Absolutely miRNA Total Isolation Kit, Part Number 400814

Hazard statements (CLP)

H226, H227, H301, H302, H310, H315, H317, H318, H319, H320, H335, H336, H373

Code

Statements

H226

Flammable liquid and vapour

2.1 Classification of the substance or mixture

OSHA/HCS status : Lysis Buffer This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). 1.67x High-Salt Wash Buffer This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). 5x Low-Salt Wash Buffer While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product. Elution Buffer While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product. Reconstitution Buffer This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). Digestion Buffer This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). 14.2 M Beta-mercaptoethanol This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). Deoxyribonuclease I enzyme While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product. Lysis Buffer H302 ACUTE TOXICITY (oral) - Category 4 1.67x High-Salt Wash Buffer H302 ACUTE TOXICITY (oral) - Category 4 Reconstitution Buffer H320 SERIOUS EYE DAMAGE/ EYE IRRITATION - Category 2B H373 SPECIFIC TARGET ORGAN TOXICITY (REPEATED EXPOSURE) - Category 2 Digestion Buffer H226 FLAMMABLE LIQUIDS - Category 3 H319 SERIOUS EYE DAMAGE/ EYE IRRITATION - Category 2A H335 and H336 SPECIFIC TARGET ORGAN TOXICITY (SINGLE EXPOSURE) (Respiratory tract irritation and Narcotic effects) - Category 3 H373 SPECIFIC TARGET ORGAN TOXICITY (REPEATED EXPOSURE) - Category 2 14.2 M Beta-mercaptoethanol H227 FLAMMABLE LIQUIDS - Category 4 H301 ACUTE TOXICITY (oral) - Category 3 H310 ACUTE TOXICITY (dermal) - Category 2 H315 SKIN CORROSION/IRRITATION - Category 2 H318 SERIOUS EYE DAMAGE/ EYE IRRITATION - Category 1 H317 SKIN SENSITIZATION - Category 1 H335 SPECIFIC TARGET ORGAN TOXICITY (SINGLE EXPOSURE) (Respiratory tract irritation) - Category 3 Lysis Buffer Not applicable. 1.67x High-Salt Wash Buffer Percentage of the mixture consisting of ingredient (s) of unknown toxicity: 1.2% 5x Low-Salt Wash Buffer Not applicable. Elution Buffer Not applicable. Reconstitution Buffer Not applicable. Digestion Buffer Not applicable. Ingredients of unknown 14.2 M Beta-mercaptoethanol Not applicable. toxicity Deoxyribonuclease I enzyme Not applicable.

Signal word

Lysis Buffer Warning 1.67x High-Salt Wash Buffer Warning 5x Low-Salt Wash Buffer No signal word. Elution Buffer No signal word. Reconstitution Buffer Warning Digestion Buffer Warning 14.2 M Beta-mercaptoethanol Danger Deoxyribonuclease I enzyme No signal word.

Hazard statements

Lysis Buffer H302 - Harmful if swallowed. 1.67x High-Salt Wash Buffer H302 - Harmful if swallowed. 5x Low-Salt Wash Buffer No known significant effects or critical hazards. Elution Buffer No known significant effects or critical hazards. Reconstitution Buffer H320 - Causes eye irritation. H373 - May cause damage to organs through prolonged or repeated exposure. Digestion Buffer H226 - Flammable liquid and vapor. H319 - Causes serious eye irritation. H335 - May cause respiratory irritation. H336 - May cause drowsiness and dizziness. H373 - May cause damage to organs through prolonged or repeated exposure. 14.2 M Beta-mercaptoethanol H227 - Combustible liquid. H310 - Fatal in contact with skin. H301 - Toxic if swallowed. H318 - Causes serious eye damage. H315 - Causes skin irritation. H317 - May cause an allergic skin reaction. H335 - May cause respiratory irritation. Deoxyribonuclease I enzyme No known significant effects or critical hazards.

