SureSelect XT Low Input Reagent Kit, index 97-192 + Human All Exon V7 Target

2.1 Classification of the substance or mixture

Not classified. End Repair-A Tailing Percentage of the mixture consisting of ingredient(s) Enzyme Mix of unknown acute inhalation toxicity: 30 - 60% End Repair-A Tailing Buffer Percentage of the mixture consisting of ingredient(s) of unknown acute dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient(s) of unknown acute inhalation toxicity: 1 - 10% Percentage of the mixture consisting of ingredient(s) of unknown acute oral toxicity: 1 - 10% T4 DNA Ligase Percentage of the mixture consisting of ingredient(s) of unknown acute inhalation toxicity: 30 - 60% Ligation Buffer Percentage of the mixture consisting of ingredient(s) of unknown acute inhalation toxicity: 30 - 60% 100 mM dNTP Mix (25 mM Percentage of the mixture consisting of ingredient(s) each dNTP) of unknown acute dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient(s) of unknown acute inhalation toxicity: 1 - 10% Percentage of the mixture consisting of ingredient(s) of unknown acute oral toxicity: 1 - 10% Herculase II Fusion DNA Percentage of the mixture consisting of ingredient(s) Polymerase of unknown acute inhalation toxicity: 30 - 60% 5X Herculase II Reaction Percentage of the mixture consisting of ingredient(s) Buffer of unknown acute dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient(s) of unknown acute inhalation toxicity: 1 - 10% SureSelect Binding Buffer Percentage of the mixture consisting of ingredient(s) of unknown acute inhalation toxicity: 1 - 10% SureSelect Fast Percentage of the mixture consisting of ingredient(s) Hybridization Buffer of unknown acute dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient(s) of unknown acute inhalation toxicity: 30 - 60% Percentage of the mixture consisting of ingredient(s) of unknown acute oral toxicity: 1 - 10% SureSelect RNase Block Percentage of the mixture consisting of ingredient(s) of unknown acute inhalation toxicity: 30 - 60% SSEL XT HS and XT Low Percentage of the mixture consisting of ingredient(s) Input Custom Capture Library of unknown acute inhalation toxicity: 1 - 10% End Repair-A Tailing Buffer Percentage of the mixture consisting of ingredient(s) of unknown hazards to the aquatic environment: 1.7% 100 mM dNTP Mix (25 mM Percentage of the mixture consisting of ingredient(s) each dNTP) of unknown hazards to the aquatic environment: 5.4% SureSelect Fast Percentage of the mixture consisting of ingredient(s) Hybridization Buffer of unknown hazards to the aquatic environment: 1.6%

Signal word

End Repair-A Tailing No signal word. Enzyme Mix End Repair-A Tailing Buffer No signal word. T4 DNA Ligase No signal word. Ligation Buffer No signal word. Adaptor Oligo Mix No signal word. Forward Primer No signal word. 100 mM dNTP Mix (25 mM No signal word. each dNTP) Herculase II Fusion DNA No signal word. Polymerase 5X Herculase II Reaction No signal word. Buffer SureSelect Binding Buffer No signal word. SureSelect Wash Buffer 1 No signal word. SureSelect Wash Buffer 2 No signal word. SureSelect XT HS and XT No signal word. Low Input Blocker Mix SureSelect Fast No signal word. Hybridization Buffer SureSelect RNase Block No signal word. SureSelect Post-Capture No signal word. Primer Mix SureSelect XT Low Input No signal word. Index Bulk Set 2 A01-H12 SSEL XT HS and XT Low No signal word. Input Custom Capture Library SSel XT Low Input Human No signal word. All Exon V7, 96 Reactions Automation

Hazard statements

End Repair-A Tailing No known significant effects or critical hazards. Enzyme Mix End Repair-A Tailing Buffer No known significant effects or critical hazards. T4 DNA Ligase No known significant effects or critical hazards. Ligation Buffer No known significant effects or critical hazards. Adaptor Oligo Mix No known significant effects or critical hazards. Forward Primer No known significant effects or critical hazards. 100 mM dNTP Mix (25 mM No known significant effects or critical hazards. each dNTP) Herculase II Fusion DNA No known significant effects or critical hazards. Polymerase 5X Herculase II Reaction No known significant effects or critical hazards. Buffer SureSelect Binding Buffer No known significant effects or critical hazards. SureSelect Wash Buffer 1 No known significant effects or critical hazards. SureSelect Wash Buffer 2 No known significant effects or critical hazards. SureSelect XT HS and XT No known significant effects or critical hazards. Low Input Blocker Mix SureSelect Fast No known significant effects or critical hazards. Hybridization Buffer SureSelect RNase Block No known significant effects or critical hazards. SureSelect Post-Capture No known significant effects or critical hazards. Primer Mix SureSelect XT Low Input No known significant effects or critical hazards. Index Bulk Set 2 A01-H12 SSEL XT HS and XT Low No known significant effects or critical hazards. Input Custom Capture Library SSel XT Low Input Human No known significant effects or critical hazards. All Exon V7, 96 Reactions Automation

Prevention

End Repair-A Tailing Not applicable. Enzyme Mix End Repair-A Tailing Buffer Not applicable. T4 DNA Ligase Not applicable. Ligation Buffer Not applicable. Adaptor Oligo Mix Not applicable. Forward Primer Not applicable. 100 mM dNTP Mix (25 mM Not applicable. each dNTP) Herculase II Fusion DNA Not applicable. Polymerase 5X Herculase II Reaction Not applicable. Buffer SureSelect Binding Buffer Not applicable. SureSelect Wash Buffer 1 Not applicable. SureSelect Wash Buffer 2 Not applicable. SureSelect XT HS and XT Not applicable. Low Input Blocker Mix SureSelect Fast Not applicable. Hybridization Buffer SureSelect RNase Block Not applicable. SureSelect Post-Capture Not applicable. Primer Mix SureSelect XT Low Input Not applicable. Index Bulk Set 2 A01-H12 SSEL XT HS and XT Low Not applicable. Input Custom Capture Library SSel XT Low Input Human Not applicable. All Exon V7, 96 Reactions Automation

