Causes eye irritation. Proteinase K Digestion Buffer No known significant effects or critical hazards. Stratagene QPCR Human No known significant effects or critical hazards. Reference Total RNA De-paraffinization Reagent (d- H226 - Flammable liquid and vapor. limonene) H315 + H320 - Causes skin and eye irritation. H317 - May cause an allergic skin reaction.

Prevention

RNA Binding Buffer P271 - Use only outdoors or in a well-ventilated area. P261 - Avoid breathing vapor. P270 - Do not eat, drink or smoke when using this product. P264 - Wash hands thoroughly after handling. 1.67x High-Salt Wash Buffer P271 - Use only outdoors or in a well-ventilated area. P261 - Avoid breathing vapor. P270 - Do not eat, drink or smoke when using this product. P264 - Wash hands thoroughly after handling. 5x Low-Salt Wash Buffer Not applicable. Elution Buffer Not applicable. Beta-mercaptoethanol P280 - Wear protective gloves. Wear eye or face protection. P284 - Wear respiratory protection. P210 - Keep away from flames and hot surfaces. - No smoking. P271 - Use only outdoors or in a well-ventilated area. P262 - Do not get in eyes, on skin, or on clothing. P260 - Do not breathe vapor. P270 - Do not eat, drink or smoke when using this product. P264 - Wash hands thoroughly after handling. P272 - Contaminated work clothing should not be allowed out of the workplace. Deoxyribonuclease I enzyme Not applicable. Reconstitution Buffer P280 - Wear eye or face protection. P264 - Wash hands thoroughly after handling. Digestion Buffer P280 - Wear protective gloves. Wear eye or face protection. P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P241 - Use explosion-proof electrical, ventilating, lighting and all material-handling equipment. P242 - Use only non-sparking tools. P243 - Take precautionary measures against static discharge. P233 - Keep container tightly closed. P271 - Use only outdoors or in a well-ventilated area. P260 - Do not breathe vapor. P264 - Wash hands thoroughly after handling. Proteinase K P280 - Wear eye or face protection. P264 - Wash hands thoroughly after handling. Proteinase K Digestion Buffer Not applicable. Stratagene QPCR Human Not applicable. Reference Total RNA De-paraffinization Reagent (d- P280 - Wear protective gloves. Wear eye or face limonene) protection. P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P241 - Use explosion-proof electrical, ventilating, lighting and all material-handling equipment. P242 - Use only non-sparking tools. P243 - Take precautionary measures against static discharge. P233 - Keep container tightly closed. P261 - Avoid breathing vapor. P264 - Wash hands thoroughly after handling. P272 - Contaminated work clothing should not be allowed out of the workplace.

Response

RNA Binding Buffer P304 + P340 + P312 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or physician if you feel unwell. P301 + P312 + P330 - IF SWALLOWED: Call a POISON CENTER or physician if you feel unwell. Rinse mouth. 1.67x High-Salt Wash Buffer P304 + P340 + P312 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or physician if you feel unwell. P301 + P312 + P330 - IF SWALLOWED: Call a POISON CENTER or physician if you feel unwell. Rinse mouth. 5x Low-Salt Wash Buffer Not applicable. Elution Buffer Not applicable. Beta-mercaptoethanol P304 + P340 + P310 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or physician. P301 + P310 + P330 - IF SWALLOWED: Immediately call a POISON CENTER or physician. Rinse mouth. P302 + P361 + P350 + P310 + P362-2 + P363 - IF ON SKIN: Take off immediately all contaminated clothing. Gently wash with plenty of soap and water. Immediately call a POISON CENTER or physician. Take off contaminated clothing. Wash contaminated clothing before reuse. P333 + P313 - If skin irritation or rash occurs: Get medical attention. P305 + P351 + P338 + P310 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or physician. Deoxyribonuclease I enzyme Not applicable. Reconstitution Buffer P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. Digestion Buffer P314 - Get medical attention if you feel unwell. P304 + P340 + P312 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or physician if you feel unwell. P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. Proteinase K P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. Proteinase K Digestion Buffer Not applicable. Stratagene QPCR Human Not applicable. Reference Total RNA De-paraffinization Reagent (d- P303 + P361 + P353 - IF ON SKIN (or hair): Take limonene) off immediately all contaminated clothing. Rinse skin with water or shower. P302 + P352 + P362-2 - IF ON SKIN: Wash with plenty of soap and water. Take off contaminated clothing. P333 + P313 - If skin irritation or rash occurs: Get medical attention. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention.

Storage

RNA Binding Buffer Not applicable. 1.67x High-Salt Wash Buffer Not applicable. 5x Low-Salt Wash Buffer Not applicable. Elution Buffer Not applicable. Beta-mercaptoethanol P405 - Store locked up. P403 - Store in a well-ventilated place. P235 - Keep cool. Deoxyribonuclease I enzyme Not applicable. Reconstitution Buffer Not applicable. Digestion Buffer P405 - Store locked up. P403 - Store in a well-ventilated place. P235 - Keep cool. Proteinase K Not applicable. Proteinase K Digestion Buffer Not applicable. Stratagene QPCR Human Not applicable. Reference Total RNA De-paraffinization Reagent (d- P403 - Store in a well-ventilated place. limonene) P235 - Keep cool.

Disposal

RNA Binding Buffer P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. 1.67x High-Salt Wash Buffer P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. 5x Low-Salt Wash Buffer Not applicable. Elution Buffer Not applicable. Beta-mercaptoethanol P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. Deoxyribonuclease I enzyme Not applicable. Reconstitution Buffer Not applicable. Digestion Buffer P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. Proteinase K Not applicable. Proteinase K Digestion Buffer Not applicable. Stratagene QPCR Human Not applicable. Reference Total RNA De-paraffinization Reagent (d- P501 - Dispose of contents and container in limonene) accordance with all local, regional, national and international regulations.

2.3 Other hazards

Hazards not otherwise : RNA Binding Buffer None known. classified 1.67x High-Salt Wash Buffer None known. 5x Low-Salt Wash Buffer None known. Elution Buffer None known. Beta-mercaptoethanol None known. Deoxyribonuclease I enzyme None known. Reconstitution Buffer None known. Digestion Buffer Defatting to the skin. Proteinase K None known. Proteinase K Digestion Buffer Prolonged or repeated contact may dry skin and cause irritation. Stratagene QPCR Human None known. Reference Total RNA De-paraffinization Reagent (d- None known. limonene)