Prevention

Lysis Buffer P270 - Do not eat, drink or smoke when using this product. P264 - Wash hands thoroughly after handling. 1.67x High-Salt Wash Buffer P270 - Do not eat, drink or smoke when using this product. P264 - Wash hands thoroughly after handling. 5x Low-Salt Wash Buffer Not applicable. Elution Buffer Not applicable. Reconstitution Buffer P280 - Wear eye or face protection. P260 - Do not breathe vapor. P264 - Wash hands thoroughly after handling. Digestion Buffer P280 - Wear protective gloves. Wear eye or face protection. P210 - Keep away from heat, sparks, open flames and hot surfaces. - No smoking. P241 - Use explosion-proof electrical, ventilating, lighting and all material-handling equipment. P242 - Use only non-sparking tools. P243 - Take precautionary measures against static discharge. P233 - Keep container tightly closed. P271 - Use only outdoors or in a well-ventilated area. P260 - Do not breathe vapor. P264 - Wash hands thoroughly after handling. 14.2 M Beta-mercaptoethanol P280 - Wear protective gloves. Wear eye or face protection. Wear protective clothing. P210 - Keep away from flames and hot surfaces. - No smoking. P271 - Use only outdoors or in a well-ventilated area. P262 - Do not get in eyes, on skin, or on clothing. P261 - Avoid breathing vapor. P270 - Do not eat, drink or smoke when using this product. P264 - Wash hands thoroughly after handling. P272 - Contaminated work clothing should not be allowed out of the workplace. Deoxyribonuclease I enzyme Not applicable.

Response

Lysis Buffer P301 + P312 + P330 - IF SWALLOWED: Call a POISON CENTER or physician if you feel unwell. Rinse mouth. 1.67x High-Salt Wash Buffer P301 + P312 + P330 - IF SWALLOWED: Call a POISON CENTER or physician if you feel unwell. Rinse mouth. 5x Low-Salt Wash Buffer Not applicable. Elution Buffer Not applicable. Reconstitution Buffer P314 - Get medical attention if you feel unwell. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. Digestion Buffer P314 - Get medical attention if you feel unwell. P304 + P340 + P312 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or physician if you feel unwell. P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. 14.2 M Beta-mercaptoethanol P304 + P340 + P312 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or physician if you feel unwell. P301 + P310 + P330 - IF SWALLOWED: Immediately call a POISON CENTER or physician. Rinse mouth. P302 + P361 + P350 + P310 + P362-2 + P363 - IF ON SKIN: Take off immediately all contaminated clothing. Gently wash with plenty of soap and water. Immediately call a POISON CENTER or physician. Take off contaminated clothing. Wash contaminated clothing before reuse. P333 + P313 - If skin irritation or rash occurs: Get medical attention. P305 + P351 + P338 + P310 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or physician. Deoxyribonuclease I enzyme Not applicable.

Storage

Lysis Buffer Not applicable. 1.67x High-Salt Wash Buffer Not applicable. 5x Low-Salt Wash Buffer Not applicable. Elution Buffer Not applicable. Reconstitution Buffer Not applicable. Digestion Buffer P405 - Store locked up. P403 - Store in a well-ventilated place. P235 - Keep cool. 14.2 M Beta-mercaptoethanol P405 - Store locked up. P403 - Store in a well-ventilated place. P235 - Keep cool. Deoxyribonuclease I enzyme Not applicable.

Disposal

Lysis Buffer P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. 1.67x High-Salt Wash Buffer P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. 5x Low-Salt Wash Buffer Not applicable. Elution Buffer Not applicable. Reconstitution Buffer P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. Digestion Buffer P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. 14.2 M Beta-mercaptoethanol P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. Deoxyribonuclease I enzyme Not applicable.

Supplemental label elements

Lysis Buffer None known. elements 1.67x High-Salt Wash Buffer None known. 5x Low-Salt Wash Buffer None known. Elution Buffer None known. Reconstitution Buffer None known. Digestion Buffer None known. 14.2 M Beta-mercaptoethanol None known. Deoxyribonuclease I enzyme None known.

2.3 Other hazards

Hazards not otherwise : Lysis Buffer None known. classified 1.67x High-Salt Wash Buffer None known. 5x Low-Salt Wash Buffer None known. Elution Buffer None known. Reconstitution Buffer None known. Digestion Buffer None known. 14.2 M Beta-mercaptoethanol None known. Deoxyribonuclease I enzyme None known.