Response

End Repair-A Tailing Not applicable. Enzyme Mix End Repair-A Tailing Buffer Not applicable. T4 DNA Ligase Not applicable. Ligation Buffer Not applicable. Adaptor Oligo Mix Not applicable. Forward Primer Not applicable. 100 mM dNTP Mix (25 mM Not applicable. each dNTP) Herculase II Fusion DNA Not applicable. Polymerase 5X Herculase II Reaction Not applicable. Buffer SureSelect Binding Buffer Not applicable. SureSelect Wash Buffer 1 Not applicable. SureSelect Wash Buffer 2 Not applicable. SureSelect XT HS and XT Not applicable. Low Input Blocker Mix SureSelect Fast Not applicable. Hybridization Buffer SureSelect RNase Block Not applicable. SureSelect Post-Capture Not applicable. Primer Mix SureSelect XT Low Input Not applicable. Index Bulk Set 2 A01-H12 SSEL XT HS and XT Low Not applicable. Input Custom Capture Library SSel XT Low Input Human Not applicable. All Exon V7, 96 Reactions Automation

Storage

End Repair-A Tailing Not applicable. Enzyme Mix End Repair-A Tailing Buffer Not applicable. T4 DNA Ligase Not applicable. Ligation Buffer Not applicable. Adaptor Oligo Mix Not applicable. Forward Primer Not applicable. 100 mM dNTP Mix (25 mM Not applicable. each dNTP) Herculase II Fusion DNA Not applicable. Polymerase 5X Herculase II Reaction Not applicable. Buffer SureSelect Binding Buffer Not applicable. SureSelect Wash Buffer 1 Not applicable. SureSelect Wash Buffer 2 Not applicable. SureSelect XT HS and XT Not applicable. Low Input Blocker Mix SureSelect Fast Not applicable. Hybridization Buffer SureSelect RNase Block Not applicable. SureSelect Post-Capture Not applicable. Primer Mix SureSelect XT Low Input Not applicable. Index Bulk Set 2 A01-H12 SSEL XT HS and XT Low Not applicable. Input Custom Capture Library SSel XT Low Input Human Not applicable. All Exon V7, 96 Reactions Automation

Disposal

End Repair-A Tailing Not applicable. Enzyme Mix End Repair-A Tailing Buffer Not applicable. T4 DNA Ligase Not applicable. Ligation Buffer Not applicable. Adaptor Oligo Mix Not applicable. Forward Primer Not applicable. 100 mM dNTP Mix (25 mM Not applicable. each dNTP) Herculase II Fusion DNA Not applicable. Polymerase 5X Herculase II Reaction Not applicable. Buffer SureSelect Binding Buffer Not applicable. SureSelect Wash Buffer 1 Not applicable. SureSelect Wash Buffer 2 Not applicable. SureSelect XT HS and XT Not applicable. Low Input Blocker Mix SureSelect Fast Not applicable. Hybridization Buffer SureSelect RNase Block Not applicable. SureSelect Post-Capture Not applicable. Primer Mix SureSelect XT Low Input Not applicable. Index Bulk Set 2 A01-H12 SSEL XT HS and XT Low Not applicable. Input Custom Capture Library SSel XT Low Input Human Not applicable. All Exon V7, 96 Reactions Automation

Supplemental label elements

elements Additional warning : End Repair-A Tailing Not applicable. phrases Enzyme Mix End Repair-A Tailing Buffer Not applicable. T4 DNA Ligase Not applicable. Ligation Buffer Not applicable. Adaptor Oligo Mix Not applicable. Forward Primer Not applicable. 100 mM dNTP Mix (25 mM Not applicable. each dNTP) Herculase II Fusion DNA Not applicable. Polymerase 5X Herculase II Reaction Not applicable. Buffer SureSelect Binding Buffer Not applicable. SureSelect Wash Buffer 1 Not applicable. SureSelect Wash Buffer 2 Not applicable. SureSelect XT HS and XT Not applicable. Low Input Blocker Mix SureSelect Fast Not applicable. Hybridization Buffer SureSelect RNase Block Not applicable. SureSelect Post-Capture Not applicable. Primer Mix SureSelect XT Low Input Not applicable. Index Bulk Set 2 A01-H12 SSEL XT HS and XT Low Not applicable. Input Custom Capture Library SSel XT Low Input Human Not applicable. All Exon V7, 96 Reactions Automation Other hazards which do not : End Repair-A Tailing None known. result in classification Enzyme Mix End Repair-A Tailing Buffer None known. T4 DNA Ligase None known. Ligation Buffer None known. Adaptor Oligo Mix None known. Forward Primer None known. 100 mM dNTP Mix (25 mM None known. each dNTP) Herculase II Fusion DNA None known. Polymerase 5X Herculase II Reaction None known. Buffer SureSelect Binding Buffer None known. SureSelect Wash Buffer 1 None known. SureSelect Wash Buffer 2 None known. SureSelect XT HS and XT None known. Low Input Blocker Mix SureSelect Fast None known. Hybridization Buffer SureSelect RNase Block None known. SureSelect Post-Capture None known. Primer Mix SureSelect XT Low Input None known. Index Bulk Set 2 A01-H12 SSEL XT HS and XT Low None known. Input Custom Capture Library SSel XT Low Input Human None known. All Exon V7, 96 Reactions Automation